The following pilot funding opportunities are available to faculty researchers for the development of new projects. Proposals are reviewed by an external review committee who consider the significance and relevance of the proposed research to kidney physiology and disease, the validity and feasibility of the approach, the innovativeness of the project, the expertise of the investigator(s), and the likelihood that it will lead to an extramurally funded research project.
Racing Unlimited PKD Pilot Grants
The purpose of this grant is to support new basic science research on Polycystic Kidney Disease. Four grants have been awarded totaling $240,000 that provides $60,000 in funding for each research project. The Kidney Institute is grateful to Racing Unlimited in Idaho and all of the runners who participate in the Sawtooth Relay and the Zeitgeist Half Marathon for making these grants possible. The grant recipients and their project titles are:
- James Calvet, Ph.D. - "Calcium and cAMP Signaling Mechanisms in PKD"
- Xiaogang Li, Ph.D. - "The roles of heart polycystin-1 in ADPKD"
- Stephen Parnell, Ph.D. - "Does Polycystin-1 Reverse Cystogenesis?"
- Darren Wallace, Ph.D. - "The Role of B-Raf in Aberrant Cell Proliferation in PKD"
Kidney Institute Pilot Grants
The Kidney Institute provides pilot funds to investigators for the development of new projects in the field of kidney physiology, cell biology and translational research. Both basic science and clinical research projects are eligible for consideration. Investigators working in other areas are particularly encouraged to submit proposals to apply their expertise to problems related to kidney disease. Pilot projects are funded for one year with a total budget of up to $40,000. Past grant recipients and their project titles are:
- Pooja Budhiraja, M.D. - "Low Bioavailability Steroids for Treatment of Diarrhea Associated with Mycophenolate in Renal Transplant Recipients"
- Reena Rao, Ph.D. - "The Role of GSK3β in Tubular Repair and Development of Fibrosis Following AKI"
- Madhulika Sharma, Ph.D. - "The Role of Notch Signaling in Polycystic Kidney Disease"
- Darren Wallace, Ph.D. - "Targeting the LKB1-AMPK Pathway in Polycystic Kidney Disease"
- Stephen Parnell, Ph.D. - "Does Mutation L4132Δ Specifically Disrupt an Essential Signaling Function of Polycystin-1?"
- Madhulika Sharma, Ph.D. - "The role of Notch signaling in Polycystic Kidney Disease"
- Bhaskar Das, Ph.D. - "Boratinoid as novel therapeutic agent for treatment of polycystic kidney disease"
- Aditi Gupta, Ph.D. - "Cognitive impairment in end stage renal disease and its imaging correlates"
- Robin Maser, Ph.D. - "The Role of Polycystin-1 Biogenesis in Polycystic Kidney Disease"
- Stephen Parnell, Ph.D. - "Is mutation of a protein phosphatase-1 binding domain in polycystin-1 sufficient to cause PKD?"
- Katherine Swenson-Fields, Ph.D. - "Investigations into the pro-proliferative expression of WNT5A in ADPKD cyst cells using ADPKD cell lines."