Department Research Interests
Learn about the diverse research focus areas of the faculty in the Department of Biochemistry and Molecular Biology.
Regulation of gene transcription. Gap junctional coupling in neuronal survival and death.
Genome maintenance. Elucidating how DNA damage is generated, processed and repaired using structural and biochemical approaches.
Role of hormones in breast cancer, crosstalk between inflammation and steroid receptor action.
Membrane proteins in apoptotic regulation and cancer targeting, Bcl-2 proteins, bacterial toxins, antimicrobial peptides, biophysical techniques.
Human β-globin gene regulation using transgenic mice and cell lines generated with β- globin locus yeast artificial chromosomes.
Protein degradation in the cell. Biochemical and cell biological analyses of assembly and localization of proteasomes and their autophagic degradation.
The role of post-translational modification in cell cycle progression and development; glycobiology; signal transduction.
Applications of protein evolution to personalized medicine and protein engineering; transcriptional regulation of bacterial metabolism.
Structural basis of sensory perception. Applying X-ray crystallography and cryo-EM to investigate how ion channels are activated by sensory inputs.