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William M. Brooks, PhD

William Brooks portrait
Professor, Neurology

Professor, Molecular and Integrative Physiology

Professor, Neurology

Professor, Neurology

wbrooks@kumc.edu

Professional Background

William Brooks, Ph.D., is the director of the Hoglund Biomedical Imaging Center at the University of Kansas Medical Center. He received a bachelor of science with honors from Griffith University in 1979 and a Ph.D. from Griffith University in 1984. After initial work as a research officer in Brisbane, Australia, he became the scientific director at the Center for Non-Invasive Diagnosis (re-named the Clinical and Magnetic Resonance Research Center in 1997) at the University of New Mexico in Albuquerque. He had joint appointments in the departments of Neurosciences, Cell Biology and Psychology.

Dr. Brooks joined the faculty at the University of Kansas Medical Center in 2002, where he is a professor in the Department of Neurology. He has been a leader in the field of magnetic resonance imaging and magnetic resonance spectroscopy in a wide range of neurological and psychiatric disorders with focus on traumatic brain injury, neuropsychiatric syndromes associated with systemic lupus erythematosus, post-traumatic stress disorder and stroke.

Education and Training
  • BSc, Chemistry, Griffith University, Brisbane, Queensland
  • PhD, Chemistry, Griffith University, Brisbane, Queensland
  • Post Doctoral Fellowship, Chemistry, Griffith University, Brisbane, Qld
  • Post Doctoral Fellowship, University of Queensland, Brisbane, Qld
Professional Affiliations
  • KUMC, University of Kansas Cancer Center Investigator Initiated Trial Steering Committee, Member, 2019 - Present
  • KUMC, Kansas Intellectual & Developmental Disabilities Research Center - Clinical Outcomes/Biobehavioral Technology Core, Director, 2016 - Present
  • KUMC, Department of Neurology Executive Committee, Ex-Officio, 2016 - Present
  • KUMC, Kansas PKD Research and Translational Core Center Biomarkers Core, Co-Investigator - KU PKD Center Biomarkers Core, 2015 - 2020
  • KUMC, Department of Neurology Executive Committee, Member, 2014 - 2016
  • KUMC, KU Alzheimer's Disease Center Neuroimaging Core, Director, 2011 - Present
  • International Neurotrauma Society, Member, 2001 - Present

Research

Overview

Dr. Brooks’ specific research interests include normal function and recovery from traumatic brain injury. He has published more than 100 peer-reviewed journal articles, three patents, and is funded to study traumatic brain injury.

Publications
  • Mansour, Zaid, Martin, Laura, Lepping, Rebecca, Kanaan, Saddam, Brooks, William, Yeh, Hung-Wen, Sharma, Neena. 2018. Brain Response to Non-Painful Mechanical Stimulus to Lumbar Spine. Brain sciences, 8 (3), 41
  • Pierce, J., D, Gupte, R, Thimmesch, A, Shen, Q, Hiebert, J., B, Brooks, W., M, Clancy, R., L, Diaz, F., J, Harris, J., L. 2018. Ubiquinol treatment for TBI in male rats: Effects on mitochondrial integrity, injury severity, and neurometabolism.. Journal of Neuroscience Research, 96 (6), 1080-1092
  • Vogel, Jacob., W, Vachon-Presseau, Etienne, Pichet Binette, Alexa, Tam, Angela, Orban, Pierre, La Joie, Renaud, Savard, M\'elissa, Picard, Cynthia, Poirier, Judes, Bellec, Pierre, others. 2018. Brain properties predict proximity to symptom onset in sporadic Alzheimer’s disease. Brain, 141 (6), 1871--1883
  • Gupta, Aditi, Montgomery, Robert., N, Bedros, Victor, Lesko, John, Mahnken, Jonathan., D, Chakraborty, Shweta, Drew, David, Klein, Jeffrey., A, Thomas, Tashra., S, Ilahe, Amna, others. 2019. Subclinical Cognitive Impairment and Listing for Kidney Transplantation. Clinical Journal of the American Society of Nephrology, CJN--11010918
  • Gupte, Raeesa, Brooks, William., M, Vukas, Rachel., R, Pierce, Janet., D, Harris, Janna., L. 2019. Sex differences in traumatic brain injury: What we know and what we should know. Journal of neurotrauma, 36 (22), 3063-3091
  • Lepping, Rebecca., J, Honea, Robyn., A, Martin, Laura., E, Liao, Ke, Choi, In-Young, Lee, Phil, Papa, Vlad., B, Brooks, William., M, Shaddy, D., Jill, Carlson, Susan., E, others. 2019. Long-chain polyunsaturated fatty acid supplementation in the first year of life affects brain function, structure, and metabolism at age nine years. Developmental psychobiology, 61 (1), 5--16
  • Devos, H, Burns, J., M, Liao, K, Ahmadnezhad, P, Mahnken, J., D, Brooks, W., M, Gustafson, K. 2020. Reliability of P3 Event-Related Potential During Working Memory Across the Spectrum of Cognitive Aging.. Frontiers in aging neuroscience, 12, 566391
  • Devos, H, Gustafson, K, Ahmadnezhad, P, Liao, K, Mahnken, J., D, Brooks, W., M, Burns, J., M. 2020. Psychometric Properties of NASA-TLX and Index of Cognitive Activity as Measures of Cognitive Workload in Older Adults.. Brain sciences, 10 (12)
  • El Ters, M, Zhou, X, Lepping, R., J, Lu, P, Karcher, R., T, Mahnken, J., D, Brooks, W., M, Winklhofer, F., T, Li , X, Yu ASL. 2020. Biological Efficacy and Safety of Niacinamide in Patients With ADPKD.. Kidney international reports, 5 (8), 1271-1279
  • Lepping, R., J, Montgomery, R., N, Sharma, P, Mahnken, J., D, Vidoni, E., D, Choi, I., Y, Sarnak, M., J, Brooks, W., M, Burns, J., M, Gupta, A. 2021. Normalization of Cerebral Blood Flow, Neurochemicals, and White Matter Integrity after Kidney Transplantation.. Journal of the American Society of Nephrology : JASN, 32 (1), 177-187