Cecilia (Steffie) Villanueva
I earned my B.S. degree in Microbiology from The University of Kansas-Lawrence in 2018. In May of 2018, I joined the IGPBS program at The University of Kansas Medical Center and joined Dr. Hagenbuch’s Lab in December of 2019.
Human hepatocytes contain many transporters that are vital for the uptake of various compounds like bile acids, hormones, and drugs (i.e. statins). Organic Anion Transporting Polypeptides 1B1 and 1B3 (OATP1B1 & OATP1B3) are two specific uptake transporters that I am interested in. I am currently studying how S-palmitoylation, a reversible posttranslational modification that results in the addition of a fatty acid (palmitate) to cysteine resides on proteins, impacts OATP1B1 and OATP1B3 function and expression.