Past Formal Seminars
Spring 2024
Speakers and Titles to be announced.
|
Date |
Time |
Speaker & Host |
Title |
Format |
|---|---|---|---|---|
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Jan 5 |
11:00 a.m. |
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Jan 12 |
11:00 a.m. |
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Jan 19 |
11:00 a.m. |
Dr. Robert Tarran, Chief, new Division of Genetic, Environmental and Inhalational Disease in the Department of Internal Medicine invited by Dr. Chad Slawson. |
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In-person |
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Jan 26 |
11:00 a.m. |
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Feb 2 |
11:00 a.m. |
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Feb 9 |
11:00 a.m. |
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Feb 16 |
11:00 a.m. |
Dr. Carlos Castañeda, Associate Professor |
UBQLN Phase Transitions in Protein Quality Control and Neurodegenerative Diseases |
In-Person |
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Feb 23 |
11:00 a.m. |
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March 1 |
11:00 a.m. |
Spencer Thompson, M.D./Ph.D. Student in the Freudenthal Lab, Department of Biochemistry and Molecular Biology, University of Kansas Medical Center invited by Dr. Christy Hagan
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Examining the protein scaffold XRCC1 in Base Excision Repair |
In-Person |
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March 8 |
11:00 a.m. |
No seminar due to Spring Break |
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March 15 |
11:00 a.m. |
No seminar due to Spring Break |
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March 22 |
11:00 a.m. |
No seminar due to Spring Break |
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March 29 |
11:00 a.m. |
Dr. Gary Meints, Professor, Department of Chemistry & Biochemistry, Missouri State University, invited by Dr. Bret D. Freudenthal. |
Damage Perturbs DNA Backbone Energetics: A Role in Repair Enzyme Recognition? |
In-Person |
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April 5 |
No seminar |
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April 12 |
Student Research Forum |
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April 19 |
11:00 a.m. |
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April 26 |
11:00 a.m. |
Dr. Julie Ostrander, Associate Professor of Medicine, Division of Hematology, Oncology and Transplantation, University of Minnesota, invited by Dr. Christy Hagan. |
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In-Person |
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May 3 |
11:00 a.m. |
Dr. David Ingham, Cryo-EM Specialist, Cryo-Electron Microscopy Facility, University of Kansas Medical Center, invited by Dr. Bret Freudenthal. |
Bringing Cryo-Electron Microscopy to KUMC |
In-Person |
|
May 10 |
11:00 a.m. |
Alexandra Berkowicz, Graduate Student, Department of Biochemistry and Molecular Biology, University of Kansas Medical Center, invited by Dr. Christy Hagan. |
Distinguishing Amyloid Variations with Innovative Biosensor Cells |
In-Person |
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May 17 |
11:00 a.m. |
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May 24 |
11:00 a.m. |
Dr. Merlin Nithya Gnanapragasam Assistant Professor, Center for Gene Regulation in Health and Disease (GRHD), Department of Biological, Geological, and Environmental Sciences, Cleveland State University, invited by Dr. Kenneth Peterson. |
In-Person |
Fall 2023
|
Date |
Time |
Speaker & Host |
Title |
Format |
|---|---|---|---|---|
|
August 25 |
11:00 a.m. |
Dr. Kristy A. Brown, Ph.D., Associate Professor of Metabolism and Cancer, Department of Cell Biology & Physiology, KUMC; Co-Program Leader, Cancer Prevention and Control, University of Kansas Cancer Center, invited by Dr. Bret Freudenthal. |
Obesity and Breast Cancer: Hungry for a Cure |
Hybrid |
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Sept 1 |
11:00 a.m. |
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Sept 8 |
11:00 a.m. |
Dr. Malay Busu, Associate Professor, Pathology and Laboratory Medicine, University of Kansas Medical Center, invited by Dr. Christy Hagan. |
Reading the book of life: the language of proteins |
Hybrid |
|
Sept 15 |
11:00 a.m. |
Reserved |
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Sept 22 |
11:00 a.m. |
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Sept 29 |
11:00 a.m. |
Dr. Vassilios Beglopoulos, Lecturer in Neuroscience |
Regulation of tau phosphorylation by the Alzheimer’s disease-implicated transcription factor REST in the adult mouse brain |
Zoom |
|
Oct 6 |
11:00 a.m. |
Dr. L. Caetano M. Antunes, Assistant Professor, Department of Molecular Biosciences, University of Kansas, invited by Dr. Christy Hagan. |
Modulation of enteric pathogen virulence by microbiome derived-small molecules |
In-Person |
|
Oct 13 |
11:00 a.m. |
Dr. Priyanka Verma, Assistant Professor, Department of Medicine, Oncology Division, Molecular Oncology, Washington University School of Medicine in St. Louis invited by Dr. Bret Freudenthal. |
Uncovering the tricks to treat BRCA-mutant cancers with PARP inhibitors |
In-Person |
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Oct 20 |
11:00 a.m. |
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Oct 27 |
11:00 a.m. |
Dr. Ryan Barnes, Assistant Professor, Cancer Biology, University of Kansas/Medical Center, invited by Dr. Bret Freudenthal. |
Oxidative and Replicative Stress at Telomeres and Beyond |
In-Person |
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Nov 3 |
11:00 a.m. |
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Nov 10 |
11:00 a.m. |
Dr. Tamir Gonen, Professor of Biological Chemistry and Physiology and HHMI Investigator, University of California Los Angeles |
Quo Vadis MicroED |
In-Person |
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Nov 17 |
2:00 p.m. |
Benjamin Ryan, Ph.D. Candidate, Dissertation Defense |
DNA Polymerase β: Mechanisms of Nucleotide Insertion During DNA Repair |
In-Person, Wahl Hall West 1006 |
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Nov 24 |
Thanksgiving-no seminar |
No seminar |
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Dec 1 |
11:00 a.m. |
Dr. Rosana Barreto Rocha Ferreira, Assistant Professor, Molecular Biosciences, University of Kansas invited by Dr. Christy Hagan. |
Searching for bioactive compounds produced by skin commensals |
In-Person |
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Dec 8 |
11:00 a.m. |
Dr. Mark Ranek, Assistant Professor, Department of Medicine, Division of Cardiology, Department of Pharmacology and Molecular Sciences, The Johns Hopkins Medical Institutions invited by Dr. Heather Wilkins. |
Chipping |
In-Person |
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Dec 15 |
11:00 a.m. |
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Spring 2023
|
Date |
Time |
Speaker & Host |
Title |
Format |
|---|---|---|---|---|
|
January 20 |
11:00 am |
Dr. Tonya Zeczycki, Ph.D., Assistant Professor, Department of Biochemistry and Molecular Biology, Eastern Carolina University, invited by Dr. Aron Fenton |
Bringing order to the chaos: understanding the roles intrinsic disorder, redox, and allostery have in regulating transglutaminase 2 |
Hybrid |
|
January 27 |
12 noon |
J. Brad Pesavento |
Cryo-EM |
1001-1003 Beller |
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February 3 |
11:00 am |
Dr. Meridith Hartley, Assistant Professor, Chemistry, University of Kansas, invited by Dr. Christy Hagan |
“Lipid dynamics during CNS myelin damage and repair” |
Hybrid |
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February 10 |
11:00 am |
Dr. Ann L. Wozniak, Assistant Professor, Gastroenterology, Hepatology and Motility, University of Kansas Medical Center, invited by Dr. Jeroen Roelofs. |
"Stress Granules and Cellular Trafficking" |
Hybrid |
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February 17 |
11:00 am |
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February 24 |
11:00 am |
Gabriel C. Lander, Scripps Research Institute |
"Do we still need crystallography? A case study in targeted protein degradation." Cryo-EM Seminar Series |
1001-1003 Beller |
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March 3 |
11:00 am |
Dr. Clarissa Durie, Assistant Professor, Department of Biochemistry, University of Missouri invited by Dr. Aron Fenton |
"Structure & Function of the Legionella pneumophila Dot/Icm Type IV Secretion System" Cryo-EM Seminar Series |
1001-1003 Beller |
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March 10 |
11:00 am |
No seminar due to Spring Break |
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March 13 |
11:00 am |
Michael S. Chapman, University of Missouri |
AAV cell entry by cryo-Electron Microscopy Cryo-EM Seminar Series |
1001-1003 Beller |
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March 17 |
11:00 am |
No seminar due to Spring Break |
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March 24 |
11:00 am |
No seminar due to Spring Break |
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March 28 |
11:00 am |
Yong Yu, St. John's University |
Contributions of Cryo-EM in understanding structure and function of polycystin ion channels Cryo-EM Seminar Series |
1001-1003 Beller |
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March 31 |
11:00 am |
Lauryn Werner, M.D./Ph.D. student thesis defense |
Progesterone Promotes Immunomodulation and Impacts Tumor Growth in the Murine Mammary Gland |
Hybrid |
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April 7 |
11:00 am |
No Seminar - Student Research Forum |
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April 14 |
11:00 am |
Kaitlin Dehart, Biochemistry graduate student |
Hybrid |
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April 21 |
11:00 am |
Taylor Strope, Biochemistry graduate student |
Hybrid |
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April 24 |
TBD |
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April 28 |
11:00 am |
Kaspar P. Locher, Institute of Molecular Biology and Biophysics |
High-resolution structure determination of membrane proteins using single-particle cryo-EM |
1001-1003 Beller |
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May 5 |
11:00 am |
Dr. Lezi E, Assistant Professor of Cell Biology, Department of Cell Biology, Neurobiology and Anatomy, Medical College of Wisconsin invited by Dr. Hao Zhu |
