Lynn S. Chollet Hinton, Ph.D., MSPH
Assistant Professor, Department of Biostatistics & Data Science
B.A., Biology, Grinnell College, Grinnell, IA
M.S.P.H., Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC
Ph.D., Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC
2018 - Michael S. O’Malley Alumni Award for Publication Excellence in Cancer Population Sciences, Lineberger Comprehensive Cancer Center, UNC Chapel Hill
2016 - Marci Kramish Campbell Dissertation Award, Lineberger Comprehensive Cancer Center, UNC Chapel Hill
2015-2017 - Predoctoral Fellowship, Cancer Control Education Program, Lineberger Comprehensive Cancer Center, UNC Chapel Hill
2014 - Best Poster Overall and Best Basic Research Poster Awards, Breast Cancer and the Environment Research Program (BCERP) Annual Meeting, San Francisco, CA
Associate Member, University of Kansas Cancer Center, Cancer Prevention & Control Program
Population health, epidemiology, biomarkers, electronic health records, administrative claims data, observational study design, missing data, categorical data analysis, survival analysis, longitudinal data, and data integration.
I am interested in multidisciplinary research that combines epidemiology, statistics, and biology with my passion for improving population health and patient outcomes. Much of my work focuses on the molecular epidemiology of cancer etiology and progression, integrating biomarker and clinical data with risk factor exposures and patient outcomes for a collaborative, holistic approach to cancer prevention and control research. My methodologic interests include addressing the challenges of observational studies, especially missing data and sources of bias in biomarker studies, as well as applying multivariate and mixed models to studies of population health. I am also interested in developing risk prediction models for breast cancer and other diseases to improve personalized screening and treatment efforts for high-risk patients. A fundamental goal for my research and teaching is to consider the underlying mechanisms of disease and the broader public health impact to ensure that my work as a data scientist is grounded in meaningful applications.
1. Chollet-Hinton L, Puvanesarajah S, Sandhu R, Kirk EL, Midkiff BR, Ghosh K, Brandt KR, Scott CG, Gierach GL, Sherman ME, Vachon CM, Troester MA. 2018. Stroma modifies relationships between risk factor exposure and age-related epithelial involution in benign breast. Mod Pathol 31:1085-1096. PMCID: PMC6076344.
2. Sun X, Shan Y, Li Q, Chollet-Hinton L, Kirk EL, Gierach GL, Troester MA. 2018. Intra-individual gene expression variability of histologically normal breast tissue. Sci Rep 8:9137. PMCID: PMC6002361.
3. Chollet-Hinton L, Olshan AF, Nichols HB, Anders CK, Lund JL, Allott EH, Bethea TN, Hong CC, Cohen SM, Khoury T, Zirpoli GR, Borges VF, Rosenberg LA, Bandera EV, Ambrosone CB, Palmer JR, Troester MA. 2017. Biology and etiology of young-onset breast cancers among premenopausal African American women: results from the AMBER Consortium. Cancer Epidemiol Biomarkers Prev 26:1722-1729. PMCID: PMC5903207.
*Featured as one of the National Cancer Institute's Epidemiology and Genomics Research Program (EGRP) Research Highlights for 2017 and Cancer Epidemiology, Biomarkers & Prevention's must-read paper of the month, December 2017.
**Winner of the Michael S. O'Malley Alumni Award for Publication Excellence in Cancer Population Sciences, Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill,
4. Chollet-Hinton L, Anders CK, Tse C, Bell MB, Yang YC, Carey LA, Olshan AF, Troester MA. 2016. Breast cancer biologic and etiologic heterogeneity by young age and menopausal status in the Carolina Breast Cancer Study: a case-control study. Breast Cancer Research 18:79. PMCID: PMC4972943.
5. Sandhu R*, Chollet-Hinton L*, Kirk EL, Midkiff B, Troester MA. 2016. Digital histologic analysis reveals morphometric patterns of age-related involution in breast epithelium and stroma. Human Pathology 48:60-68. PMCID: PMC4727830. *co-first authors
6. Chollet-Hinton L, Stuebe AM, Casbas-Hernandez P, Chetwynd E, and Troester MA. 2014. Temporal trends in the inflammatory cytokine profile of human breast milk. Breastfeeding Med 9:530-537. PMCID: PMC4267123.