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Steven A. Weinman, M.D., PhD

Steven Weinman portrait
Professor, Gastroenterology, Hepatology & Motility

Director, Liver Center

Vice Chair for Research, Department of Internal Medicine

Professor, Microbiology, Molecular Genetics and Immunology

Research Professor, Kansas City Veterans Administration Medical Center

Professional Background

Dr. Weinman received his bachelor’s degree from Harvard College and completed a combined MD-PhD degree at Washington University in St. Louis. He subsequently did Internal Medicine Residency and Gastroenterology Fellowship at Yale University and has been on the faculty at KUMC since 2009.

He has an active clinical practice and research program in Liver Disease. He is best known for his work on pathogenic mechanisms in Hepatitis C where his lab was the first to demonstrate the interactions of HCV viral proteins with mitochondria and the impact of these interactions on liver oxidative stress pathways. In recent years his work has focused on the cellular mechanisms of steatohepatitis, particularly in alcohol-associated liver disease, and the role of macrophages in liver disease.
His research accomplishments have been recognized with the KU Research Investigator Award, membership on multiple NIH study sections serving as Chairman for 6 of these panels. He is a past editorial board member for Hepatology, Hepatology Communications (Associate Editor), American Journal of Physiology and is currently Field Editor for Alcohol: Clinical and Experimental Research. He is Fellow of the American Gastroenterological Association and the American Association for the Study of Liver Diseases where he serves on multiple committees. As Director of the Liver Center at KUMC Dr. Weinman oversees the Hepatology Clinical Studies Unit and the Liver Tissue Bank which collects and distributes liver tissue and blood samples. These facilities directly support clinical and translational research by providing resources and skilled clinical research coordinator expertise to individuals engaged in investigator-initiated clinical research in Liver Disease. Dr. Weinman has been active in mentoring and development of junior colleagues for many years and is the recipient of the University of Kansas Excellence in Mentoring Award in 2019.

Education and Training
  • BA, Biochemistry, Harvard University, Cambridge, MA
  • PhD, Cell Biology, Washington University, St. Louis, MO
  • MD, Medicine, Washington University, St. Louis, MO
  • Internship, Internal Medicine, Yale-New Haven Hospital, New Haven, CT
  • Residency, Internal Medicine, Yale - New Haven Hospital, New Haven, CT
  • Clinical Fellowship, Digestive Diseases, Yale University School of Medicine, New Haven, Connecticut
Licensure, Accreditations & Certifications
  • Gastroenterology, American Board of Internal Medicine
  • Internal Medicine, American Board of Internal Medicine
  • Kansas Medical License, Kansas State Board of Medical Healing Arts
  • Missouri Medical License, Missouri Board of Healing Arts
Professional Affiliations
  • American Association for the Study of Liver Diseases, Fellow, 2014 - Present
  • American Gastroenterological Association, Fellow, 2005 - Present
  • Research Society on Alcohol, Member, 2005 - Present
  • American Association for the Study of Liver Diseases, Member, 1989 - Present



Our research is focused on understanding the role of macrophages in alcohol-induced liver injury. The ultimate goal of these studies is to develop therapies that can prevent liver failure and improve the outcomes of patients with alcohol-associated liver disease.

Current Research and Grants
  • Role of alcohol adapted Kupffer cells in the progression and resolution of ALD, NIH NIAAA, PI
  • Kansas Center for Metabolism and Obesity Research (KC-MORE), NIH, Co-PI