Hybrid |
Fall 2022
|
Date |
Time |
Speaker & Host |
Title |
Format |
|---|---|---|---|---|
|
August 26 |
11:00 a.m. |
Dr. Randal Halfmann, Associate Investigator, Stowers Institute for Medical Research |
Protein self-assembly governs cell fate |
Hybrid |
|
September 2 |
11:00 a.m. |
Dr. Ren Dobson, School of Biological Sciences University of Canterbury, New Zealand invited by Dr. Aron Fenton |
TRAPped in an elevator: amino-sugar uptake and utilisation by bacteria |
Zoom |
|
September 9 |
11:00 a.m. |
Dr. P. Hemachandra Reddy, Professor and Vice Chair Research of Basic and Translational Sciences, Texas Tech University Health Sciences Center, invited by Dr. Heather Wilkins. |
Oxidative Stress and Mitochondrial Dysfunction in Aging and Alzheimer’s Disease: Focus on Mitophagy Enhancers |
Zoom |
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September 16 |
No Seminar |
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September 23 |
11:00 a.m. |
Dr. Stephen D. Fried, Assistant Professor, Department of Chemistry, Johns Hopkins University, invited by Dr. Liskin Swint-Kruse |
A Proteome-wide Map of Chaperone-Assisted Protein Refolding in the Cellular Milieu |
Hybrid |
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September 30 |
11:00 a.m. |
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October 7 |
11:00 a.m. |
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October 14 |
11:00 a.m. |
Dr. Jared May, Assistant Professor, Division of Biological and Biomedical Systems, UMKC-School of Science and Engineering, invited by Dr. Christy Hagan |
Regulation of virus-host interactions by biomolecular condensates |
Hybrid |
|
October 21 |
11:00 a.m. |
Dr. Ross Marklein, Assistant Professor, School of Chemical, Materials, and Biomedical Engineering, College of Engineering, University of Georgia, invited by Dr. Heather Wilkins |
Development of advanced manufacturing approaches to understand and control mesenchymal stromal cell functional heterogeneity. |
Zoom |
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October 28 |
11:00 a.m. |
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November 4 |
11:00 a.m. |
Dr. Wagner Dias, Visiting Professor, Federal University of Rio de Janeiro, invited by Dr. Chad Slawson | Is O-GlcNAcylation important for tumor biology? | Hybrid |
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November 11 |
11:00 a.m. |
HUB-seminar |
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November 18 |
11:00 a.m. |
Dr. Andrea Mattevi, Department of Biochemistry and Molecular Biology, Universita Di Pavia, Italy, invited by Dr. Aron Fenton |
Structure and function of NADPH oxidases, the professional ROS generators |
Zoom |
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November 25 |
Thanksgiving - No seminar |
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December 2 |
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December 9 |
11:00 a.m. |
Dr. Anthony Fehr, Assistant Professor, Department of Molecular Biosciences, University of Kansas, invited by Dr. Christy Hagan |
ADP-ribosylation and its Impact on Coronavirus Infection |
Hybrid |
Spring 2022
| Date | Time | Speaker & Host | Title |
|---|---|---|---|
| January 21 | 11:00 am | Dr. Mark P. Farrell, Assistant Professor, Department of Medicinal Chemistry, University of Kansas, invited by Dr. Chad Slawson | Tackling the elephant in the immunotherapy room |
| January 28 | 11:00 am | Dr. Stefan Bossmann, Professor and Interim Chair, Department of Cancer Biology, University of Kansas Medical Center, invited by Dr. Liskin Swint-Kruse | The Evolution of Nanobiosensors for Protease Detection: Liquid Biopsies for Early Cancer Detection |
| February 4 | 11:00 am | Dr. Irina Tikhanovich, Assistant Professor, Department of Internal Medicine, University of Kansas Medical Center, invited by Dr. Christy Hagan. | Gender-specific role of lysine demethylases in alcohol-associated liver disease (ALD) |
| February 11 | 11:00 am | ||
| February 18 | 11:00 am | Dr. Zach Morris, Associate Professor, Dept. of Human Oncology, University of Wisconsin School of Medicine and Public Health, invited by Lauryn Werner. | Immunomodulating the tumor microenvironment using targeted radionuclide therapies to enhance response to immunotherapies |
| February 25 | 11:00 am | ||
| March 4 | 11:00 am | ||
| March 11 | 11:00 am | No Seminar - Spring Break | |
| March 18 | 11:00 am | Dr. Shizhen Jeff Wang, Assistant Professor, UMKC School of Biological and Chemical Sciences, invited by Dr. Lejla Zubcevic | Ligand and voltage gating of a human proton channel hHv1 |
| March 25 | 11:00 am | Dr. Nir Ben-Tal, Biochemistry and Molecular Biology, Tel Aviv University, invited by Dr. Alexey Ladokhin. | Protein archeology: How proteins emerged and evolve? |
| April 1 | 11:00 am | ||
| April 8 | 11:00 am | No Seminar - Student Research Forum | |
| April 15 | 11:00 am | Ibtihal Alghusen, Biochemistry and Molecular Biology Graduate Student | Regulation of mitophagy and mitochondrial stress response by O‐GlcNAc in Alzheimer's disease |
| April 22 | 11:00 am | Thesis Defense - Nicole Hoitsma | Characterizing AP-Endonuclease 1 (APE1) Cleavage of Diverse Biological Substrates |
| April 29 | 11:00 am | Shwetha Sreenivasan, Biochemistry and Molecular Biology Graduate Student | |
| May 5 | 11:00 am | ||
| May 6 | 11:00 am | Dr. Emma Morrison, Assistant Professor of Biochemistry, Medical College of Wisconsin, invited by Dr. Bret Freudenthal | Deciphering the dynamic language of histones |
| May 13 | 11:00 am | Sophiya John Ephrame, Biochemistry and Molecular Biology Graduate Student | |
| May 20 | 11:00 am | Appolinaire Olou, Sr. Research Associate, KUMC Cancer Biology, invited by Dr. Liskin Swint-Kruse | Investigating mechanisms of cellular stressors and their implication for pancreatic cancer progression |
Fall 2021
| Date | Time | Speaker | Title |
|---|---|---|---|
| August 27 | 11:00 a.m. | Dr. Michael Washburn, Professor, Department of Cancer Biology, University of Kansas Medical Center, invited by Dr. Aron Fenton | Integrated Structural Modeling of Chromatin Remodeling Complexes and Networks. |
| Sept 3 | 11:00 a.m. | Dr. David M. Smith, Associate Professor West Virginia University, invited by Dr. Jeroen Roelofs | Impairment of protein degradation by pathological oligomers associated with neurodegenerative disease. |
| Sept 10 | 11:00 a.m. | Dr. Daniel Bauer, Assistant Professor of Pediatrics at Harvard Medical School, invited by Dr. Ken Peterson | Genome editing to understand and treat blood disorders. |
| Sept 17 | 11:00 a.m. | ||
| Sept 24 | 11:00 a.m. | Dr. Kristy A. Brown, Associate Professor, Biochemistry in Medicine, Weill Cornell Medical College, invited by Dr. Christy Hagan | Hungry for a cure: Unacylated ghrelin inhibits the 3D growth of breast cancer cells. |
| Oct 1 | 11:00 a.m. | ||
| Oct 8 | 11:00 a.m. | Dr. Charles Sanders, Professor Vanderbilt University, Editor of Biochemistry, invited by Dr. Alexey Ladokhin | Ion Channel Super-Trafficking as A Disease Mechanism |
| Oct 15 | 11:00 a.m. | Dr. Long Zheng, Professor and Russell J. Eilers, MD Endowed Chair and Clinical Service Chief, Dept. of Pathology & Laboratory Medicine, University of Kansas Medical Center, invited by Dr. Antonio Artigues | ADAMTS and human diseases |
| Oct 22 | 11:00 a.m. | Dr. Konstantine Halkidis, Assistant Professor, The Division of Hematologic Malignancies and Cellular Therapeutics, Internal Medicine, The University of Kansas Medical Center, invited by Dr. Aron Fenton | The antibody-mediated pathophysiology of immune thrombotic thrombocytopenic purpura |
| Oct 29 | 11:00 a.m. | Dr. Peng Mao, Assistant Professor, Department of Internal Medicine, Division of Molecular Medicine, University of New Mexico Health Sciences, invited by Dr. Bret Freudenthal | BER in Chromatin: Genome-wide Mapping of Alkylation Damage and Repair |
| Nov 5 | 11:00 a.m. | ||
| Nov 12 | 11:00 a.m. | HUB- seminar | |
| Nov 19 | 11:00 a.m. | Dr. Mihaela Sardiu, Ph.D. Associate Professor at KUMC, Department of Biostatistics & Data Science invited by Dr. Alexey Ladokhin. | Looking at the Proteins from the "Top" |
| Nov 26 | Thanksgiving-no seminar | No seminar | |
| Dec 3 | 11:00 a.m. | Thesis Defense-Pierce O'Neil presented via Blackboard |
Membrane-induced refolding of tetanus neurotoxin translocation domain |
| Dec 10 | 11:00 a.m. |
Spring 2021
| Date | Time | Speaker & Host | Title |
|---|---|---|---|
| January 22 | 11:00 am |
Lance A. Johnson, Ph.D |
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| January 29 | 11:00 am | ||
| February 5 | 11:00 am | ||
| February 12 | 11:00 am | Olivia Veatch, Ph.D. University of Kansas Medical Center (hosted by Dr. Joseph Fontes) |
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| February 19 | 11:00 am | ||
| February 26 | 11:00 am | ||
| March 5 | 11:00 am | ||
| March 12 | 11:00 am | No Seminar - Spring Break | |
| March 19 | 11:00 am | Benjamin Ryan BMB Graduate Student |
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| March 26 | 11:00 am | Erin Young, Ph.D. Anesthesiology (hosted by Dr. Lejla Zubcevic) |
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| April 2 | 11:00 am | ||
| April 9 | 11:00 am | No Seminar - Student Research Forum | |
| April 16 | 11:00 am | Kyle Baumbauer, Ph.D Anatomy and Cell Biology (hosted by Dr. Lejla Zubcevic) |
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| April 23 | 11:00 am | Griffin Welfer BMB Graduate Student |
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| April 30 | 11:00 am | Lauryn Werner BMB Graduate Student |
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| May 7 | 11:00 am | Mandeep Kaur BMB Graduate Student |
Fall 2020
Fall 2020 seminars will be presented virtually
| Date | Time | Speaker & Host | Title |
|---|---|---|---|
| October 23 | 11:00 am |
Laurie Sanders, Ph.D. |
"Genome integrity in Parkinson's disease: From biomarker to mechanism" |
| October 30 | 11:00 am | ||
| November 6 | 11:00 am | Martin McCullagh, Ph.D. Oklahoma State University (hosted by Dr. Aron Fenton) |
"ATP Hydrolysis and Allostery in the Dengue Virus NS3" |
| November 13 | 11:00 am |
CANCELED |
|
| November 20 | 11:00 am | Benjamin Weaver, Ph.D. UT Southwestern Medical Center (hosted by Dr. James Calvet) |
"LIFE or DEATH....Caspases, it's in the way you use them" |
| November 27 | 11:00 am | No Seminar - Thanksgiving Holiday | |
