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Lauren E. Nye, MD

Lauren  Nye portrait
Breast Cancer Prevention Program Services, Care Connection Partnership; Medical Directorship for Breast Cancer Prevention Clinical Services for the KU Cancer Center, Medical Directorship for Breast Cancer Prevention Clinical Services for the KU Cancer Center
lnye@kumc.edu

Professional Background

Dr. Lauren Nye is certified by the American Board of Internal Medicine with a subcertification in medical oncology. She completed a fellowship at Northwestern Memorial Hospital. She earned her medical degree from the University of Kansas School of Medicine and completed her residency at Northwestern Memorial Hospital. Dr. Nye specializes in the management of the continuum of breast cancer - from breast cancer prevention to treatment of breast cancer to improving survivorship. She wants to guide patient’s through their individual journey.
She sees patients in her High Risk Breast Clinic who are at an increased risk for breast cancer which can include having a family history of breast cancer, carrying a genetic mutation increasing the risk of breast cancer or having a prior breast biopsy that elevates ones risk for breast cancer. She also sees patients in her Breast Oncology Clinic who have a diagnosis of breast cancer and has a special interest in the management of breast cancer diagnosed during pregnancy.

Education and Training
  • BA, Human Biology, University of Kansas, Lawrence, Kansas
  • MD, Medicine, University of Kansas, Kansas City, Kansas
  • Residency, Internal Medicine, Northwestern University, Chicago, Illinois
  • Clinical Fellowship, Hematology and Oncology, Northwestern University, Chicago, Illinois
Licensure, Accreditations & Certifications
  • Internal Medicine, American Board of Internal Medicine
  • Medical License, Kansas State Board of Healing Arts
  • Medical Oncology, American Board of Internal Medicine
Professional Affiliations
  • Evolution KC: Changing Paradigms for Women Treating Women's Cancers, Chair, 2020 - Present
  • University of KS Medical Center, School of Medicine Research Committee, Member, 2019 - 2022
  • Southwest Oncology Group, Member, 2017 - Present
  • American Society of Clinical Oncology, Member, 2010 - Present

Research

Overview

Dr. Nye’s areas of research include breast cancer prevention and survivorship with current projects focusing on prevention in young women at high risk for breast cancer who are still considering pregnancy, for postmenopausal women who are experiencing hot flashes and weight loss interventions in women at high risk, genetic mutation carriers and breast cancer survivors. She also works with the breast cancer team to design and ensure clinical trials are available to our breast cancer patients requiring treatment.

