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Publications

X. Long Zheng, MD, PhD

Selected Publications

  1. Zheng L., Zhang D., Cao W.J., Song W.C., and Zheng X.L. Synergistic effects of severe ADAMTS13 deficiency and complement activation in pathogenesis of thrombotic microangiopathy in mice. Blood 2019 Sep 26;134(13):1095-1105. doi: 10.1182/blood.2019001040. PMID: 31409673.
  2. Sui J., Cao W.J., Halkidis K., Abdelgawwad M., Kocher N.K., Ganguraju R., Guillory B., Williams L.A., Marques M.B., and Zheng X.L. Longitudinal Assessments of Plasma ADAMTS13 Biomarkers Predict Recurrence of Immune Thrombotic Thrombocytopenic Purpura Blood Adv. 2019 Dec 23;3(24):4177-4186. doi: 10.1182/bloodadvances.2019000939. PMID: 31856267
  3. Zheng L. Abdelgawwad M.S., Zhang D., Xu L., Wei S., Cao W.J., and Zheng X.L. Histone-Induced TTP in Zebrafish Depends on Endothelial von Willebrand Factor. Haematologica 2020 Apr;105(4):1107-1119. doi: 10.3324/haematol.2019.237396. Epub 2019 Nov 21.
  4. Cao W.P., Cao W.J., Zhang W., Zheng X.L., (corr. Author), and Zhang X.H. Factor VIII binding affects the mechanical unraveling of the A2 domain of von Willebrand factor.  J Thromb Haemost. 2020 Sep;18(9):2169-2176. doi: 10.1111/jth.14962. Epub 2020 Jul 23. PMID: 32544272
  5. Zheng X.L., Vesley S., Cataland S, et al. ISTH Guidelines for the Diagnosis of Thrombotic Thrombocytopenic Purpura. J Thromb Haemost. 2020 Oct;18(10):2486-2495. doi: 10.1111/jth.15006. Epub 2020 Sep 11. PMID: 32914582
  6. Zheng X.L., Vesley S., Cataland S, et al. ISTH Guidelines for Treatment of Thrombotic Thrombocytopenic Purpura. J Thromb Haemost. 2020 Oct;18(10):2496-2502. doi: 10.1111/jth.15010. Epub 2020 Sep 11. PMID: 32914526
  7. Zheng X.L., Vesley S., Cataland S, et al. Good Practice Statements for the Clinical Care of Patients with Thrombotic Thrombocytopenia Purpura. J Thromb Haemost. 2020 Oct;18(10):2503-2512. doi: 10.1111/jth.15009. Epub 2020 Sep 11. PMID: 32914535
  8. Lu R, Sui J, Zheng XL. Elevated plasma levels of syndecan-1 and soluble thrombomodulin predict adverse outcomes in thrombotic thrombocytopenic purpura. J Thromb Haemost. 2020 Nov 10;4(21):5378-5388. doi: 10.1182/bloodadvances.2020003065. PMID: 33141886
  9. Basu MK, Massicano F, Yu L, Halkidis K, Pillai V, Cao W, Zheng L, Zheng XL. Thromb Haemost. 2021 Apr;121(4):506-517. doi: 10.1055/s-0040-1719030. Epub 2020 Nov 12.PMID: 33184803.
  10. Sui J, Lu R, Halkidis K, Kocher NK, Cao W, Marques MB, Zheng XL. Plasma levels of S100A8/A9, histone/DNA complexes, and cell-free DNA predict adverse outcomes of immune thrombotic thrombocytopenic purpura. J Thromb Haemost. 2021 Feb;19(2):370-379. doi: 10.1111/jth.15176. Epub 2021 Jan 3. PMID: 33188723
  11. Memon R, Sui J, Lin C, Zheng XL. Cerebral Infarction in Immune Thrombotic Thrombocytopenic Purpura Is Associated with Old Age, Hypertension, Smoking, and Anti-ADAMTS13 Ig, But Not with Mortality. TH Open. 2021 Jan 13;5(1):e1-e7. doi: 10.1055/s-0040-1722610. eCollection 2021 Jan. PMID: 33458563.
  12. Lin C, Memon R, Sui J, and Zheng XL. Identification of Biomarkers in Patients with Thrombotic Thrombocytopenic Purpura Presenting with Large and Small Ischemic Strokes. Cerebrovas Dis Extra. 2021;11:29–36. DOI: 10.1159/000513574. PMID: 33601375
  13. Halkidis K, Siegel DL, Zheng XL. A human monoclonal antibody against the distal carboxyl terminus of ADAMTS-13 modulates its susceptibility to an inhibitor in thrombotic thrombocytopenic purpura. J Thromb Haemost. 2021 Apr 9.  doi: 10.1111/jth.15332.  Online ahead of print. PMID: 33834592. 
  14. Lu R, and Zheng XL. Plasma levels of bigEndothelin-1 are associated with renal insufficiency and in-hospital mortality of immune thrombotic thrombocytopenic purpura. Thromb Haemost. 2021 May 13. doi: 10.1055/a-1508-8347. Online ahead of print. PMID: 33984867
  15. Zheng XL. The standard of care for immune thrombotic thrombocytopenic purpura today. J Thromb Haemost. 01 June 2021. https://doi.org/10.1111/jth.15406.

PubMed Publications

KU School of Medicine

University of Kansas Medical Center
Department of Pathology & Laboratory Medicine
Mail Stop 3045
3901 Rainbow Boulevard
Kansas City, KS 66160
Phone: 913-588-7070
Fax: 913-588-7073