| December 4 | 11:00 am | Lauren Porter, Ph.D. NIH/NLM/NCBI (hosted by Dr. Liskin Swint-Kruse) |
"Surveying the sequence landscape of fold-switching proteins" |
| December 11 | 11:00 am | Levi Wood, Ph.D. Georgia Tech (hosted by Dr. Heather Wilkins) |
" Systems Analysis of Neural Immune Signaling in Neurodegenerative Diseases" |
Spring 2020
| Date | Time | Speaker & Host | Title |
|---|---|---|---|
|
January 24 |
11:00 am |
Alexandria Cockrell, Graduate Student University of Kansas Medical Center |
"Exploring ribosomal DNA dynamics in fission yeast" |
|
January 31 |
11:00 am |
Lynne Dieckman, Ph.D. |
"Structure and Function of Proteins that Regulate Replication-Coupled Nucleosome Assembly" |
|
February 7 |
11:00 am |
Michael VanSaun, Ph.D. |
"Understanding mechanisms of obesity associated with pancreatic cancer progression" |
|
February 11 |
12 noon |
Malachi Griffith, Ph.D. |
"Immunogenomics approaches for development of cancer immunotherapies" |
|
February 21 |
11:00 am |
Mark Hedglin, Ph.D. |
"Mechanistic Insights into Human DNA Damage Tolerance from Fluorescence-based Studies" |
|
February 28 |
11:00 am |
Aaron R. Robert, Ph.D. |
"Mechanisms of Group II intron Splicing and Retrotransposition" |
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March 6 |
11:00 am |
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| March 13 |
11:00 am |
No Seminar - Spring Break | |
|
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Fall 2019
| Date | Time | Speaker & Host | Title |
|---|---|---|---|
|
September 20 |
11:00 am |
Heather Wilkins, Ph.D |
"Amyloid beta and bioenergetics" |
|
September 27* |
9:00 am |
Erica Golemis, Ph.D. |
"How studying PKD can provide insight into cancer biology" |
|
October 4 |
11:00 am |
Jeremy Schmit, Ph.D. |
"Biomolecule phase transitions: Universal behavior or specific functions" |
|
October 11 |
11:00 am |
S. Patricia Becerra, Ph.D. |
"A study of the biochemistry of proteins and its impact on medicine: PEDF and retina pathology" |
| October 25 |
11:00 am |
Kurt Piepenbrink, Ph.D. University of Nebraska (hosted by Dr. Aron Fenton) |
"Molecular Mechanisms of Motlility and Adhesion of Acinetobacter baumannii" |
| November 1 |
11:00 am |
Erik D. Holmstrom, Ph.D. University of Kansas - Lawrence (hosted by Dr. Christy Hagan) |
"Disordered RNA-folding chaperones promote nucleic acid conformational transitions via local charge screening" |
| November 22 |
11:00 am |
Brian Geisbrecht, Ph.D. |
"Evasion of the Complement/Neutrophil Axis by Staphylococcus aureus: A Biochemical Perspective" |
| December 13 |
11:00 am |
John Thyfault, Ph.D. University of Kansas Medical Center (hosted by Dr. Bret Freudenthal) |
"Pharmacotherapy and exercise interactions and implications for metabolic health" |
Spring 2019
| Date | Time | Speaker & Host | Title |
|---|---|---|---|
|
January 11 |
11:00 am |
Joshua Bembenek, Ph.D. University of Tennessee - Knoxville (hosted by Dr. Liskin Swint-Kruse) |
"Investigating mechanisms of cytokinesis during embryo development" |
|
January 18 |
11:00 am |
No Seminar |
|
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January 25 |
11:00 am |
Rebecca Wates, Ph.D. |
"Mitotic Kinesins as Therapeutic Targets in Cancer" |
|
February 1 |
11:00 am |
Changwei Liu, Ph.D. |
"Investigating functions of deubiquitinases USP9X and USP35" |
|
February 8 |
11:00 am |
Heng Du, Ph.D. |
"Molecular mechanisms of Alzheimer's disease: Mitochondrial biochemistry, Ghrelin receptor and Microglia-neuron crosstalk" |
|
February 15 |
11:00 am |
Blake Mertz, Ph.D. |
"Biophysics at the cellular interface: using simulations to understand an atypical membrane-active peptide" |
|
February 22 |
11:00 am |
Jeroen Roelofs, Ph.D. |
"The Life Cycle of a Proteasome; from assembly to degradation" |
|
March 1 |
11:00 am |
Erika R. Geisbrecht, Ph.D. |
"Metabolic defects promote pathogenesis in a muscular dystrophy model" |
|
March 8 |
11:00 am |
Nicole Ellis |
"Dissecting the Numerous Functions of |
|
March 15 |
11:00 am |
No Seminar - Spring Break |
|
|
March 26 |
10:00 am |
Lejla Zubcevic, Ph.D. |
"Mechanisms of TRPV ion channel gating" |
|
March 29 |
11:00 am |
Alan Tomkinson, Ph.D. |
"Insights into DNA ligase functions from small molecule inhibitors" |
|
April 5 |
11:00 am |
Max Fairlamb |
"Investigations into the Step-toStep Coordination |
|
April 12 |
11:00 am |
TBD |
|
|
April 19 |
11:00 am |
Minae Mure, Ph.D. University of Kansas - Lawrence (hosted by Dr. Christy Hagan) |
"Post-translational modifications of lysyl oxidase-like 2 and their effects on catalytic activity" |
| April 26 | 11:00 am | Anthony W. G. Burgett, Ph.D. University of Oklahoma (hosted by Dr. Aron Fenton) |
"Novel Anti-Viral and Precision Anti-Cancer Therapeutic Development Through Targeting the Oxysterol-binding Proteins (OSBP/ORPs)" |
| April 30* (no seminar May 3rd) |
12:00 noon Wahl Hall West Auditorium |
Michael Overholtzer, Ph.D. Sloan Kettering Institute co-sponsored with Cancer Center (Biochemistry host Dr. Chad Slawson) |
"Cell Death in Development and Disease" |
Fall 2018
| Date | Time | Speaker & Host | Title |
|---|---|---|---|
|
September 7 |
11:00 am |
Ming Xu, Ph.D. |
"Targeting cellular senescence to alleviate |
|
September 14 |
11:00 am |
Catherine Musselman, Ph.D. |
"The effect of nucleosome conformation on reader domain binding" |
|
September 21 |
11:00 am |
Stephen D. O'Connor, Ph.D. |
"Entrepreneurship in the Biomedical Field" |
|
September 28 |
11:00 am |
Kristi Neufeld, Ph.D. |
"Structure function study of colon tumor suppressor APC" |
|
October 5 |
11:00 am |
Shizhen 'Jeff' Wang, Ph.D |
"Ion Selectivity and Pore Gating: Insights from a Potassium Channel in Motion" |
|
October 12 |
11:00 am |
No Seminar - Faculty Research Day |
|
|
October 19 |
11:00 am |
Laird Forrest, Ph.D. |
"Development of localized cancer therapeutics" |
|
October 26 |
11:00 am |
Mary Markiewicz, Ph.D. |
"The multifaceted roles of NKG2D in autoimmune diabetes and cancer" |
|
November 2 |
11:00 am |
Blake Peterson, Ph.D. |
"Chemical Tools for Studies of Biological Systems" |
|
November 9 |
11:00 am |
Jodi Nunnari, Ph.D. |
"Mitochondrial Behavior" |
|
November 16 |
11:00 am |
Ewud Agborbesong, Graduate Student |
"Molecular insight into epigenetic regulation of cytokinesis and ciliogensis in ADPKD" |
|
November 23 |
11:00 am |
No Seminar - Thanksgiving Holiday |
|
|
November 30 |
11:00 am |
C. Michael Crowder |
"Hypoxic Injury is a Protein Synthesis and Folding Problem |
Spring 2018
| Date | Time | Speaker & Host | Title |
|---|---|---|---|
|
Jan. 19 |
11:00 am |
Jeffrey Thompson, Ph.D. |
"Assessing equivalent and inverse change in genomic data from multiple experiments: a new approach to functional analysis" |
|
Jan 26 |
11:00 am |
Benjamin Corb, Director of Public Affairs |
"Science Policy: Perspective from the Front Lines" |
|
Feb 16 |
11:00 am |
Mallory Smith |
"Molecular Insight into How Guanine Base Damage is Handled by DNA Polymerase beta " |
|
Feb 23 |
11:00 am |
Peter Harris, Ph.D. |
"The importance of posttranslational processing of polycystin-1 and fibrocystin to localization and function" |
|
Mar 2 |
11:00 am |
A. J. Mellott, Ph.D. |
"Orchestrating the Extracellular Environment to Induce Stem Cell Differentiation and Tissue Repair" |
|
Mar 9 |
11:00 am |
Matthew Schaich |
"Telomerase - an untapped cancer target" |
|
Mar 16 |
11:00 am |
John A. Hanover, Ph.D. |
"A Little Sugar Goes a Long Way: |
|
Mar 23 |
11:00 am |
No Seminar - Spring Break |
|
|
Mar 30 |
11:00 am |
Phillip E. Klebba, Ph.D. |
"Antibiotic discovery by fluorescence spectroscopic analyses of membrane transport in CRE/ESKAPE bacterial pathogens" |
|
Apr 6 |
11:00 am |
David Wilson, Ph.D. |
"Repair Mechanisms for Endogenous DNA Damage" |
|
Apr 13 |
11:00 am |
E. Matthew Morris, Ph.D. |
"Is Reduced Liver Energy Metabolism Making Us Obese" |
|
Apr 20 |
11:00 am |
Roberta Leonardi, Ph.D. |
" Regulation of coenzyme A and metabolic flexibility" |
|
Apr 27 |
11:00 am |
David Johnson, Ph.D. |
" The Computational Chemical Biology Core: Computational approaches for screening and design of small-molecule inhibitors" |
|
May 4 |
11:00 am |
Matthew Parker |
"Fine Tuning Hemoglobin Switching: Mechanisms at the Molecular Level" |
|
May 10* |
12:00 Noon |
Gerald A. Dienel, Ph.D. |
"Aerobic glycolysis during brain activation" |
|
May 11 |
11:00 am |
Michael Marvin, Ph.D. |
"SR Protein Kinase Phosphorylation & Splicing of Suboptimal Introns in Fission Yeast" |
|
May 18 |
11:00 am |
Steven D. Hartson, Ph.D. |
"Proteomic Profiling of Anti-cancer Drug Mechanisms" |
Fall 2017
| Date | Time | Speaker & Host | Title |
|---|---|---|---|
|
Sept 1 |
11:00 am |
Pierce O'Neil |
"Tetanus Neurotoxin: Unfolding the Refolding and Translocation Mechanism" |
|
Sept 8 |
11:00 am |
Michael S. Wolfe, Ph.D. |
"Gamma-Secretase and the Mechanism of Alzheimer's Disease" |
|
Sept 15 |
11:00 am |
Robert A. Harris, Ph.D. |
"Role of the PDK isoenzymes in glucose homeostasis, hepatic steatosis, and adipose tissue inflammation" |
|
Sept 22 |
11:00 am |
Julie Christianson, Ph.D. |
"The painful consequences of stress" |
|
Sept 29 |
11:00 am |
David Andrews, Ph.D. |
"Bcl-2 proteins regulate cell death at on and in membranes" |
|
Oct 6 |
11:00 am |
Scott Lovell, Ph.D. |
"A Protein Structure Medley: From Functional Studies to Inhibitor Development" |
|
Oct 13 |
11:00 am |
Wonpil Im, Ph.D. |
"Bacterial Outer Membranes and Interactions with Membrane Proteins" |
|
Oct 20 |
11:00 am |
Byron Caughey, Ph.D. |
"Prions, Amyloids and the transmissibility of protein misfolding diseases" |
|
Oct 27 |
11:00 am |
Amy Whitaker, Ph.D. |
"APE1 Cleavage Mechanisms during DNA Repair" |
|
Nov 3 |
11:00 am |
Olof Lagerlof, Ph.D. |
"O-GlcNAc: a new mechanism for how the brain controls food intake" |
|
Nov 10 |
11:00 am |
Thomas A. Kunkel, Ph.D. |
"Recent studies of nuclear DNA replication fidelity in budding yeast" |
|
Nov 17 |
11:00 am |
Irfan Saadi, Ph.D. |
"Genetic Dissection of SPECC1L Function in Craniofacial Morphogenesis" |
|
Nov 24 |
11:00 am |
No Seminar -Thanksgiving Holiday |
|
|
Dec 1 |
11:00 am |
Carla Koehler, Ph.D. |
"Pathways of RNA and protein import into mitochondria" |
|
Dec 8 |
11:00 am |
Joann Sweasy, Ph.D. |
"Base Excision Repair and Lupus" |
|
Dec 15 |
11:00 am |
Blaine Mooers, Ph.D. |
"Structural studies of RNA editing in trypanosomes" |
SPECIAL SEMINAR: June 23rd, 11 am, Lied Auditorium
Miguel Machuqueiro, PhD, Faculty of Sciences, University of Lisbon, Portugal
"Molecular Modeling pH effects in proteins: membrane interactions and drug binding"
SPRING 2017
| Date | Time | Speaker & Host | Title |
