Funding Source: NIH HEAL Initiative - NIAMS

KUMC PI: Dr. Andrea Chadwick

KUMC Co-Investigators: Dr. Lora Black, Dr. Neena Sharma and Dr. Dylan Bassett

KUMC Study Number: 148103

Purpose: The NIH is seeking an improved understanding of the mechanisms underlying chronic back pain and to identify treatments that are most effective in participants.

Candidates: Participants who have had persistent low back pain for 3 months or longer

Funding Source: KUMC Research Institute Pilot Award

Principal Investigators: Dr. Andrea Chadwick and Dr. Douglas Wright

Co-Investigators: Dr. Erin Young, Dr. Mamatha Pasnoor

KUMC Study Number: 144620

Purpose: We hope to learn more about the long-term effects of opioid use as it pertains to nerve density sizes and heightened pain sensitivity.

Candidates:

Healthy volunteers -OR-

Chronic pain participants who have been using opioid medications for 3 months or longer -OR-

Chronic pain participants who do not use opioid medications

Funding Source: NIH

Principal Investigator: Dr. Douglas Wright

Co-Investigator: Dr. Andrea Chadwick

Purpose: The goal of this study is to broaden our understanding of the role of methylgyoxal (MGO) in chronic pain by comparing MGO levels in participants with different pain conditions.

Candidates:

Healthy Volunteers -OR-

Participants who have chronic low back pain due to a disc aberrancy -OR-

Participants with Type II Diabetes and painful neuropathy

Funding Source: KUMC Frontiers Pilot Grant

Principal Investigator: Dr. Paige Geiger

Co-Investigator: Dr. Andrea Chadwick, Dr. Mamatha Pasnoor, Dr. Douglas Wright

KUMC Study Number: 143811

Purpose: This project will study the effects of heat treatment (sitting in a hot tub) on blood glucose levels and pain transmissions in skin nerves that may help treat conditions like Type 2 Diabetes.

Candidates: Pre-diabetic participants with neuropathy

Funding Source: NIH K23 Mentored Patient-Oriented Research Career Development Award

Principal Investigator: Dr. Andrea Chadwick

Co-Investigators: Dr. William Brooks, Dr. Joshua Bunch, Dr. Douglas Burton, Dr. Brandon Carlson, Dr. Justin Davis, Dr. Robert Jackson, Dr. Laura Martin and Dr. Neena Sharma

KUMC Study Number: 140263

Purpose: Researchers hope to learn whether certain risk factors and patient characteristics are linked with, and possibly can predict, the development of chronic pain after lumbar spine surgery.

Candidates:

Healthy volunteers -OR-

Participants undergoing their first lumbar spine surgery -OR-

Participants who have been diagnosed with FBSS

Principal Investigator: Dr. Andrea Chadwick

Co-Investigators: Dr. Edward Braun, Dr. Talal Khan, Dr. Usman Latif, Dr. Andrew Sack, Dr. Dawood Sayed, Dr. Timothy Sowder

KUMC Study Number: 142378

Purpose: By doing this study, researchers hope to learn whether certain patient characteristics are linked with, and possibly can predict, the response to pain procedures.

Findings: Coming soon

Funding Source: KUMC Frontiers Trailblazer Award

Principal Investigator: Dr. Rebecca Lepping

Co-Investigator: Dr. Andrea Chadwick

KUMC Study Number: 144158

Purpose: By doing this study, researchers hope to learn more about how listening to music or nature sounds affect a person with Fibromyalgia’s sensitivity to pain.

Findings: Coming soon

Funding Source: Frontiers Clinical Pilot Award

Principal Investigators: Dr. Andrea Chadwick and Dr. Paige Geiger

KUMC Study Number: 142795

Purpose: By doing this study, researchers hope to learn more about how heat therapy affects pain severity and quality of life in patients with chronic pain due to fibromyalgia.

Findings: Coming soon