KU School of Medicine-Wichita is located at 1010 N. Kansas, which is off of I-135 at the 8th/9th Street exit (Exit 7B). The Wichita campus is located just west of the Wichita-Sedgwick County Health Department at the intersection of Kansas Ave. and Minneapolis Ave.

The George J. Farha Medical Library is located on the first floor of the Wichita campus, just west of the main entrance.