Current Sleep Disorder Trials

Pharmaceutical Studies

Avadel

A Double-blind, Placebo-controlled, Randomized Withdrawal, Multicenter Study of the Efficacy and Safety of FT218 in the Treatment of Idiopathic Hypersomnia (IH)

Status: Open
Study Type: Interventional
Sponsor: Avadel
NCT06525077
PI: Damien Stevens

Inspire High AHI/BMI

Collecting long term information about the Inspire Upper Airway Stimulation in individuals with high BMI and AHI.

Enrollment Status: Enrolling
Study Type: Interventional
Sponsor: Inspire Medical Systems Inc.
NCT02413970
PI: Damien Stevens

Federally Funded Studies

RECOVER SLEEP

Platform Protocol for Evaluation of Interventions for Sleep Disturbances in Post-Acute Sequelae of SARS-CoV-2 Infection (PASC)

Enrollment Status: Enrolling
Study Type: Interventional
Sponsor: NIH
NCT06404086
PI: Damien Stevens / Diego Mazzotti

ENNVISA

Multi-night home sleep study looking how to improve our understanding of how sleep and breathing patterns vary from night to night in individuals with obstructive sleep apnea.

Enrollment Status: Enrolling
Study Type: Observational
Sponsor: NIH
PI: Diego Mazzotti

Investigator-Initiated Trials

SAGIC CVD

Observational study from the Sleep Apnea Global Interdisciplinary Consortium (SAGIC) evaluating blood pressure and heart rate variability changes before and after initiating continuous positive airway pressure (CPAP) of individuals using a 24-hour blood pressure monitor.

Enrollment Status: Open
Study Type: Observational
Sponsor: Investigator-Initiated
PI: Diego Mazzotti

SAGIC OSA Subtype Stability

Surveys collected to learn whether obstructive sleep apnea symptom subtypes are stable over the course of 3 weeks.

Enrollment Status: Open
Study Type: Observational
Sponsor: Investigator-Initiated
PI: Diego Mazzotti

OSA and Weight Loss

Study evaluating the combination of CPAP Therapy and Weight Loss Intervention

Enrollment Status: Paused
Study Type: Interventional
Sponsor: Lied Pre-Clinical Grants and the Clinical/Population Health Pilot
PI: Diego Mazzotti