Skip to main content

Clinical Trials

Clinical Research Team

We give patients access to the most advanced therapies and techniques through clinical research in otolaryngology, otology, oncology, and rhinology. The Department conducts ongoing, critical review of the care we provide to our patients. Retrospective studies, including multicenter projects, serve to analyze the patterns and outcomes for patients with the aim of improving the evidence base for our treatment options and generating hypotheses for future research. Utilizing large national administrative datasets allows for health services research that examines similar questions on a national scale looking for trends and opportunities for improvements in care related to otolaryngology as it is performed in the United States.

Kevin Sykes, PhD, MPH leads this division of the department as the Director of Clinical Research and has been in this role since 2005. This is a team effort and critical to our success is the experience and effort of our Clinical Research Coordinator, Bryan Humphrey, RRT-NPS. Since 2010, we have offered full-time or part-time research assistant positions for students interested in medical school. In 2016, we began a Research Fellowship that provides a year of research experience.  The clinical research team currently includes Research Assistant Joseph Penn, BS; Research Fellow Rohit Nallani, MD; Research Fellow Josh Smith, MD; and Administrative Assistant Jaci Blancarte. 

As one of the leading neurotology sites in the United States for hearing and balance related research and clinical trials, we attract patients from across the country interested in advancing science and receiving care that is only offered at select institutions. This research includes a first of its kind Phase I clinical trial testing the safety and tolerability of an inner ear infusion of CGF166, a gene therapy aiming to treat severe to profound hearing loss. We also routinely offer clinical trials in head and neck oncology, pediatric otolaryngology, and rhinology. We are currently enrolling in the clinical trials listed below, and one of our clinical research team members would be happy to help you learn more about these trials.

To register as a clinical trial volunteer, go to the KUMC website for volunteers.

To confirm your eligibility to participate in a clinical trial, contact our clinical research office by emailing or by dialing (913) 588-6701. 

1st Clinical Trial to Restore Hearing

Fifteen years of research by Dr. Hinrich Staecker are behind a clinical study to implant a remarkable virus to restore hearing in patients with severe hearing loss. 

Active Clinical Research Trials in the Department of Otolaryngology-Head and Neck Surgery


Long-term Safety and Efficacy Follow-up Study of CGF166-Treated Patients                
Principal Investigator: Hinrich Staecker, MD, PhD 

The HEARRING Registry, Quality of Life Assessment, and Genetic Sub-Studies - A Collaborative Effort for Global Outcomes with MED-EL Hearing Implants
Principal Investigator: Hinrich Staecker, MD, PhD   

Electric-Acoustic Stimulation Extended Follow-up Post-Approval Study
Principal Investigator: Hinrich Staecker, MD, PhD

General Otolaryngology

Adherence and Outcome of Upper Airway Stimulation (UAS) for OSA International Registry (ADHERE)
Principal Investigator: Christopher Larsen, MD  

Drug Induced Sleep Endoscopy Evaluation of Airway Changes with Hyo-Mandibular Suspension
Principal Investigator: Christopher Larsen, MD  

Prospective, Non-Randomized Registry for the Evaluation of Sialendoscopy in the Diagnosis and Management of Sialolithiasis and Chronic Sialadenitis
Principal Investigator: Christopher Larsen, MD  

PROSPECTIVE Monitoring Juvenile Onset Recurrent Respiratory Papillomatosis - A Multicenter CDC Sponsored Registry
Principal Investigator: Daniel Bruegger, MD

Head and Neck Oncology

Patient Education and Satisfaction in Free Flap Surgery                
Principal Investigator: Kiran Kakarala, MD


At-Home Olfactory Training
Principal Investigator: Jennifer Villwock, MD

A Multicenter, Randomized, Double-Blind, Parallel-Group, Placebo-Controlled Phase 3 Efficacy and Safety Study of Benralizumab in Patients with Severe Nasal Polyposis (OSTRO)
Principal Investigator: David Beahm, MD

Last modified: Nov 07, 2019
Research Highlights

Click here for research highlights

Clinical Trial Registry