|---|---|---|---|
|
January 20 |
11:00 am |
Saurav Misra, Ph.D. |
"All that and a Bag of CHIPs - structure-function studies of cytoplasmic protein quality control" |
|
January 27 |
11:00 am |
Jay F. Storz, Ph.D. |
"Causes of parallel molecular adptation: insights from vertebrate hemoglobin" |
|
February 10 |
11:00 am |
Steven Roberts, Ph.D. |
"Landscape of APOBEC-induced mutation in Cancer" |
|
February 24 |
11:00 am |
Mario Rivera, Ph.D. |
"Bacterioferritin: Structure, dynamics and protein-protein interactions at play in iron storage and mobilization" |
|
March 3 |
11:00 am |
Kausik Si, Ph.D. |
"What memories are made of" |
|
March 10 |
11:00 am |
John J. Correia, Ph.D. |
"Biothermodynamics of Elastin-Like-Polypetides: the influence of drug labeling" |
|
March 17 |
11:00 am |
Joseph Fontes, Ph.D. |
"Modulation of the unfolded protein response by gap junctional coupling: hormetic mechanisms of neuronal death and survival" |
|
March 24 |
11:00 am |
No Seminar - Spring Break |
|
|
March 31 |
11:00 am |
Brian C. Freeman, Ph.D. |
"Molecular chaperones regulate the chromatin landscape. Is it time to move?" |
|
April 7 |
11:00 am |
No Seminar - Student Research Forum |
|
|
April 14 |
11:00 am |
Alexandra Machen, Graduate Student |
"Anthrax Toxin: the Unfolding Story of Structure and Function" |
|
April 21 |
11:00 am |
Luanne Peters, Ph.D. |
"Requirement for RASA3 in HSPC Differentiation: Studies in scat and Rasa3 cKO Models" |
|
April 28 |
11:00 am |
Danny R. Welch, Ph.D. |
"The forgotten genome: Surprising roles of mitochondriain cancer metastasis" |
|
May 5 |
11:00 am |
Shawn Burgess, Ph.D. |
"Fire and Ice: Mitochondrial Metabolism as a Mediator of Fatty Liver Disease" |
|
May 12 |
11:00 am |
John Thyfault, Ph.D. |
"Exercise, Aerobic Capacity, and impact on mitochondrial function in the liver" |
|
May 19 |
11:00 am |
Sarah Bondos, Ph.D. |
"Multiple structure-intrinsic disorder interactions regulate and coordinate Hox protein function" |
Fall 2016
| Date | Time | Speaker & Host | Title |
|---|---|---|---|
|
September 9 |
11:00 am |
Christopher J. Roberts, Ph.D |
"Mechanisms and Molecular Driving Forces for Aggregation of Therapeutic Proteins" |
|
September 23 |
11:00 am |
Todd Washington, Ph.D. |
"PCNA tool belts and polymerase bridges form during translation synthesis" |
|
October 7 |
11:00 am |
Hiroshi Nishimune, Ph.D. |
" Dual-color STED microscopy reveals synaptic structures of adult and aged mice" |
|
October 14 |
11:00 am |
Mathias Lösche, Ph.D |
" Regulation of the PTEN Tumor Suppressor: Insights from Scattering and MD studies" |
|
October 21 |
11:00 am |
Audrey Lamb, Ph.D. |
"Pyochelin biosynthesis: the enzymes from A to G" |
|
October 28 |
11:00 am |
Christopher Stipp, Ph.D. University of Iowa (hosted by Dr. Chad Slawson) |
"Alpha3 Beta1 Integrin is Abl to Help Hippo Inhibit Prostate Cancer Metastasis" |
|
November 4 |
11:00 am |
Grant Bullock, M.D., Ph.D., |
"The Role of Iron and Mitochondrial Metabolism in Erythropoiesis" |
|
Novermber 11 |
11:00 am |
Susan S. Taylor, Ph.D. |
"PKA: Assembly and Localization of Dynamic Macromolecular Signaling Complexes" |
|
November 18 |
11:00 am |
Victor Vasquez Montes, Graduate Student |
"Lipid-Dependent Modulation of Protein-Membrane Interactions" |
|
December 2 |
11:00 am |
Sefika Ozkan, Ph.D. |
"Allostery and Protein Dynamics in Evolution and Disease" |
|
December 9 |
11:00 am |
Ariel Bazzini, Ph.D. |
"Found in Translation |
|
December 16 |
11:00 am |
Randal Halfmann, Ph.D. |
"Quantitative Prion Biology" |
Spring 2016
| Date | Time | Speaker & Host | Title |
|---|---|---|---|
|
Jan 22 |
11:00 am |
Emad Tajkhorshid, Ph.D. |
"Visualizing Fuctional Motions of Biological Membranes and Membrane Proteins at Full Atomic Resolution Using Advanced Simulation Technologies |
|
Jan 29 |
11:00 am |
Qi Chen, Ph.D. |
"Vitamin C in cancer treatment: An unpaved journey" |
|
Feb 5 |
11:00 am |
Josephine Chandler, Ph.D. |
"Making friends to make war: bacterial quorum sensing, cooperation and interspecies competition" |
|
Feb 12 |
11:00 am |
Miles Pufall, Ph.D. |
"The androgen and glucocorticoid receptors use the same interface to bind functionally distinct DNA sequences" |
|
Feb 19 |
11:00 am |
Maria Kalamvoki, Ph.D. |
"Extracellular vesicles during Herpes Simplex Virus Infection" |
|
Feb 26 |
11:00 am |
Rick T. Dobrowsky, Ph.D. |
"Modulating the Chaperone to Treat Peripheral Neuropathies" |
|
Mar 4 |
11:00 am |
Patricia L. Opresko, Ph.D. |
"The impact of oxidative DNA damage on telomere maintenance and telomerase activity" |
|
Mar 11 |
11:00 am |
Sufi Thomas, Ph.D. |
"Targeting Tumor-stroma metabolic symbiosis for cancer therapy" |
|
Mar 25 |
11:00 am |
William E. Royer, Ph.D |
"regulation of Biological Activity through Protein Assembly: Conventional and Time-resolved Crystallographic Analyses of Cooperative Invertebrate Hemoglobins" |
|
Apr 8 |
11:00 am |
Katie Mitchell-Koch, Ph.D. |
"What can we learn about biomolecules with a little computational sleuthing?" |
|
Apr 15 |
11:00 am |
Marina Ramirez-Alvarado, Ph.D. |
"Light chain amyloidosis: Biophysics in the test tube and in the cell" |
|
Apr 22 |
11:00 am |
Marie Spies, Ph.D. |
"Single-molecule studies of FeS DNA helicases: kinetics, confrmation dynamics and molecular mechanisms" |
|
Apr 29 |
11:00 am |
Ilya Vakser, Ph.D. |
"Structural modeling of interactome" |
|
May 13 |
11:00 am |
Michael D. Brenowitz, Ph.D. |
"A new method of oxidative mapping of molecular interfaces" |
Fall 2015
| Date | Time | Speaker & Host | Title |
|---|---|---|---|
|
Sept 11 |
11:00 am |
Bryan Krantz, Ph.D. |
"Peptide and Proton Driven Allosteric Clamps Catalyze Anthrax Toxin Translocation across Membranes" |
|
Sept 18 |
11:00 am |
Christian Ray, Ph.D. |
"Lineage space and the propensity of cells to undergo growth transtions" |
|
Sept 25 |
11:00 am |
TBA |
TBA |
|
Oct 2 |
11:00 am |
CANCELED |
|
|
Oct 9 |
11:00 am |
TBA |
TBA |
|
Oct 16 |
11:00 am |
Ryan S. Funk, Pharm.D., Ph.D. |
"Identification of Biochemical Markers of Methotrexate Response in Juvenile Idiopathic Arthritis" |
|
Oct 23 |
11:00 am |
Prachee Avasthi, Ph.D. |
"Regulating the cell's antenna: novel trafficking and signaling mechanisms for ciliary assembly" |
|
Oct 30 |
11:00 am |
TBA |
TBA |
|
Nov 6 |
11:00 am |
Matt Cuneo, Ph.D. |
"A second allosteric switch in periplasmic binding protein mediated ABC transport" |
|
Nov 13* |
11:00 am |
James A. Wells, Ph.D |
"Drug Discovery at Challenging Targets: Reaching for High Hanging Fruit" |
|
Nov 20 |
11:00 am |
Laurie Steiner, MD |
"The histone methyltransferase Setd8 is critical for erythroblast survival and maturation" |
|
Nov 27 |
11:00 am |
No Seminar - Thanksgiving Holiday |
TBA |
|
Dec 4 |
11:00 am |
Jackie Thompson |
"The One-of-a-Kind Interaction between Phosphorylase Kinase and Its Substrate Glycogen Phosphorylase" |
|
Dec 11 |
11:00 am |
Ee Tan |
"The Sweet Side of Mitochondrial Regulation" |
|
Dec 18 |
11:00 am |
Eduardo Rosa-Molinar, Ph.D. |
"The Three Tenors: Electrical, Chemical, and Mixed Synapses" |
Spring 2015
Fall 2014
| Date | Time | Speaker & Host | Title |
|---|---|---|---|
|
Aug 29 |
11:00 am |
David B. Volkin, Ph.D. |
"New Analytical Approaches to Probe the Interrelationships between Protein Higher-Order Structure, Formulation Composition, and Pharmaceutical Stability" |
|
Sept 12 |
11:00 am |
Ralf Langen, Ph.D. |
"Membrane Remodeling by BAR and amyloid proteins in health and disease" |
|
Sept 19 |
11:00 am |
Gerald Hazelbauer, Ph.D. |
"Selective Allosteric Coupling of Transmembrane Signaling in Bacterial Chemotaxis" |
|
Sept 26 |
11:00 am |
Michael Wolfgang, Ph.D. |
"Fatty acid metabolism in the nervous system: nutrients and neurodegeneration" |
|
Oct 10 |
11:00 am |
Mary Markiewicz, Ph.D. |
"Novel Mouse Models Give New Insight into the Role of NKG2D and its Ligands in Immunity" |
|
Oct 17 |
11:00 am |
Karolin Luger, Ph.D. |
"Histone Chaperones in Transcription and DNA Repair: the usual and unusual suspects" |
|
Oct 24 |
11:00 am |
Tomoo Iwakuma, MD, Ph.D. |
"Targeting oncogenic mutant p53 cancer therapy" |
|
Oct 31 |
11:00 am |
Yana Bromberg, Ph.D. |
" The last straw did not break the camel's back: searching for causative variants of polygenic disease disregards individual predisposing genomic differences" |
|
Nov 7 |
11:00 am |
Mauricio Vargas Uribe, Graduate Student |
"pH-Triggered Membrane Insertion of Proteins" |
|
Nov 14 |
11:00 am |
Christine Jacobs-Wagner, Ph.D. |
"DNA Segregation in Bacteria" |
|
Nov 21* |
2:00 pm |
George R. Stark, Ph.D. |
"Novell Aspects of STAT and NFkB activation in Cancer" |
|
Nov 28 |
No Seminar - Thanksgiving Holiday |
||
|
Dec 5 |
11:00 am |
Jeffrey Bose, Ph.D. |
"The fatty acid kinase of Staphylococcus aureus regulates virulence" |
|
Dec 12 |
11:00 am |
Joanna Slusky, Ph.D. |
"The ins and outs of membrane proteins" |
|
Dec 19 |
11:00 am |
Jianhan Chen, Ph.D. |
"The Orderly Chaos of Proteins" |
Spring 2014
| Date | Time | Speaker & Host | Title |
|---|---|---|---|
|
Jan 17 |
11:00 am |
Christopher Ward, M.D., Ch.B., Ph.D. |
"Polycystic kidney diseases and exosomes" |
|
Jan 24 |
11:00 am |
William G. Gutheil, Ph.D. |
"Coping with complexity: a Hierarchical Interaction Approach, and its Application to Hemoglobin" |
|
Jan 31 |
11:00 am |
Samuel Bouyain, DPhil |
"Contactin/protein tyrosine phosphatase complexes in the nervous systems" |
|
Feb 7 |
11:00 am |
Jacob Schwartz, Ph.D. |
"An RNA-centric view of neurodegenerative disease" |
|
Feb 14 |
11:00 am |
Bret Freudenthal, Ph.D. |
"Breaking Bad: Watching a DNA polymerase make a mistake" |
|
Feb 21 |
11:00 am |
Ivan Babic, Ph.D. |
"Metabolic reprogramming in Brain Cancer Induced by Oncogenic EGFRvIII Expression" |
| Date | Time | Speaker & Host | Title |
|---|---|---|---|
|
Feb 28 |
11:00 am |
Christy Hagan, Ph.D. |
"Progesterone Signaling Drives Proliferative Transcriptional Programs in Breast Cancer" |
|
Mar 7 |
11:00 am |
Steven T. Whitten, Ph.D. |
"Structural characteristics of intrinsically disordered protein" |
|
Mar 14 |
11:00 am |
Jason Stewart, Ph.D |
"Maintaining Stability: Roles of the Human CST Complex in DNA Replication and Chromosome Cohesion" |
| Date | Time | Speaker & Host | Title |
|---|---|---|---|
|
Apr 11 |
11:00 am |
Tiangang Li, Ph.D. |
"Regulation of lipid metabolism in obesity and diabetes" |
|
Apr 18 |
11:00 am |
Bradley L. Pentelute, Ph.D. |
"Precision delivery of biologics into cells" |
|
Apr 25 |
11:00 am |
Rushi Trivedi, Graduate Student |
"SNF2 ATPase regulatory domains - functions & effects on chromatin remodeling and ATPase activity" |
|
