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cryo-Electron Microscopy

Beginning in May 2023, the University of Kansas Medical Center will be home to a Thermo Glacios cryo-EM with Selectris and Falcon 4.

Cryo Transmission Electron Microscope

The new state-of-the-art Thermo Glacios cryo-electron microscope with Selectris and Falcon 4 was acquired through a partnership between the Executive Vice Chancellor, the KU Cancer Center and the KU School of Medicine.

About Cryo-Electron Microscopy

Cryo-electron microscopy can image macromolecular complexes at the atom level. Recent breakthroughs in this technology have spawned a scientific revolution, revealing molecular details of important biological macromolecules. This technique can be particularly helpful for visualizing the structures of integral membrane proteins, large complexes with many subunits and macromolecules that are highly dynamic. Using the new Glacios at KU Medical Center, researchers will be able to carry out the critical first steps of obtaining such structures. Learn more about cryo-electron microscopy in Nature.

Information about cryo-EM core services at KU Medical Center will be shared when it is available.

Seminar Series

We invite members of the KU Medical Center community and our research partners to join us for our upcoming seminar series about this new technology. The events feature renowned speakers from the international research community.

In May 2023, the medical center will host a keynote speaker and equipment unveiling event. Details will be shared when they are available. 

Past Seminars

Feb 24, 2023

Dr. Gabriel Lander, Scripps Research Institute
Do we still need crystallography? A case study in targeted protein degradation

(requires login)

"cryo-EM Initiatives"; Dr. Peter Smith

"cryo-EM Technology Introduction"; Dr. Brad Pesavato

Pilot Projects

Congratulations to the recipients of pilot project awards sponsored by the KU School of Medicine.


Project Title

Jeffrey L Bose, P.hD.

Structural studies of S. aureus fatty acid kinase

X. Long Zheng, M.D., P.h.D.

Autoantibody-induced conformational change of ADAMTS13

Maria Kalamvoki, P.hD.

Subjugation of endosomal, autophagy and exocytosis pathways by HSV-1 ICP0

Jeroen Roelofs, P.h.D

Structure-function analysis of assembly intermediates of the proteasome

Electron Microscopy Research Laboratory

University of Kansas Medical Center
B015 Lied Biomedical Research Building
3901 Rainbow Blvd.
Kansas City, KS 66160