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Harrington Laboratory for Molecular Orthopedics


The Harrington Laboratory for Molecular Orthopedics
Department of Orthopedic Surgery 
The University of Kansas Medical Center
Mail Stop #3017, Smith East 4015
3901 Rainbow Boulevard
Kansas City, KS 66160
Tel: 913-588-0871 
Fax: 913-945-7773                                                                             


         Photo of Jinxi Wang at Microscope

Jinxi Wang, M.D., Ph.D
Harrington Distinguished Professor
Director, Harrington Laboratory for Molecular Orthopedics


The Harrington Laboratory for Molecular Orthopedics, directed by Dr. Jinxi Wang, was established in 2005. The name of this laboratory is in honor of Dr. Paul. R. Harrington's outstanding contributions to orthopedic research and in accordance with his wishes in the gift letter of the Mary Alice & Paul R. Harrington, MD, Distinguished Professorship Endowment. To learn more about Dr. Harrington (click here)

  This comprehensive laboratory consists of the following four research sections:

  1.     Molecular and Cell Biology
  2.     Histology
  3.     Biochemistry
  4.     In vivo Animal Studies   

The Laboratory occupies 2860 sq ft of laboratory and office space in the Smith East Building, accommodating the four research sections with relatively separate lab space for each section. Researchers in this laboratory study the regulatory mechanisms by which multipotent mesenchymal stem cells differentiate into osteoblasts (bone-forming cells), chondrocytes (cartilage-forming cells), or skeletal muscle cells. We also investigate the roles of specific signaling pathways (e.g. NFAT, integrin, and Wnt signaling pathways) in skeletal diseases and bone/cartilage regeneration. Our current projects are mainly focusing on the following research areas: (1) regulatory mechanisms of osteoblast differentiation and bone regeneration, (2) pathogenic mechanisms and novel therapeutics for osteoarthritis, and (3) molecular regulation of chondrocyte differentiation/function and articular cartilage regeneration.


 Wang lab member group pic in front of Smith 2016Wang lab members smith front 2106


Last modified: Jan 21, 2021