Sumedha Gunewardena, D.Phil
Research Assistant Professor
University of Oxford, 2005
Bioinformatics and computational genomics: modeling protein-DNA interactions, biological sequence analysis, microarray data analysis, biological pathways and network analysis, development of computational tools and databases.
Gunewardena S.S.A and Zhang, Z., “A Hybrid Model for Robust Detection of Transcription Factor Binding Sites", Bioinformatics (Jan. 2008) 24(4): 484-491.
Gunewardena S.S.A, Jeavons, P. and Zhang, Z., “Enhancing the Prediction of Transcription Factor Binding Sites by Incorporating Structural Properties and Nucleotide Co-Variations", Journal of Computational Biology (May 2006) 13(4): 929-945.
Gunewardena S.S.A and Zhang, Z., “Accounting For Physical properties And Nucleotide Polymorphisms in the Quantitative Prediction of DNA-protein Inter-actions", Paci¯c Symposium of Biocomputing (Jan. 2006).
Gunewardena S.S.A and Zhang, Z., “Finding Transcription Factor Binding Sites in DNA Sequences : A Template Based Approach.", In Proceedings of the 13th IEEE Workshop on Statistical Signal Processing (July 2005).
Huizhen Wang, Phillip Stevenson, Sumedha Gunewardena, and T. Rajendra Kumar. “Molecular Analysis of Testicular Defects in Fshb and Ccnd2 Double-Mutant Males.", Biology of Reproduction, July 2009, vol. 81.
Yue J. Cui, Sumedha S. Gunewardena and Curtis D. Klaassen. “Global Nuclear Occupancy of PXR and Co-existence of Histone H3k4 Di-methylation Resulting in Activation of Drug-processing Genes in Mouse Liver.", The 16th North American Regional ISSX Meeting, October 2009, Baltimore, MD.
Yue J. Cui, Sumedha S. Gunewardena and Curtis D. Klaassen., “Genome-wide Pro¯ling of PXR Reveals Unique DNA Binding Patterns and Co-existence of Distinct Epigenetic Signatures Resulting in Temporal Activation of Drug-Processing Genes and miRNAs in Mouse Liver." The 60th Annual Meeting of the American Association for the Study of Liver Diseases, October 2009, Boston, MA.