Overview of Core

Core Director:
Alan Yu, M.B., B.Chir.
E-mail: ayu@kumc.edu
Tel. 913.588.9252

For Patients:
· Active PKD Trials
· Volunteer for the PKD Research Participant Registry

PKD is a "therapy-ripe" disease and the number of potential targets for drug therapy increases at a phenomenal rate. Academic investigators can play a major role in translational research by critically evaluating potential targets and drugs and bringing promising candidates to early phase clinical trials. Thus, the goal of this core is to develop a formal infrastructure to support continued growth in PKD clinical trial activity, to develop innovative tools to facilitate clinical research (including trial recruitment, biomarker monitoring, and outcomes research), to facilitate investigator-initiated trials and to provide a pathway for investigators to expedite the translation of novel or repurposed drug candidates to clinical trials. This will be achieved through the provision of consultative advice on drug development, a patient registry network for clinical trials recruitment, resources and services for conducting clinical trials, and a searchable integrated clinical data repository for observational research.