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Harrington Lab

Recent Publications

  1. Jadalannagari S, Converse G, McFall C, Buse E , Filla M, Villar MT, Artigues A, Mellot  AJ, Wang J, Detamore MS, Hopkins RA, Aljitawi OS.  Decellularized Wharton's Jelly from human umbilical cord as a novel 3D scaffolding material for tissue engineering applications. PLOS ONE 2017; PMID:28222169 abstract  full text
  2. Townsend JM, Dennis SC, Whitlow J, Feng Y, Wang J, Andrews B, Nudo RJ, Detamore MS, Berkland  CJ.     Colloidal gels with extracellular matrix particles and growth factors for bone regeneration in critical size rat calvarial defects. AAPS J (American Association of Pharmaceutical Scientists Journal) 2017; PMID:28138909  abstract  full text
  3. Birt MC, Anderson DW, Toby EB, Wang J. Osteomyelitis: Recent advances in pathophysiology and therapeutic strategies. J Orthop 2017; 14:45-52. PMID: 27822001. PMCID: PMC5090239. abstract  full text      
  4. Feng Y, Egan B, Wang J. Genetic factors in intervertebral disc degeneration. Genes and Diseases 2016; 3:178-185. PMID: 27617275. PMCID: PMC5016799. abstract  full text
  5. Zhang M, Lu Q, Egan B, Zhong XB, Brandt K, Wang J. Epigenetically mediated spontaneous reduction of NFAT1 expression causes imbalanced metabolic activities of articular chondrocytes in aged mice. Osteoarthritis & Cartilage 2016; 24:1274-83. PMID: 26903200. PMCID: PMC4907852. abstract  full text
  6. Zhang M, Lu Q, Miller AH, Barnthouse NC, Wang J.  Dynamic epigenetic mechanisms regulate age-dependent SOX9 expression in mouse articular cartilage. Int J Biochem Cell Biol 2016; 72:125-34. PMID: 26806292.  PMCID: PMC4762732. abstract  full text
  7. Zhang M, Egan B, Wang J. Epigenetic mechanisms underlying the aberrant catabolic and anabolic activities of osteoarthritic chondrocytes. Int J Biochem Cell Biol 2015; 67:101-109.  PMID: 25975825. PMCID: PMC4564332. abstract  full text
  8. Zhang M, Wang J. Epigenetics and osteoarthritis. Genes & Diseases 2015; 2:69-75. PMID: 25961070. PMCID: PMC4421878. abstract  full text
  9. Caldwell KL, Wang J. Cell-based articular cartilage repair: the link between development   and regeneration. Osteoarthritis & Cartilage 2015; 23:351-62. PMID: 25450846. PMCID: PMC4339504 abstract  full text
  10. Blalock D, Miller A, Tilley M, Wang J. Joint instability and osteoarthritis. Clin Med Insights: Arthritis Musculoskelet Disord 2015; 8:15-23.  PMID: 25741184. PMCID: PMC4337591  abstract  full text
  11. Kruger TE, Miller AH, Godwin A, Wang J. (2014) Bone sialoprotein and osteopontin in bone metastasis of osteotropic cancers. Crit Rev Oncol Hematol 89:330-41.       PMID: 24071501. PMCID: PMC3946954  abstract  full text
  12. Kruger TE, Miller AH, Wang J. (2013) Collagen scaffolds in bone sialoprotein-mediated bone regeneration. Scientific World J  2013:1-6. doi:10.1155/2013/812718. PMID: 23653530. PMCID: PMC3628497 abstract  full text
  13. Nahar NN, Tague SE, Wang J, Danley M, Garimella R, Anderson HC. (2013)  Histological characterization of bone marrow in ectopic bone, induced by devitalized Saos-2 human osteosarcoma cells. Int J Clin Exp Med 6:119-25. PMID: 23386915. PMCID: PMC3560492 abstract  full text 
  14. Kramer WC, Hendricks KJ, Wang J. (2011) Pathogenetic mechanisms of posttraumatic osteoarthritis: opportunities for early intervention. Int J Clin Exp Med 4:285-98. PMID: 22140600. PMCID: PMC3228584  abstract  full text
  15. Rodova M, Lu Q, Li Y, Woodbury BG, Crist JD, Gardner BM,Yost JG, Zhong XB, Anderson HC, Wang J. (2011)  Nfat1 regulates adult articular chondrocyte function through its age-dependent expression mediated by epigenetic histone methylation. J Bone and Miner Res 26:1974-86. PMID: 21452283. PMCID: PMC3353550  abstract  full text
  16. Schroeppel JP, Crist JD, Anderson HC, Wang J. (2011) Molecular regulation of articular chondrocyte function and its significance in osteoarthritis. Histol Histopathol: Cell & Mol Biol 26:377-94. PMID: 21210351. abstract  full text
  17. Hofstaetter JG, Wang J, Hofstaetter SG, Glimcher MJ. (2010) The effects of high-dose, long-term alendronate treatment on microarchitecture and bone mineral density of compact and trabecular bone in the proximal femur of adult male rabbits. Arch Orthop Trauma Surg 130:937-44. PMID: 20490521. abstract  full text
  18. Wang Q, Wang J, Lu Q, Detamore MS, Berkland C. (2010) Injectable PLGA based colloidal gels for zero-order dexamethasone release in cranial defects. Biomaterials 31:4980-86. PMID: 20303585. PMCID: PMC2856787  abstract  full text
  19. Wang J, Gardner BM, Lu Q, Rodova M, Woodbury BG, Yost JG, Roby KF, Pinson DM, Tawfik O, Anderson HC (2009) Transcription factor NFAT1 deficiency causes osteoarthritis through dysfunction of adult articular chondrocytes. J Pathol 219:163-172.  PMID: 19526482. PMCID: PMC2975457  abstract   full text      
  20. Hofstaetter JG, Wang J, Yan J, Glimcher MJ (2009) The effects of alendronate in the treatment of experimental osteonecrosis of the hip in adult rabbits. Osteoarthritis Cartilage 17:362-70. PMID: 18786840.  abstract  full text
  21. Garimella R, Tague S, Zhang J, Belibi F, Nahar N, Sun B, Insogna K, Wang J, Anderson HC (2008) Expression and synthesis of bone morphogenetic proteins by osteoclasts: A possible path to anabolic bone remodeling. J Histochem Cytochem 56:569-77. PMID: 18319273.  abstract  full text
  22. Garimella R, Kacena M, Tague S, Wang J, Horowitz M, Anderson HC. (2007) Expression of bone morphogenetic proteins and their receptors in the bone marrow megakaryocytes of GATA-1low mice: A possible role in osteosclerosis. J Histochem Cytochem 55:745-52. PMID: 17371937.  abstract  full text
  23. Xu L, Anderson AL, Lu Q, Wang J. (2007) Role of fibrillar structure of collagenous carrier in bone sialoprotein-mediated matrix mineralization and osteoblast differentiation. Biomaterials 28:750-761. PMID: 17045334.  abstract  full text
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