May 2 |
11:00 am |
Vicente Notario, Ph.D. |
"Contribution of an enzymatically inactive protein to human tumor progression" |
|
May 9 |
11:00 am |
Ramesh Balusu, Ph.D. |
TBA |
FALL 2013
| Date | Time | Speaker & Host | Title |
|---|---|---|---|
|
Sept 13 |
11:00 am |
Bashkar Das, Ph.D. |
"Chemical Biology Approach to Identify Druggable Biomarkers and Develop Molecular Imaging and Therapeutics Agents" |
|
Sept 20 |
11:00 am |
Arindam Paul, Ph.D. |
"Atypical PKC Signaling and Breast Cancer" |
|
Oct 4 |
11:00 am |
Jeremy Chien, Ph.D. |
"Forward and Reverse Genetics to Identify Altered Molecular Pathway in Ovarian Cancer" |
|
Oct 11 |
11:00 am |
Costa P. Georgopoulos, Ph.D. |
"Regulation of the essential, universally-conserved GroEL/GroES (Hsp60/Hsp10) chaperone protein-folding machine" |
|
Oct 18 |
11:00 am |
David P. Giedroc, Ph.D. |
"A Double-Edged Sword: Transition Metal Chemistry at the Host-Microbial Pathogen Interface" |
|
Oct 25 |
11:00 am |
Xun Gu, Ph.D. |
"Functional divergence between duplicate genes" |
|
Nov 1 |
11:00 am |
T. Rajendra Kumar, Ph.D. |
"Genetics & Patho-physiology of Pituitary Null Cell Tumors" |
|
Nov 8 |
11:00 am |
Terry Graham, Ph.D. |
"Muscle glycogen: thoroughly studied but poorly understood" |
|
Nov 15* |
2:00 p.m. |
Michael A. Marletta, Ph.D. |
"Molecular Aspects of Gas Sensing" |
|
Nov 22 |
11:00 am |
Susan M. Egan, Ph.D. |
"Mechanisms and Inhibition of AraC Family Regulators of Virulence and Carbon Metabolism" |
|
Dec 6 |
11:00 am |
Joan Lewis-Wambi, Ph.D. |
"Paradoxical action of estrogen in aromatase-inhibitor resistant breast cancer cells" |
|
Dec 13 |
11:00 am |
Mukut Sharma, Ph.D. |
"Cytokines of the IL-6 Family and Chronic Kidney Disease" |
Spring 2013
| Date | Time | Speaker & Host | Title |
|---|---|---|---|
|
Feb 1 |
11:00 am |
Dan A. Dixon, Ph.D. |
"Regulation of RNA Stability in Colorectal Cancer" |
|
Feb 8 |
11:00 am |
Michele Pritchard, Ph.D. |
"Early growth response (Egr)-1: The Jekyll and Hyde of liver injury and repair" |
|
Feb 15 |
11:00 am |
Holly Ellis, Ph.D. |
"Investigation the Functional and Structural Oddities of Cysteine Dioxygenase" |
|
Feb 22 |
11:00 am |
Canceled due to inclement weather. |
|
|
Mar 1 |
11:00 am |
Ann Louise Olson, Ph.D. |
"A role for GLUT4 in the metabolic adaptation to diet induced obesity" |
|
Mar 8 |
11:00 am |
Preston Hensley |
"SomaLogic - A High Content Proteomics Technology to Accelerate Drug and Diagnostic Discovery" |
|
Mar 15 |
11:00 am |
Christopher J. Ward, M.B., Ch.B., Ph.D. |
"The exosome primary cilium interaction" |
|
Mar 22 |
11:00 am |
No Seminar - Spring Break |
|
|
Mar 29 |
11:00 am |
Shuai Lu |
"Cohesion Biology |
|
Apr 5 |
11:00 am |
On Hold for Student Research Forum |
|
|
Apr 12 |
11:00 am |
Canceled Speaker will reschedule in the Fall Semester |
|
|
Apr 19 |
11:00 am |
Severin Gudima, Ph.D. |
"Super-infection and virus spread continue during chronic hepadnavirus infection" |
|
Apr 26 |
11:00 am |
Dan Parente |
"Computational Strategies for Predicting the Functional Impact of Protein Polymorphisms" |
|
May 3 |
11:00 am |
Vargheese Chennathukuzhi, Ph.D |
"The loss of REST and the pathogenesis of uterine leiomyomas" |
|
May 10 |
11:00 am |
Luciano DiTacchio, Ph.D. |
"JARID1a at the intersection between the circadian clock and energy metabolism" |
|
May 17 |
11:00 am |
Lauren E. Ball, Ph.D. |
"Nutrient Sensitive O-GlcNAc Modification of Mediators of Insulin/Igf-1 Signaling" |
FALL 2012
| Date | Time | Speaker & Host | Title |
|---|---|---|---|
| Sept 7 | 11:00 am |
Eric J. Deeds, Ph.D. |
"The Dynamics of Assembly in Biological Networks" |
| Sept 14 | 11:00 am |
Donald Jacobs, Ph.D. |
"Interrelationships Between Protein Stability, Flexibility and Dynamics" |
| Sept 21 | 11:00 am |
Rajasingh Johnson, Ph.D., HCLD |
"Reprogramming of Somatic Cells and Therapy" |
| Sept 28 | 11:00 am |
Paul Sorgen, Ph.D. |
"Characterization of the Structure and Intermolecular Interactions between the Connexin32 Carboxyl-terminal Domain and the Protein Partners SAP97 and Calmodulin" |
| Oct 5 | 11:00 am |
Adam Krieg, Ph.D. |
" Hypoxic Regulation of Histone Demethylases Mediates Cellular Response to the Tumor Microenvironment" |
| Oct 12 | 11:00 am |
Xiaogang Li, Ph.D. |
"Epigenetic regulators and autosomal dominant polycystic kidney disease" |
| Oct 19 * | 11:00 am |
Andrew L. Lee, Ph.D. |
"Insights into mechanisms of protein allostery from dynamics and NMR" |
| Oct 26 | 11:00 am |
Fan Dong, M.D., Ph.D. |
"Towards understanding of Gfi1 acts in hematopoiesis; the significances of its interaction with Miz-1 and the mechanism of its down regulation by p53" |
| Nov 2 | 11:00 am |
Quyen Hoang, Ph.D. |
"Mechanisms of genetics and envrionmental toxins in Parkinson's disease" |
| Nov 9 * | 1:00 PM |
Heidi E. Hamm, Ph.D. |
"New insights into mechanisms of receptor-mediated G protein activation" |
| Nov 13 | 11:00 am |
James Bowie, Ph.D. |
"How do membrane proteins fold?" |
| Nov 16 | 11:00 am |
Elizabeth Komives, Ph.D. |
"Functional Consequences of Intrinsic Disorder in the NFkB-IkB Interaction" |
| Nov 23 | 11:00 am |
No Seminar - Thanksgiving Holiday |
|
| Nov 30 | 11:00 am |
Paul H. Axelsen, M.D. |
"Oxidative Stress, Lipid Membranes, and Protein Misfolding in Alzheimer's Disease" |
| Dec 7 | 11:00 am |
Brian S. J. Blagg, Ph.D. |
"Hsp90 inhibitors: past, present and future" |
| Dec 14 | 11:00 am |
Thomas M. Ryan, Ph.D. |
"Humanized Models of Beta Thalassemia Major & Taking the R out of RBC" |
Spring 2012
| Date | Time | Speaker & Host | Title |
|---|---|---|---|
| Jan 13 | 11:00 am | Heather Desaire, Ph.D. University of Kansas - Lawrence (hosted by Dr. Chad Slawson) |
"Enabling Technologies for Glycopeptide Analysis and Application to HIV vaccine development" |
| Jan 27 | 11:00 am |
Lu Chen |
"The combinatorial nature of building chromatin remodeling machineries" |
| Feb 10 | 11:00 am | Moriah Beck, Ph.D. Wichita State University (hosted by Dr. Liskin Swint-Kruse) |
"Structure and crosslinking mechanism of palladin's novel actin binding domain" |
| Feb 17 | 11:00 am | Subhash Naik Graduate Student - Biochemistry University of Kansas Medical Center |
"Proteostasis and the kinetic aspects of misfolding diseases" |
| Feb 24 | 11:00 am |
Alan S. L. Yu, MB, BChir. |
"Structure-function studies of claudins, tight junction membrane proteins that regulate paracellular permeability" |
| Mar 9 | 11:00 am | Christopher J. Fischer, Ph.D. University of Kansas - Lawrence (hosted by Dr. Mark Fisher) |
"Unravelling the kinetics of nucleosome repositioning" |
| Mar 16 | 11:00 am |
Jeroen Roelofs, Ph.D. |
"Mechanism of chaperone-assisted assembly of the proteasome regulatory particle" |
| Apr 6 | 11:00 am |
Michael Bulger, Ph.D. |
"Enhancers and Hyperactylated Domains in Erythroid-Specific Gene Loci" |
| Apr 13 | 11:00 am | Mingui Fu, Ph.D. University of Missouri - Kansas City (hosted by Dr. Joe Fontes) |
"Regulation of Inflammation and Immune Homeostasis by MCPIP1" |
| Apr 20 | 11:00 am | Patrick Frantom, Ph.D. University of Alabama (hosted by Dr. Aron Fenton) |
"Allosteric Regulation of alpha-Isopropylmalate Synthase from Mycobaterium tuberculosis by L-Leucine" |
| Apr 27 | 11:00 am | Bryce V. Plapp, Ph.D. University of Iowa (hosted by Dr. Fenton) |
"Alcohol dehydrogenase Dynamics and Catalysis" |
| May 4 | 11:00 am |
George Vielhauer, Pharm.D./Ph.D. |
"Development of C-terminal Hsp90 inhibitors for the treatment of cancer" |
| May 11 | 11:00 am | Maria Kurnikova, Ph.D. Carnegie Mellon University (hosted by Dr. Alexey Ladokhin) |
"Molecular Modeling of how structure facilitates function in membrane proteins" |
Fall 2011
| Date | Time | Speaker & Host | Title |
|---|---|---|---|
| Sept 9 | 11:00 am | Candice S. Klug, Ph.D. Medical College of Wisconsin (hosted by Dr. Alexey Ladokhin) |
"Effects of two key nucleotide binding domain mutations on the functional dynamics of the bacterial lipid flippase MsbA" |
| Sept 16 | 11:00 am | Qi Chen, Ph.D. University of Kansas Medical Center (hosted by Dr Liskin Swint-Kruse |
"Pro-oxidant vitamin C: a promising role in cancer treatment?" |
| Sept 30 | 11:00 am | Kelly Tatchell, Ph.D. Louisiana State University (hosted by Dr. Ken Peterson) |
"TOR Complex 2 regulates Lpl1/Autora B function via the GlcPP1 phosphatase" |
| Oct 7* | 11:00 am | Michael L. Gross, Ph.D. Washington University in St. Louis (hosted by Dr. Aron Fenton) |
"Applications of Mass-Spectrometry-Based Footprinting (H/DX and FPOP) to Aggregating Proteins) |
| Oct 21 | 11:00 am | Lesa J. Beamer, Ph.D. University of Missouri - Columbia (hosted by Dr. Swint-Kruse) |
"Connecting structure, dynamics, and conformation change to enzyme function: studies of bacterial phosphohexomutase" |
| Oct 28 | 11:00 am | Richard R. Burgess, Ph.D. University of Wisconsin - Madison (hosted by Dr. Mark Fisher) |
"One-second isolation/immunoprecipitation of weak protein complexes using a microfluidic IFAST device" |
| Nov 4 | 11:00 am | Judith Davie, Ph.D. Southern Illinois University School of Medicine (hosted by Dr. Joseph Fontes) |
"Deciphering the role of interferon gamma andCIITA in myogenesis" |
| Nov 11 | 11:00 am | CANCELED. Speaker rescheduled to March 9, 2012 | |
| Nov 18* | 11:00 am | Richard W. Hanson, Ph.D. Case Western Reserve University School of Medicine (hosted by Dr. Carlson) |
"Born to run; the story of the PEPCK-Cmus mouse" |
| Dec 2 | 11:00 am | Danny R. Welch, Ph.D. University of Kansas Medical Center (hosted by Dr. Gerald Carlson) |
"Metastasis Suppressors: Genetics, Epigenetics and the Tumor Microenvironment" |
| Dec 9 | 11:00 am | Gerald Hart, Ph.D. Johns Hopkins University School of Medicine (hosted by Dr. Chad Slawson) |
"Extensive Crosstalk Between Phosphorylation and O-GlcNAcylation: Critical Roles in Diabetes, Alzheimer's Disease and Cancer" |
| Dec 16 | 11:00 am | Junpeng Deng, Ph.D. Oklahoma State University (hosted by Dr. Aron Fenton) |
"IL18 and IL18BP in autoimmune and poxvirus infection" |
Spring 2011
| Date | Time | Speaker & Host | Title |
|---|---|---|---|
| Jan 14 | 11:00 am |
Andrew Herr, Ph.D. |
"Molecular basis for metal ion-induced intercellular adhesion in Staphylococcal biofilms" |
| Jan 21 | 11:00 am |
Gerald Wyckoff, Ph.D. |
"Bioinformatics and Evolution; A view from behind the monitor" |
| Jan 28 | 11:00 am | Colin Thorpe, Ph.D. University of Delaware (hosted by Dr. Mark Fisher) |
"Making Protein Disulfide Bonds - Oxidative Folding in a Muddle" |
| Feb 4 | 11:00 am | David D. Weis, Ph.D. University of Kansas - Lawrence (hosted by Dr. Aron Fenton and Dr. Antonio Artigues) |
