Patrick R Gonzales, PhD
Clinical Assistant Professor
Co-Director, Cytogenetics Laboratory
Consultant, Clinical Molecular Oncology Laboratory
BS, Biology, University of California - Los Angeles
MS, Cellular and Molecular Biology, University of Wisconsin - LaCrosse
PhD, Molecular Genetics and Genomics, Washington University, St. Louis, Missouri
Publications: Click here
ABMGG Fellowship, Clinical Cytogenetics and Genomics, University of Alabama at Birmingham, 2017
ABMGG Fellowship, Clinical Molecular Genetics and Genomics, University of Alabama at Birmingham, 2018
Clinical Cytogenetics and Genomics, American Board of Medical Genetics and Genomics, 2017
Clinical Molecular Genetics and Genomics, American Board of Medical Genetics and Genomics, 2019
My daily work involves the review and interpretation of clinical results from cytogenetic and molecular genetic testing. The samples we receive include hematological specimens such as bone marrow and whole blood, along with solid tumors. The techniques we use include: Conventional G-banded chromosome analysis, Fluorescence In Situ Hybridization (FISH), PCR and Next-Generation Sequencing (NGS).
The Cytogenetics and Clinical Molecular Oncology Labs provide quality and timely testing of neoplastic specimens for structural and sequence variants that may play a crucial role in diagnosis and prognosis of cancer. These results aid our physicians to properly diagnose and treat our patients at KUMC.
Educational Responsibilities: My educational responsibilities include teaching clinical cytogenetics to KUMC medical students, residents and fellows, through didactic lectures and workshops.
|Fig. 1: FISH probe strategies for analysis of recurrent chromosomal abnormalities in AML, including the use of deletion/duplication (Del/Dup) probes, b break-apart probes (BAP), c and d dual-color/dual-fusion (DC/DF) probes. From Curr Hematol Malig Rep (2017) 12: 568-573.|