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Ryan Townley, MD

Ryan Townley portrait
Assistant Professor, Neurology

Fellowship Program Director, Fellowship Program Director, SOM-Kansas City, Neurology

Medical Director, Memory Clinic, Medical Director, Memory Clinic, TUKHS - The University of Kansas Health Systems

Professional Background

Ryan Townley, M.D., is an assistant professor in the Department of Neurology at the University of Kansas Medical Center and is the director of the Cognitive and Behavioral Neurology Fellowship. He is also the Alzheimer's Clinical Trials Consortium Co-Principal Investigator and a Principal Investigator of many clinical research studies at the University of Kansas Alzheimer's Disease Research Center.

Dr. Townley is certified by the American Board of Psychiatry and Neurology and is UCNS-certified in Behavioral Neurology and Neuropsychiatry. Before joining the KU Medical Center faculty in August 2019, he completed a two-year cognitive-behavioral fellowship at the Mayo Clinic School of Graduate Medical Education, where he also finished his neurology residency. He graduated from the University of Kansas School of Medicine, where he earned the 2013 Dewey K. Ziegler Award for Excellence in Neurology presented by the KU Department of Neurology and was honored with the American Academy of Neurology's Outstanding Neurology Medical Student Award. Prior to medical school, he earned a bachelor of science in neurobiology from the University of Kansas.

Education and Training
  • BS, Neurobiology, University of Kansas, Lawrence, KS
  • MD, Medical Doctor, University of Kansas School of Medicine, Kansas City, KS
  • Other, Neurology, Mayo School of Graduate Medical Education, Rochester, MN
  • Other, Cognitive and Behavioral Neurology, Mayo School of Graduate Medical Education, Rochester, MN
Licensure, Accreditations & Certifications
  • ABPN Certified in Psychiatry and Neurology, American Board of Psychiatry and Neurology
  • Medical License, Kansas State Board of Healing Arts
  • UCNS Certified in Behavioral Neurology and Neuropsychiatry , United Council for Neurologic Subspecialties
Professional Affiliations
  • Lewy Body Disease Association, Clinical Education Task Force , Member, 2023 - Present
  • International Society to Advance Alzheimer's Research and Treatment, Member, 2017 - Present
  • American Academy of Neurology, Member, 2015 - Present



In addition to authoring a growing number of publications, Dr. Townley has presented numerous lectures and posters nationally and around the world. His clinical and research interests include Alzheimer's diseases variants such as posterior cortical atrophy and dysexecutive Alzheimer's, dementia with Lewy bodies, normal pressure hydrocephalus, and frontotemporal lobar degeneration. He also has professional interests in patient education and neurological disease-related seminars, resident and medical student education, and preventative health against neurodegenerative disease.

Current Research and Grants
  • AHEAD 3-45 Study, National Institute on Aging (NIA), PI
  • Study to Evaluate the Safety, Tolerability and Efficacy of CT1812 in Subjects With Mild to Moderate Dementia With Lewy Bodies (COG1201), National Institute on Aging , Co-PI
  • Alzheimer’s Plasma Extension (APEX) Study, NIH/NIA, Site-PI
  • Townley, R., A, Graff-Radford, J, Mantyh, W., G, Botha, H, Polsinelli, A., J, Przybelski, S., A, Machulda, M., M, Makhlouf, A., T, Senjem, M., L, Murray, M., E, Reichard, R., R, Savica, R, Boeve, B., F, Drubach, D., A, Josephs, K., A, Knopman, D., S, Lowe, V., J, Jack, Jr, C., R, Petersen, R., C, Jones, D., T. 2020. Progressive dysexecutive syndrome due to Alzheimer's disease: a description of 55 cases and comparison to other phenotypes.. Brain communications, 2 (1), fcaa068
  • Townley, R., A, Botha, H, Graff-Radford, J, Whitwell, J, Boeve, B., F, Machulda, M., M, Fields, J., A, Drubach, D., A, Savica, R, Petersen, R., C, Senjem, M., L, Knopman, D., S, Lowe, V., J, Jack, Jr, C., R, Josephs, K., A, Jones, D., T. 2021. Posterior cortical atrophy phenotypic heterogeneity revealed by decoding (18)F-FDG-PET.. Brain communications, 3 (4), fcab182
  • Pleen, Joseph, Townley, Ryan. 2021. Alzheimer’s disease clinical trial update 2019–2021
  • Townley, R., A, Syrjanen, J., A, Botha, H, Kremers, W., K, Aakre, J., A, Fields, J., A, Machulda, M., M, Graff-Radford, J, Savica, R, Jones, D., T, Knopman, D., S, Petersen, R., C, Boeve, B., F. 2019. Comparison of the Short Test of Mental Status and the Montreal Cognitive Assessment Across the Cognitive Spectrum.. Mayo Clinic proceedings, 94 (8), 1516-1523
  • Townley, R., A, Botha, H, Graff-Radford, J, Boeve, B., F, Petersen, R., C, Senjem, M., L, Knopman, D., S, Lowe, V, Jack, Jr, C., R, Jones, D., T. 2018. (18)F-FDG PET-CT pattern in idiopathic normal pressure hydrocephalus.. NeuroImage. Clinical, 18, 897-902
  • Townley, R., A, Boeve, B., F, Benarroch, E., E. 2018. Progranulin: Functions and neurologic correlations.. Neurology, 90 (3), 118-125
  • Doher, N, Davoudi, V, Magaki, S, Townley, R., A, Haeri, M, Vinters, H., V. 2023. Illustrated Neuropathologic Diagnosis of Alzheimer's Disease.. Neurology international, 15 (3), 857-867
  • Vidoni, E., D, Morris, J., K, Watts, A, Perry, M, Clutton, J, Van Sciver, A, Kamat, A., S, Mahnken, J, Hunt, S., L, Townley, R, Honea, R, Shaw, A., R, Johnson, D., K, Vacek, J, Burns, J., M. 2021. Effect of aerobic exercise on amyloid accumulation in preclinical Alzheimer's: A 1-year randomized controlled trial.. PloS one, 16 (1), e0244893
  • 2022. Chapter 78 - Frontotemporal Dementias
  • Perales-Puchalt, J, Townley, R, Niedens, M, Vidoni, E., D, Greiner, K., A, Zufer, T, Schwasinger-Schmidt, T, McGee, J., L, Arreaza, H, Burns, J., M. 2022. Acceptability and Preliminary Effectiveness of a Remote Dementia Educational Training Among Primary Care Providers and Health Navigators.. Journal of Alzheimer's disease : JAD, 89 (4), 1375-1384