"Investigation disordered proteins with D/D exchange and mass spectrometry" |
| Feb 18 | 11:00 am | Xiaolan Yao, Ph.D. University of Missouri - Kansas City (hosted by Dr. Alexey Ladokhin) |
"Estimation of available free energy in a LOV-Ja photoswitch" |
| Mar 4 | 11:00 am | Troy Johnson Graduate Student |
"PEPCK and catalysis: The fundamentals" |
| Mar 11 | 11:00 am | Christopher Vakoc, Ph.D. Cold Spring Harbor Laboratory (hosted by Dr. Kenneth Peterson) |
"Epigenetics of Malignant Hematopoiesis" |
| Mar 25 | 11:00 am | Alex Moise, Ph.D. University of Kansas - Lawrence (hosted by Dr. Todd Holyoak) |
"Identification of a novel retinoid-processing enzyme involved in the regulation of lipid metabolism" |
| Apr 1 | 11:00 am | Bin Deng, Graduate Student, Zhu lab | "Structural basis of inter-domain electron transfer in Ncb5or" |
|
Apr 8* |
11:00 am | John S. Olson, Ph.D.* Rice University (hosted by Dr. Swint-Kruse) NOTE: this seminar will be in 1027 Orr-Major |
"NO Dioxygenation Globin Evolution, and Recombinant Hb-based Blood Substitutes" |
| Apr 15 | 11:00 am | Anton A. Komar, Ph.D. Cleveland State University (hosted by Dr. Joseph Fontes) |
"Protein Folding on the Ribosome: When the Protein Folding Code Meets the Genetic Code" |
| Apr 22 | 11:00 am | Michael Baldwin, Ph.D. University of Missouri - Columbia (hosted by Dr. Mark Fisher) |
"Unique Ganglioside Recognition Strategies of Clostridial Neurotoxins" |
| Apr 29 | 11:00 am | David L. Bain, Ph.D. University of Colorado - Denver (hosted by Dr. Aron Fenton) |
"Towards a Quantitative Understanding of the Human Steroid Receptors: The Role of Energetics" |
| May 6* | 11:00 am | Xiuxia Du, Ph.D. University of North Carolina at Charlotte (hosted by Dr. Owen Nadeau) NOTE: this seminar will be in 1027 Orr Major |
"Xlink-Identifier: An Automated Data Analysis Platform for Confident Identifications of Chemically Cross-Linked Peptides Using Tandem Mass Spectrometry" |
| May 13 | 11:00 am |
Pablo Sobrado, Ph.D. |
"Mechanistic studies of UDP-galatopyranose mutases from eukaryotic human pathogens" |
Fall 2010
| Date | Time | Speaker & Host | Title |
|---|---|---|---|
| Sep 10 |
11:00 am
|
Jed N. Lampe, Ph.D. University of Kansas Medical Center (hosted by Dr. Mark Fisher) |
"Cytochrome P450 Protein-Ligand Interactions revealed through 2D MNR and Molecular Dynamic Simulations" |
| Sep 17 |
11:00 am
|
Lukas Tamm, Ph.D. |
"Reconstitution of SNARE mediated Fusion on the Millisecond Timescale" |
| Sep 24 |
11:00 am |
Christopher H. Lowrey, M.D. Dartmouth-Hitchcock Medical Center (hosted by Dr. Kenneth Peterson) |
"Pharmacologic Induction of Fetal Hemoglobin Via Cell Stress Signaling Pathways; What Doesn't Kill Red Cells May Make Them Stronger" |
| Oct 8 |
11:00 am
|
Gloria Borgstahl, Ph.D. University of Nebraska Medical Center (hosted by Dr. Swint-Kruse) |
"Identification of the DNA binding domains of Replication Protein A that recognize G-quadruplex DNA" |
| Oct 22 | 11:00 am | Please Note: Dr. David Weis' seminar has been canceled. It is rescheduled to Feb. 4, 2011. | |
| Oct 29 | 11:00 am | Hiroo Katayama Graduate Student Dept of Biochemistry and Molecular Biology |
"Anthrax toxin protective antigen: cell entry, transition to the pore, and translocation" |
| Nov 5 | 11:00 am |
Marie Trudel, Ph.D. |
"Signaling Mechanisms in Human ADPKD: Insights from Pkd1 Mouse Models" |
| Nov 12 | 11:00 am | James C. Lee, Ph.D. University of Texas Medical Branch (hosted by Dr. Aron Fenton) |
"Structural and Functional Landscapes in the Allosteric Regulation CRP" |
| Nov 19 | 11:00 am | Peter V. Cornish, Ph.D. University of Missouri - Columbia (hosted by Dr. Aron Fenton) |
"Single molecule investigation of ribosome dynamics and function" |
| Nov 26 | 11:00 am | No seminar - Thanksgiving Holiday | |
| Dec 3 | 11:00 am | Doug English, Ph.D. Wichita State University (hosted by Dr. Alexey Ladokhin) |
"Catanionic Surfactant Mixtures: Biotechnological Applications for a Common Class of Molecules" |
| Dec 10 | 11:00 am | Thomas M. Yankee, Pharm.D., Ph.D. University of Kansas Medical Center (hosted by Dr. Mark Fisher) |
"Gads-dependent signaling pathways and thymic selection" |
Spring 2010
| Date | Time | Speaker & Host | Title |
|---|---|---|---|
| Jan 22 | 11:00 am | David Davido, Ph.D. University of Kansas - Lawrence (hosted by Dr. Mark Fisher) |
"Determining sites on and domains in the HSV-1 immediate-early protein ICPO that affect virus-host interactions" |
| Jan 29 | 11:00 am | Yang Zhang, Ph.D. University of Michigan (hosted by Dr. Mark Fisher) |
"Progress and challenges in protein structure prediction" |
| Feb 5 | 11:00 am |
Jay Unruh, Ph.D. |
"Measurements of Molecular Interactions In Vivo Using Fluorescence Correlation Methods" |
| Feb 12 | 11:00 am |
Rathnam Chaguturu, Ph.D. |
canceled rescheduled on April 7 |
| Feb 19* | 11:00 am | Philip R. Hardwidge, Ph.D. University of Kansas Medical Center (hosted by Dr. Liskin Swint-Kruse) |
"Bacterial Effector Binding to Ribosomal Protein S3 Subverts NF-kappaB Function" |
| Feb 26 * | 11:00 am | Donald H. Burke University of Missouri - Columbia (hosted by Dr. Joseph Fontes) |
"Universtalist and specialists: Inhibition specificity of anti-HIV-1 aptamers |
| Mar 5 | 11:00 am |
Soumen Paul, Ph.D. |
"Histone Chaperone in Endothelial Gene Regulation" |
| Mar 19 | 11:00 am | Spring Break - No Seminar | |
| Mar 26 | 11:00 am | Stephen D. Levene Ph.D. University of Texas at Dallas (hosted by Dr. Kenneth Peterson) |
"Loop-mediated regulation by lac repressor: does DNA supercoiling play a role?" |
| Apr 2 | 11:00 am |
Aaron L. Lucius, Ph.D. |
"Mechanisms of Assembly and Polypeptide Translocation Catalyzed by the E.coli ClpA Molecular Motor " |
| Apr 7 * | 11:00 am Beller Conf Ctr |
Rathnam Chaguturu, Ph.D. |
"High Throughput Screening Laboratory at KU: One Stop Source for all Your Drug Discovery Needs" |
| Apr 9 | 11:00 am | Student Research Forum - No Seminar | |
| Apr 16 | 11:00 am | Wiliam Skach, M.D. Oregon Health & Science University (hosted by Dr. Alexey Ladokhin) |
"Cellular Mechanisms of Membrane Protein Folding" |
| Apr 23 | 11:00 am | Wonpil Im, Ph.D. University of Kansas - Lawrence (hosted by Dr. Alexey Ladokhin) |
"Mechanisms and Energetics of Protein/Peptide Interactions in Biological Membranes" |
| May 14 | 11:00 am |
Michael T. Henzl, Ph.D. |
"Impact of the Unliganded State on Parvalbumin Divalent Ion Affinity" |
| May 21 | 11:00 am | S. Walter Englander, Ph.D. University of Pennsylvania Medical School (hosted by Dr. Antonio Artigues) |
"How proteins do all of that as seen by hydrogen exchange. GroEL function. Protein folding. Lipoprotein structure." |
Fall 2009
| Date | Time | Speaker & Host | Title |
|---|---|---|---|
| Sept 4 | 11:00 am | Anne Hinderliter, Ph.D. University of Minnesota, Duluth (hosted by Dr. Aron Fenton) |
"Signaling at the Membrane: toward quantitative understanding" |
| Sept 11 | 11:00 am | Katsura Asano, Ph.D. Kansas State University (hosted by Dr. Joseph Fontes) |
"Translation factor control of stress signaling response: The case of Int6/elFe and rRNA mutations" |
| Sept 18 | 11:00 am | No Seminar - Faculty Retreat | |
| Sept 25 | 11:00 am | Joseph J. Falke, Ph.D. University of Colorado (hosted by Dr. Alexey Ladokhin) |
"Leukocyte chemotaxis: Molecular mechanisms of membrane targeting at the leading edge membrane" |
| Oct 2 | 11:00 am |
Karl Rozman, Ph.D. |
"Hormesis or the Effects of Low Doses of Toxic Agents" |
| Oct 9 | 11:00 am |
Florence Tama, Ph.D. |
"Coarse-grained modeling to characterize structure of biological molecules from low-resolution data" |
| Oct 23 | 11:00 am | Mohammad Ayoub Mir, Ph.D. University of Kansas Medical Center (hosted by Dr. Mark Fisher) |
"Hantavirus nucleocapsid protein guides transcript and translation initiation of viral mRNA" |
| Nov 6 | 11:00 am | Simon H. Friedman, Ph.D. University of Missouri, Kansas City (hosted by Dr. Mark Fisher) |
"Patterning of gene expression in cell monolayers using Light Activated RNA Interference (LARI)" |
| Nov 13 | 11:00 am | Matthew Goering, Graduate Student University of Kansas Medical Center |
"Cohesin and Chromosome Cohesion: Implications for DNA Double-Strand Break Repair" |
| Nov 20 | 11:00 am |
Eric Milot, Ph.D. |
"The combination of GAT-1 and Ikaros favors gene silencing in erythroid cells" |
| Nov 27 | 11:00 am | No Seminar - Thanksgiving Holiday | |
| Dec 11 | 11:00 am |
Aaron Gottschalk, Graduate Student |
"Modulation of Chromatin Structure by Snf2-like ATPases and Parp1" |
| Dec 18 | 11:00 am |
Edward B. Stephens, Ph.D. |
"The APOBEC3 Protein Family: An Innate Immune System Against Retroviruses" |
Spring 2009
| Date | Time | Location | Speaker & Host | Title |
|---|---|---|---|---|
| Jan 30 | 11:00 am | B018 SON | Todd Holyoak, Ph.D. University of Kansas Medical Center |
"Loops and Lids. The role of dynamics in PEPCK catalysis" |
| Feb 6 | 11:00 am | 1050 SON |
Liang Tang, Ph.D. |
"Virus meet Bacterium" |
| Feb 13 | 11:00 am | 1050 SON | David R. Setzer, Ph.D. University of Missouri - Columbia (hosted by Joesph Fontes) |
"Accidental Insights into the Mechanism of Transcription Activation" |
| Feb 20 | 11:00 am | 1050 SON | John Karanicolas, Ph.D. University of Kansas - Lawrence (hosted by Mark Fisher) |
"Designing Protein-Protein Interfaces" |
| Feb 27 | 11:00 am | 1050 SON | Stephen J. Brandt, M.D. Vanderbilt University Medical Center (hosted by Kenneth Peterson) |
"Emerging functions of LIM domain-binding and single-stranded DNA-binding proteins" |
| Mar 6 | 11:00 am | 1050 SON | Cynthia M. Dupureur, Ph.D. University of Missouri St. Lous (hosted by Aron Fenton) |
"Mechanistic and Biophysical Studies of Esterases" |
| Mar 13 | 11:00 am | B018 SON | Yuqi Wang, Ph.D. Saint Louis University (hosted by James Calvet) |
"Ubiquitination and G Protein Signaling in Yeast" |
| Mar 20 | 11:00 am | No Seminar - Spring Break | ||
| Mar 27 | 11:00 am | 1050 SON | Jim Bann, Ph.D. Wichita State University (hosted by Mark Fisher) |
"The nine rings: The role of histidine protonation in anthrax toxin pore formation" |
| Apr 3 | 11:00 am | 1050 SON |
Ben Weaver, Graduate Student |
"Regulatory Mechanisms of Slc39a4 (ZIP4) and Slc39a5 (ZIP5) " |
| Apr 10 | 11:00 am | No Seminar - Student Research Forum | ||
| Apr 17 | 11:00 am | 1050 SON | Angie Rizzino, Ph.D. University of Nebraska Medical Center (hosted by Joseph Fontes) |
"Sox transcription factors function as molecular rheostats to control the fate of pluripotenet stemcells" |
| Apr 24 | 11:00 am | 1023 OM |
P. Scott Hefty, Ph.D. |
