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Radiology Clinical Trials

The Department of Radiology participates clinical trials. Learn about our upcoming, ongoing and previous clinical trials.

The Department of Radiology participates in other research activities, including the following clinical trials:

The following trials are open to enrollment:

  • #Hope4Liver: Evaluating the efficacy and safety of the HistoSonics System for the treatment of primary or metastatic tumors located in the liver.
  • SELECT 2: A Randomized Controlled Trial to Optimize Patient's Selection for Endovascular Treatment in Acute Ischemic Stroke
  • Pain Relief with GVE: Quantification of Pain Relief with Gonadal Vein Embolization for Pelvic Congestion Syndrome
  • ASSIST:  ASSIST registry's Purpose is to Assess the Procedural Success and Clinical Outcomes Associated With Various Operator Techniques for Mechanical Thrombectomy in Large Vessel Occlusions (LVO)
  • JETi Registry: JETi registry's purpose is to evaluate real-world patient outcomes after treatment of acute and non-acute upper and lower extremity venous and arterial thrombosis with the JETi Thrombectomy System.
  • Safety and efficacy of thrombectomy in combination with endhole aspiration in the treatment of acute DVT to demonstrate the effectiveness of venous thrombectomy combined with the endhole aspiration (Penumbra Indigo) in the single-session treatment of acute DVT.
  • Novel hypoxia imaging for Head and Neck Cancer: Imaging phenotype for personalized treatment. The purpose is to determine hypoxia imaging phenotype on the multi-modal PDB (perfusion, diffusion, and BOLD) MR imaging will predict which patients will respond to chemoradiotherapy.

The following trials are coming soon:

  • Ascelia Sparkle: A Multicentre, Open-label Study to Evaluate the Safety and Diagnostic Efficacy of Mangoral in Patients with Known or Suspected Focal Liver Lesions and Severe Renal Impairment
  • DOORwaY90: A prospective, multicenter, open-label single-arm study evaluating the safety and efficacy of selective internal radiation therapy (SIRT) using SIR-Spheres® Y-90 resin microspheres on duration of response (DoR) and objective response rate (ORR) in unresectable hepatocellular carcinoma (HCC) patients.
  • STRIKE-PE: A Prospective, Multicenter Study of the IndigoTM Aspiration System Seeking to Evaluate the Long-Term Safety and Outcomes of Treating Pulmonary Embolism.
  • Inari CLOUT: The primary objective of this study is to evaluate real-world patient outcomes after treatment of acute, subacute, and chronic proximal lower extremity deep venous thrombosis (DVT) with the ClotTriever Thrombectomy System.

The following trials are now closed to enrollment:

  • Utilizing 3D printing to assist planning of endovascular procedures in interventional radiology
  • International Acute Ischemic Stroke Registry with the Penumbra System Aspiration including the 3D Revascularization Device (COMPLETE Registry)
  • A Prospective, Multicenter Trial to Evaluate the Safety and Efficacy of the Indigo Aspiration System in Acute Pulmonary Embolism (EXTRACT-PE)
  • A Prospective, Multicenter Registry Assessing the Embolization of Neurovascular Lesions using the Penumbra SMART Coil System (SMART)
  • Yttrium Y-90 Resin Microspheres Data Collection in Unresectable Liver Cancer (RESIN Registry)
  • Abbreviated Breast MRI and Digital Tomosynthesis Mammography in Screening Women With Dense Breasts (EA1141)
  • TIPS Elastography: Shear Wave Elastography Assessment of Spleen Stiffness Before and After Transjugular Intrahepatic Portosystemic Shunt (TIPS) Procedure 
  • TCOM vs NIRS: Accuracy of Transcutaneous Oxygen Monitoring (TCOM) vs Near Infrared Spectroscopy (NIRS) in predicting wound outcomes in patients treated with or without revascularization
  • Investigational Diffusion-weighted Magnetic Resonance Imaging (MRI) of the breast. The purpose is to create a registry of participants undergoing investigational diffusion-weighted imaging (DWI) sequences with the purpose of improving breast MRI.
  • MONARCH: The primary objective of this study is to evaluate the performance and safety of the CaterpillarTM Arterial Embolization Device when used for arterial embolization in the peripheral vasculature in a real-world, on-label application.
KU School of Medicine

University of Kansas Medical Center
Radiology
Mail Stop 4032
3901 Rainbow Boulevard
Kansas City, KS 66160