Current Research and Grants
  • Analysis of Breast and Stool Microbiome in Premenopausal Women at High Risk for Breast Cancer, University of KS Cancer Center Pilot Award, PI, PI
  • Efficacy of Point of Service Testing in Breast Cancer (E-POST BC), Association of Community Cancer Centers and Pfizer
  • Feasibility Study of Moderate Dose Omega-3 Fatty Acid Supplementation in Premenopausal Women at High Risk for Breast Cancer and Considering Future Pregnancy, American Cancer Society IRG, PI, PI
  • Efficacy of Point of Service Testing in Metastatic Breast Cancer (E-POST-MBC), Myriad, Co-PI, Co-PI
  • Biomarker-Based Phase IIB Trial of (Bazedoxifene-Conjugated Estrogen) to Reduce Risk for Breast Cancer, National Institutes of Health/National Cancer Institute R01 CA249437-01A, Co-I, Co-I
  • Project BRA: Project ECHO Breast Cancer Risk Assessment, Komen Kansas and Western Missouri Community Grant, Co-PI, Co-PI
Publications
  • Sharma, Priyanka, Abramson, Vandana, O'Dea, Anne., P., Nye, Lauren., E., Mayer, Ingrid, Pathak, Harsh, Hoffmann, Marc, Stecklein, Shane, Elia, Manana, Lewis, Sharon, Scott, Jevinda, De Jong, Jilliann, Wang, Yen, Yoder, Rachel, Schwensen, Kelsey, Finke, Karissa, Heldstab, Jaimie, LaFaver, Stephanie, Williamson, Stephen, Phadnis, Milind, Reed, Gregory, Kimler, Bruce., F., Khan, Qamar, Godwin, Andrew. 2021. Clinical and Biomarker Results from Phase I/II Study of P13K Inhibitor Alpellsib plus Nab-Paclitaxel in HER2-Negative Metastatic Breast Cancer. Clinical Cancer Research, 27 (14), 3896-3904. https://clincancerres.aacrjournals.org/content/early/2021/06/01/1078-0432.CCR-20-4879
  • Fabian, C.., J., Klemp, J.., R., Marchello, N., Vidoni, E.., D., Sullivan, D.., K., Nydegger, J.., L., Phillips, T.., A., Kreutzjans, A.., L., Hendry, B., Befort, C.., A., Nye, L.., E., Powers, K.., R., Hursting, S.., D., Giles, E.., D., Hamilton-Reeves, J.., M., Li, B., Kimler, B.., F.. 2021. Rapid Escalation of High-Volume Exercise During Caloric Restriction; Change in Visceral Adipose Tissue and Adipocytokines in Obese Sedentary Breast Cancer Survivors. Cancers, 13 (19), 4871
  • Nye, Lauren., E.. 2020. Integrating Breast Cancer Risk Management into Primary Care. American Family Physician, 101 (6), 330-331. https://www.proquest.com/docview/2454212855?pq-origsite=gscholar&fromopenview=true |
  • Nye, Lauren., E.. 2020. Benign Breast Disease. Conn's Current Therapy, 1138-1142
  • Nye, L.., E., Takae, B.. 2020. Breast Cancer. Conn's Current Therapy, 1142-1146
  • Sharma, Priyanka, Kimler, Bruce., F., O'Dea, Anne., P., Nye, Lauren., E., Wang, Yen, Yoder, Rachel, Staley, Joshua, Prochaska, Lindsey, Wagner, Jamie, Amin, Amanda, Kelsey, Balanoff, Christa, Elia, Manana, Crane, Gregory, Madhusudhana, Sheshadri, Hoffmann, Marc, Sheehan, Maureen, Rodriguez, Roberto, Finke, Karissa, Shah, Rajvi, Satelli, Deepti, Shrestha, Anuj, Beck, Larry, McKittrick, Richard, Pluenneke, Robert, Raja, Vinay, Beeki, Venkatadri, Corum, Larry, Heldstab, Jaimie, LaFaver, Stephanie, Prager, Micki, Phadnis, Milind, Mudaranthakam, Dinesh., Pal, Jensen, Roy, Godwin, Andrew, Salgado, Roberto, Mehta, Kathan, Khan, Qamar. 2021. Randomized Phase II Trial of Anthracycline-free and Anthracycline-containing Neoadjuvant Carboplatin Chemotherapy Regimens in Stage I-III Triple-Negative Breast Cancer (NEOSTOP). Clinical Cancer Research, 27 (4), 975-982. https://clincancerres.aacrjournals.org/content/27/4/975
  • Larson, Kelsey., E., Wang, Yen., Y., Finke, Karissa, Yoder, Rachel, Schwensen, Kelsey, O'Dea, Anne., P., Qamar, Nye, Lauren., E., Heldstab, Jaimie, Godwin, Andrew., K., Kimler, Bruce., F., Sharma, Priyanka. 2020. Impact of Germline BRCA Mutation Status on Survival in Women with Metastatic Triple Negative Breast Cancer. Journal of Cancer Treatment and Research, 7, 81-86. https://www.researchgate.net/publication/338517006_Impact_of_Germline_BRCA_Mutation_Status_on_Survival_in_Women_with_Metastatic_Triple_Negative_Breast_Cancer
  • Fabian, C.., J., Nye, L.., E., Powers, K.., R., Nydegger, J.., L., Kreutzjans, A.., L., Phillips, T.., A., Metheny, T., Winblad, O., Zalles, C.., M., Hagan, C.., R., Goodman, M.., L., Gajewski, B.., J., Koestler, D.., C., Chalise, P., Kimler, B.., F.. 2019. Effect of Bazedoxifene and Conjugated Estrogen (Duavee) on Breast Cancer Risk Biomarkers in High-Risk Women: A Pilot Study.. Cancer Prevention Research, 12 (10), 711-720. https://cancerpreventionresearch.aacrjournals.org/content/12/10/711 | |