"Developmental Gene Regulation in Chlamydia: Role and Mechanisms of an Atypical OmpR Response Regulator, ChxR" |
| May 1 | 11:00 am | B018 SON | Mitchell J. Weiss, MD, Ph.D. University of Pennsylvania (hosted by Kenneth Peterson) |
"Transcriptional Control of Erythro-Megakaryocytic Differentiation" |
| May 8 | 11:00 am | B018 SON | Dennis R. Livesay, Ph.D. University of North Carolina - Charlotte (hosted by Liskin Swint-Kruse) |
"Elucidating protein family sequence/structure/function relationships: from biophysics to empiricism and back" |
| May 15 | 11:00 am | B018 SON | Harvey F. Fisher, Ph.D. University of Kansas Medical Center |
"Experimental Application of the Second Rule of Transient-State Isotope Effects to the Phenylalanine Dehydrogenase Reaction" |
Fall 2008
| Date | Time | Speaker & Host | Title |
|---|---|---|---|
| Sep 5 | 11:00 am | David Thomas, Ph.D. University of Minnesota |
"Spectrocopic Probes of Muscle Protein Structural Dynamics" |
| Sep 12 | 11:00 am | Preston Hensley Pfizer Global Research & Development |
"Drug Discovery and the New Pharma-University Interface" |
| Sep 19 * | 11:00 am | Jeffrey L. Brodsky, Ph.D. University of Pittsburg, PA |
"Using Yeast to Defin the Molecular Basis of Protein Conformational Disease" |
| Sep 26 | 11:00 am | Suzanne Scarlata, Ph.D. Stony Brook University, New York |
"Cellular Regulation of Phospholipase C-beta Enzymes through G Proteins" |
| Oct 3 | 11:00 am |
Indranil Biswas, Ph.D. |
"Role of Two-component signal transduction systems in Streptococcus Mutans Virulence" |
| Oct 10 | 11:00 am |
Patricia L. Clark, Ph.D. |
"Co-translational Folding of an Aggregation-Prone Protein" |
| Oct 31 | 11:00 am | Jack F. Kirsch, Ph.D. University of California |
"Directed Evolution and Rational Design Approaches to Shifting Enzyme Paralog Function" |
| Nov 7 | No Seminar - Faculty Research Day | ||
| Nov 14 | 11:00 am | Paul Fitzpatrick, Ph.D. Texas A&M University |
"Catalytic and Regulatory Mechanisms of Tyrosine Hydroxylase" |
| Nov 21 | 11:00 am |
Philippe Prochasson, Ph.D. |
"Chromatin and transcriptional regulation by the HIR Complex and SWI/SNF chromatin remodeling" |
| Nov 28 | No Seminar - Thanksgiving Holiday | ||
| Dec 5 | 11:00 am | Duane C. Eichler, Ph.D. University of South Florida |
"Why a Urea Cycle Enzyme Regulates Vascular Endothelial Nitric Oxide Production" |
Spring 2008
| Date | Time | Speaker & Host | Title |
|---|---|---|---|
| Jan 4 | 11:00 am |
Lane K. Christienson, Ph.D. |
"MicroRNAs and Ovarian Function" |
| Jan 11 | 11:00 am | James Kranz, Ph.D. Johnson & Johnson PRD |
"Thrombin Conformational Diversity: Influence on Ligand Binding Energetics and Drug Discovery" |
| Jan 18 | 11:00 am | Luis A. Marky, Ph.D. University of Nebraska Medical Center |
"Sherlock Holmes's Adventures with Nucleic Acids" |
| Jan 25 | 11:00 am |
Julia Zeitlinger, Ph.D. |
"Transcriptional regulatory networks in the early Drosophilia embryo" |
| Feb 1 | 11:00 am | Bruno Hagenbuch, Ph.D. University of Kansas Medical Center |
"The multispecific organic anion transporters OATP1B1 and 1B3" |
| Feb 8 | 11:00 am | Steven Parnell, Ph.D. University of Kansas Medical Center |
"Signaling Pathways in Polysystic Kidney Disease" |
| Feb 15 | 11:00 am | Susan Egan, Ph.D. University of Kansas - Lawrence |
"AraC family Transcription Activators as Anti-bacterial Targets" |
| Feb 22 | 11:00 am | Mark Richter, Ph.D. University of Kansas - Lawrence |
"Generating Rotational Torque in the World's Tiniest Rotary Motor" |
| Feb 29 | 11:00 am | Xiaogang Li, Ph.D. Stowers Institute |
"Autosomal Dominant Polycystic Kidney Disease: Understanding the Mechanisms, Discovering Treatments" |
| Mar 7 | 11:00 am | Gerd Blobel, MD, Ph.D. Univ. of Pennsylvania School of Medicine |
"Navigating through chromatin: Regulation of hematopoietic development by transcription factor GATA-1" |
| Mar 14 | 11:00 am | Kyoungtae Kim, Ph.D. Missouri State University |
"Yeast Endoctosis: Roles of Actin Capping Protein and Dynamin-like Protein Vps1" |
| Mar 21 | 11:00 am | No Seminar - Spring Break | |
| Mar 28 | 11:00 am | Ben Weaver Graduate Student |
"The Genetics of Essential Metal Homeostasis during Development" |
| Apr 4 | 11:00 am | TBA | TBA |
| Apr 11 | 11:00 am | No Seminar - Student Research Forum | |
| Apr 18 | 11:00 am | Anne Kenworthy, Ph.D. Vanderbilt University |
"Structure and dynamics of membrane rafts" |
| Apr 25 | 11:00 am | John J. Tanner, Ph.D. University of Missouri - Columbia |
"Structural biology of proline catabolism" |
| May 2 | 11:00 am | Alexander Beeser, Ph.D. Kansas State University |
"Advancing selective in vivo Pak1 protein kinase inhibitors as translational therapeutics" |
Fall 2007
| Date | Time | Speaker & Host | Title |
|---|---|---|---|
| Sep 7 | 11:00 am | Russ Middaugh, Ph.D. University of Kansas - Lawrence |
The Polyanion World |
| Sep 14 | 11:00 am | Mark Wilson, Ph.D. University of Nebraska |
Hammer or Swiss-Army Knife?: Structural Conservation and Functional Diversity the DJ-1 Superfamily |
| Sep 21 | 11:00 am |
Barsanjit Mazumder, Ph.D. |
Translational Silencing in Monocytes: Role of Ribosomal Protein, Initiation Factors, and Signal to Resolve Inflammation |
| Sep 28 | 11:00 am | Jennifer Laurence, Ph.D. University of Kansas - LawrenceTBA |
Assessing the Structure-Activity Relationship of the Phosphatase of Regenerating Liver PRL-1 |
| Oct 5 | 11:00 am | Betty S. Pace, M.D. University of Texas - Dallas |
Genomic Approches to Elucidate Mechanisms for Fetal Globin Gene Regulation |
| Oct 12 | 11:00 am |
Tomasz Kordula, Ph.D. |
Tissue-specific gene regulation in astrocytes and glioma cell |
| Oct 19 | 11:00 am | Lee M. Graves, Ph.D. University of North Carolina - Chapel Hill |
Control of Pyrimidine Metabolism by Protein Kinases |
| Oct 26 | 11:00 am | Raymond Camahort Graduate Student |
Building centromeric chromatin: Studying how budding yeast find the needle in the haystack |
| Nov 2 | 11:00 am |
Russell Swerdlow, M.D. |
Mitochondria and Alzheimer's Disease |
| Nov 9 | 11:00 am | TBA | TBA |
| Nov 16 | 11:00 am | Eduardo Perozo, Ph.D. University of Chicago |
Structural basis of K+ channel activation and inactivation gating |
| Nov 23 | 11:00 am | No Seminar - Thanksgiving Holiday | |
| Nov 30 | 11:00 am | Lisa Timmons, Ph.D. University of Kansas - Lawrence |
ABC transporters are required for efficient RNAi in Caenorhabditis elegans |
| Dec 7 | 11:00 am | Brian M. Baker University of Notre Dame |
T cell receptor recognition of antigen: more questions than answers? |
| Dec 14 | 11:00 am |
Ali Shilatifard, Ph.D. |
Chromatin Modifications by Methylation and Human Leukemia |
Spring 2007
| Date | Time | Speaker & Host | Title |
|---|---|---|---|
| Jan 5 | 11:00 am | Chen-Yong Lin, Ph.D. Gerogetown Medical Center |
"Deregulation of matriptase in human carcinomas" |
| Jan 12 | 11:00 am | Rong Li, Ph.D. Stowers Institute of Research |
"In-vivo biochemical analysis of dynamic protein interactions in the MAP kinase signaling cascade" |
| Jan 19 | 11:00 am |
Brian V. Geisbrecht, Ph.D. |
"Using Structure to Unravel the Mechanism of Staphylococcal Complement Inhibitors" |
| Jan 26 | 11:00 am |
Arthur Cooper, Ph.D. |
"Role of Transglutaminases in Neurodegeneraive Diseases" |
| Feb 2 | 11:00 am | Maria Schumacher, Ph.D. Univ of Texas M.D. Anderson Cancer Ctr |
"Peptide Self-Assembly and Pore Formation in Membranes: The Use of Combinatorial Chemistry as a Learning Tool" |
| Feb 9 | 11:00 am | William C. WImley, Ph.D. Tulane University Health Services Center |
"Peptide Self-Assembly and Pore Formation in Membranes: The Use of Combinatorial Chemistry as a Learning Tool" |
| Feb 16 | 11:00 am | Yoshi Azuma, Ph.D. University of Kansas - Lawrence |
"Role of SUMO modification in vertebrate mitosis" |
| Feb 23 | 11:00 am | Jorg Bungert, Ph.D. University of Florida |
"Locus Control Region Mediated Recruitment of Transcription Complexes to the Beta-Globin Gene Locus" |
| Mar 2 | 11:00 am |
D. Wayne Bolen, Ph.D. |
"Nature's emphasis on the peptide backbone in osmolyte-induced protein folding/unfolding" |
| Mar 9 | 11:00 am | Mark S. Hargrove, Ph.D. Iowa State University |
"Structural highlights in the evolution of oxygen transport in plants" |
| Mar 16 | 11:00 am | Dagmar Ringe, Ph.D. Brandeis University |
"Iron mediated control of virulence: the diptheria tox repressor" |
| Mar 23 | 11:00 am | No Seminar - Spring Break | |
| Mar 30 | 11:00 am | Tom Roche, Ph.D. Kansas State University |
"Regulation of pyruvate dehydrogenase kinase (PDK) and restriction of PDK activity in treating diabetes, heart disease, and cancer" |
| Apr 6 | 11:00 am | No Seminar | |
| Apr 13 | 11:00 am |
Stuart Smith, Ph.D., D.Sc. co-sponsored with Dept. of Medicine |
"Structural & functional analysis of the fatty acid biosynthetic enzymes in mammalian mitochondria: Coupling of lipogenic and lipoylation pathways" |
| Apr 20 | 11:00 am | David L. Brautigan, Ph.D., University of Virginia School of Medicine |
"Opposition to Cytokine Signaling by Novel Protein Phosphatases" |
|
****SPECIAL |
SEMINAR**** |
|
"Regulation of the Shp2 Protein Tyrosine Phosphatse in cell Signaling and Oncogenesis" |
| Apr 27 | 11:00 am |
Henrik Dohlman, Ph.D. |
"G protein signaling at the endosome" |
| May 4 | 11:00 am |
Andrei B. Belousov, Ph.D. |
"Glutamate-dependent neuronal plasticity in the CNS: chemical and electrical synapses" |
Fall 2006
| Date | Time | Speaker & Host | Title |
|---|---|---|---|
| Sep 8 | 11:00 am | Wolfram R. Zuckert, Ph.D. University of Kansas Medical Center |
"Rules and Regulators of Lipoprotein Secretion in Borrelia Spirochetes" |
| Sep 15 | 11:00 am | C. Nick Pace, Ph.D. Texas A&M University Health Science Ctr |
"Fine Tuning Protein Stability and the pK Values of Ionizable Groups " |
| Sep 22 | 11:00 am | Richard N. Armstrong, Ph.D. Vanderbilt University |
"Structural and Functional Genomics of Antibiotic Resistance" |
| Sep 29 | 11:00 am | Canceled | |
| Oct 6 | 11:00 am |
Brian S. J. Blagg, Ph.D. |
"Managing the Hsp90 Protein Folding Process with Small Molecules" |
| Oct 13 | 11:00 am | Curt Hagedorn, M.D. University of Kansas Medical Center |
"Role of an RNA Binding Protein in Epithelial Cancer Progression" |
| Oct 20 | 11:00 am | Joesph Lutkenhaus, Ph.D. University of Kansas Medical Center |
"Regulating Bacterial Cell Division" |
| Oct 27 | 11:00 am | Marco Blanchette, Ph.D. University of California - Berkeley |
"Functional Genomic Analysis of Drosophilia Alternative Splicing Factors" |
| Nov 3 | 11:00 am | Peter Rowe, Ph.D. University of Kansas Medical Center |
