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Liang Zheng, Ph.D.

Liang Zheng portrait
Research Assistant Professor, Pathology and Laboratory Medicine
lzheng@kumc.edu

Professional Background

Dr. Zheng is a member of the Zheng Laboratory. He earned his PhD, Marine Life Science, from Hokkaido University, Japan. Dr. Zheng joined the University of Kansas Medical Center, Department of Pathology and Laboratory Medicine as Research Assistant Professor in July 2020.

Education and Training
  • BSc, Biology , Central South University of Forestry and Technology, China
  • MSC, Marine Biology , Shanghai Ocean University
  • PhD, Marine Life Science , Hokkaido University
  • Post Doctoral Fellowship, Toxicology, University of Illinois at Chicago
  • Post Doctoral Fellowship, Pathology , University of Alabama at Birmingham

Research

Overview

My research interests involve elucidation of the disease mechanism of Thrombotic Microangiopathy (TMA), a group of rare yet life-threatening thrombotic disorders, and development of new therapeutics in the animal models of TMA. Using the zebrafish and mouse models, my current work focuses on the identification and characterization of genetic factors that modulate the pathogenesis of TMA, and elucidation of the role of environmental factors that may act as disease modifiers.

Publications
  • Zheng, L, Abdelgawwad, M., S, Zhang, D, Xu, L, Wei, S, Cao, W, Zheng, X., L. 2020. Histone-induced thrombotic thrombocytopenic purpura in adamts13-/- zebrafish depends on von Willebrand factor.. Haematologica, 105 (4), 1107-1119
  • Basu, Malay., Kumar, Massicano, Felipe, Yu, Lijia, Halkidis, Konstantine, Pillai, Vikram, Cao, Wenjing, Zheng, Liang, Zheng, X.., Long. 2020. Exome Sequencing Identifies Abnormalities in Glycosylation and ANKRD36C in Patients with Immune-Mediated Thrombotic Thrombocytopenic Purpura. THROMBOSIS AND HAEMOSTASIS
  • Zheng, L, Zhang, D, Cao, W, Song, W., C, Zheng, X., L. 2019. Synergistic effects of ADAMTS13 deficiency and complement activation in pathogenesis of thrombotic microangiopathy.. Blood, 134 (13), 1095-1105
  • Abdelgawwad, M., S, Cao, W, Zheng, L, Kocher, N., K, Williams, L., A, Zheng, X., L. 2018. Transfusion of Platelets Loaded With Recombinant ADAMTS13 (A Disintegrin and Metalloprotease With Thrombospondin Type 1 Repeats-13) Is Efficacious for Inhibiting Arterial Thrombosis Associated With Thrombotic Thrombocytopenic Purpura.. Arteriosclerosis, thrombosis, and vascular biology, 38 (11), 2731-2743