"Mineralization and bone-renal pathways: the harmonious struggle of the living skeleton" |
| Nov 10 | 11:00 am | Michael Petris, Ph.D. University of Missouri - Columbia |
"Inflammation is a novel regulator of copper homeostasis" |
| Nov 17 | 11:00 am | Stuart Smith, Ph.D., DSC Children's Hospital Oakland Rsrch Inst co-sponsored with Dept of Medicine |
"Structural & functional analysis of the fatty acid biosynthetic enzymes in mammalian mitochondria: Coupling of lipogenic &lipoylation pathways" |
| Nov 24 | 11:00 am | No Seminar - Thanksgiving Holiday | |
| Dec 1 | 11:00 am | Canceled due to Inclement Weather |
|
| Dec 8 | 11:00 am | No Seminar - Department Event | |
| Dec 15 | 11:00 am |
Robert Fuller, Ph.D. |
"Specificity and inhibition of eukaryotic proprotein processing proteases" |
Spring 2006
| Date | Time | Speaker & Host | Title |
|---|---|---|---|
| Jan 13 | 11:00 am | Gregory Petsko, Ph.D. Brandeis University |
On the Origin of Enzymatic Species: How New Enzymes Evolve from Old Ones |
| Jan 20 | 11:00 am | R. John Collier, Ph.D. Harvard Medical School |
Anthrax Toxin: Mechanism of Membrane Translocation |
| Jan 27 | 11:00 am | Jay Vivian, Ph.D. University of Kansas Medical Center |
Genetic Screens in Mouse Embryonic Stem Cells |
| Feb 3 | 11:00 am | Paul E. Smith, Ph.D. Kansas State University |
Computer Simulation of the Delta Opioid Receptor and Delta Opioid Receptor Selective Peptide Agonists |
| Feb 10 | 11:00 am | Canceled | |
| Feb 17 | 11:00 am | Page Geiger, Ph.D. University of Kansas Medical Center |
Exercise Training in the Prevention of Insulin Resistance and Type 2 Diabetes: A Cellular Approach |
| Feb 24 | 11:00 am | Vincent J. Hilser, Ph.D. University of Texas Medical Branch |
What's in a Protein Ensemble |
| Mar 3 | 11:00 am | Dorothy Beckett, Ph.D. University of Maryland |
Regulating the Regulators; Control of Transcription Repression Complex |
| Mar 10 | 11:00 am | A. L. Burlingame, Ph.D. University of California San Francisco |
The Challenge of Defining Protein Postranslational Complexity Using Mass Spectrometry |
| Mar 17 | 11:00 am | John M. Tomich, Ph.D. Kansas State University |
"Redesigning Nature: Studies on New Channel-Forming Sequences Derived from the Second Transmembrane Segment of the Glycine Receptor-Subunit" |
| Mar 24 | 11:00 am | No Seminar - Spring Break | |
| Mar 31 | 11:00 am | Hao Zhu, Ph.D. University of Kansas Medical Center |
"NCB5OR, Oxidative Stress and Diabetes" |
| Apr 7 | 11:00 am | Roberto De Guzman, Ph.D. University of Kansas - Lawrence |
"NMR Studies of Proteins Involved in Bacterial and Viral Pathogenesis" |
| Apr 14 Lied Aud. |
11:00 am | C. Robert Matthews, Ph.D. University of Massachusetts Medical School Note change of location to Lied Auditorium |
"Are protein folding mechanisms better conserved than their amino acid sequences? The roles of topology and sequence in controlling the folding mechanisms of TIM barrel proteins" |
| Apr 21 | 11:00 am | Joyce A. Lloyd, Ph.D. Virginia Commonwealth University |
"Globin Gene Regulation: Bottom-Up and Top-Down Approaches" |
| Apr 28 | 11:00 am | Malin M. Young, Ph.D. Sandia National Laboratories |
"Protein Structural characterization using chemical cross-linking, mass spectrometry and modeling" |
| May 5 | 11:00 am | Canceled | |
| May 12 | 11:00 am | Jackob Moskovitz, D.Sc. University of Kansas - Lawrence |
"The methionine sulfoxide reductase system and its role in antioxidant defense and survival" |
| May 19 | 11:00 am | Andrew D. Robertson, Ph.D. University of Iowa |
"Structural Consequences of Insertions Among Ubiquitin-Like Proteins |
Fall 2005
| Date | Time | Speaker & Host | Title |
|---|---|---|---|
| Sept 9 | 11:00 am | Jinxi Wang, M.D., Ph.D. Orthopedics, University of Kansas Medical Center |
Enhancement of Skeletal Repair by Biochemical & Molecular Means |
| Sept 16 | 11:00 am | Henry Miziorko, Ph.D. University of Missouri - Kansas City |
HMG-CoA Synthase: Functional Correlations and a Reversal of Expectations |
| Sept 23 | 11:00 am | Michael Washburn, Ph.D. Stowers Institute, Kansas City |
Quantitative Proteomic Analysis via MudPIT |
| Sept 30 | 11:00 am | Li Wang, Ph.D. University of Kansas Medical Center |
'Orphan' but not lonely: how much can nuclear receptor SHP do? |
| Oct 7 | 11:00 am | No Seminar - SOM Faculty Retreat | |
| Oct 14 | 11:00 am | John Laity, Ph.D. University of Missouri-Kansas City |
Are we full of Zinc? Binding and structural studies of metalloregulatory domains from MTF-1 and Zap1 |
| Oct 21 | 11:00 am | George Reed, Ph.D. University of Wisconsin |
Encolase. A Jewel in the Crown of Glycolysis |
| Oct 28 | 11:00 am | T. Chris Gamblin, Ph.D. University of Kansas - Lawrence |
Modeling Neurodegenerative Tauopathies In Vitro |
| Nov 4 | 11:00 am | David Toft, Ph.D. Mayo Clinic |
Chaperoning Cell Regulatory Proteins through Hsp90 |
| Nov 11 | 11:00 am | Yeon-Kyun Shin, Ph.D. Iowa State University |
Intermediates in SNARE-Mediated Membrane Fusion |
| Nov 18 | 11:00 am | Madeline A. Shea, Ph.D. University of Iowas |
Calmodulin Regulation: A Tale of Two Domains |
| Nov 25 | 11:00 am | No Seminar - Holiday | |
| Dec 2 | 11:00 am | Joseph Fontes, Ph.D. Faculty Candidate |
The ZXD family: Novel regulators of MHC II transcription |
| Dec 5 | 8:30 - 10:00 a.m. | Jeremy Sanford, Ph.D. Faculty Candidate note new location: Lied Auditorium |
Getting the message: RNA binding proteins and post-transcriptional gene expression |
| Dec 6 | 9:00 am | Steve Patrick, Ph.D. Faculty Candidate note new location: 1014 Orr Major |
Biochemical Processing of Cisplatin-DNA Interstrand Cross-links (ICLs) |
| Dec 9 | 11:00 am | Felix Koberling PicoQuant, Berlin, Germany Special Seminar |
Time-resolved Confocal Fluorescence Microscopy: Novel Technical Features and Applications for FLIM, FRET and FCS" |
| Dec 16 | 11:00 am | Scott Warder, Ph.D. Abbott Labs |
Discovery of Protein Markers for Pharmaceutical Drug Development |
Spring 2005
| Date | Time | Speaker & Host | Title |
|---|---|---|---|
| Jan 14 | 11:00 am | Jonathan Silberg, Ph.D. Rice University |
"On the conservative nature of protein recombination" |
| Jan 21 | 11:00 am | Sue Jaspersen, Ph.D. University of Colorado, Boulder |
"Yeast Centrosomes: Structure, Duplication and Function" |
| Jan 28 | 11:00 am | Chris Lorson, Ph.D. University of Missouri - Coloumbia |
"The Role of Survival Motor Neuron (SMN) in the Development of Spinal Muscular Atrophy" |
| Feb 4 | 11:00 am | Michal Zolkiewski, Ph.D. Kansas State University |
"Structure and Function of ClpB: a Protein-Disaggregating Molecular Chaperone" |
| Feb 11 | 11:00 am | Emily Scott, Ph.D. University of Kansas-Lawrence |
"Structure and Function of Cytochrome P450s involved in Xenobiotic Metabolism" |
| Feb 18 | 11:00 am | Xiao-Qiang (Sean) Yu, Ph.D. University of Missouri - Kansas City |
"Lectins in innate immune responses of an insect" |
| Feb 25 | 11:00 am | Deborah S. Wuttke, Ph.D. University of Colorado |
"Tying up the Ends: Recognition of Single-Stranded DNA at Telomeres" |
| Mar 11 | 11:00 am | Mario Ernesto Rivera-Laos, Ph.D. University of Kansas - Lawrence |
"Heme Oxygenase in Pathogenic Bacteria: Insights from Magnetic Resonance Investigations of the Active Site" |
| Mar 18 | 11:00 am | Yu-Jui Yvonne Wan, Ph.D. Dept of Pharmacology, Toxicology & Therapeutics, KUMC |
"Functional Analysis of Retionoid X receptor alpha in Hepatocyte" |
| Apr 1 | 11:00 am | Don G. Ennis, Ph.D. University of Louisiana - Lafayette |
"Development of a Mutagenesis Assay in Transgenic Animals: Investigations of Chronic Infections and Carcinogenesis" |
| Apr 8 | 11:00 am | Frederick Sachs, Ph.D. Hughes Center for Single Molecule Biophysics |
"Mechanosensitive ion channels: from bench to bedside" |
| Apr 15 | 11:00 am | Richard Honzatko, Ph.D. Iowa State University |
"Ligand Cooperativity in Fructose-1,6-bishoshpatase" |
| Apr 22 | 11:00 am | Philip J. Thomas, Ph.D. UT Southwester Medical Center at Dallas |
"Cystic Fibrosis: Disease of Altered Protein Folding" |
| Apr 29 | 11:00 am | Thomas Nowak, Ph.D. University of Notre Dame |
"Fundamental Steps in Pyruvate Kinase: Phosphoryl Transfer and Enolpyruvate Protonation" |
| May 6 | 11:00 am | Patrick Loria, Ph.D. Yale University |
"Conversation and Control of Enzyme Dynamics for Optimal Catalysis" |
| May 13 | 11:00 am | Jill Trewhella, Ph.D. Dept of Chemistry, University of Utah, |
Structural Themes and Variations in Kinase Activation and Targeting |
Fall 2004
| Date | Time | Speaker & Host | Title |
|---|---|---|---|
| Sept 10 | 11:00 am | Liskin Swint-Kruse, PhD. Dept of Biochemistry & Molecular Biology, KUMC |
"Tools to identify functionally relevant fine details in protein structure" |
| Sept 24 | 10:00 am
Lied Aud. |
Carey Johnson, PhD Dept of Chemistry University of Kansas - Lawrence |
"Single-Molecule Spectroscopy of Calcium Signaling: Dynamics and Target Interactions of Calmodulin" |
| Oct 8 | 11:00 am | David Mount, Ph.D. University of Arizona |
"Cancer Bioinformatics: support for the discovery of new drugs and diagnostic tools" |
| Oct 15 | 11:00 am | Rolf Jakobi, Ph.D. Kansas City University of Medicine and Biosciences |
"The Role of p21-Activated Protein Kinase2 in Cell Survival and Cell Death" |
| Oct 22 | 11:00 am | Karen G. Fleming, Ph.D. Johns Hopkins University |
"Membrane Protein Interactions: Thermodynamics in the Role of Sequence Motifs" |
| Oct 29 | 11:00 am | Edith Chang, Ph.D. Kansas City University of Medicine and Biosciences |
"The Role of cyclooxygenase 2 in Cell Survival, Cell Motility and Colon Cancer Development" |
| Nov 5 | 11:00 am | Anthony L. Fink, Ph.D. University of California, Santa Cruz |
"The molecular basis for ß-synuclein fibrillation: Implications for Parkinson's Disease" |
| Nov 12 | 11:00 am | Greg Reinhart, Ph.D. Texas A&M |
"Using Fluctuation Spectroscopy to Study Protein-Protein Interactions" |
| Nov 19 | 11:00 am | Art Johnson, Ph.D Texas A&M |
"Maintenance of Membrane Integrity by Ribosomes, BiP, and Translocons during ER Protein Trafficking" |
| Nov 26 | 11:00 am | No Seminar Thanksgiving Holiday |
|
| Dec 3 | 11:00 am | John Robertson, Ph.D. Dept of Pharmacology & Toxicology, KUMC |
"Caspase-2-mediated engagement of the mitochondrial apoptotic pathway" |
| Dec 10 | 11:00 am | Sarah Bondos, Ph.D. Rice University |
"Integrating Information: Hox Proteins physically and genetically interact with proteins from an array of cellular systems" |
| Dec 17 | 11:00 am | Audrey Lambs, Ph.D. University of Kansas-Lawrence |
"Siderophore Biosynthesis by Pseudomonas aeruginosa" |