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Kyle R. Sweeney, MD

Kyle Sweeney portrait
Assistant Professor, Orthopedic Surgery and Sports Medicine

Professional Background

Dr. Kyle Sweeney completed a fellowship at the University of Chicago. He earned his medical degree from Vanderbilt University School of Medicine and completed his residency at Emory University. His professional mission is to provide education, treatment and support to patients and families, empowering them to take control of their medical care. The patient who finds their way into his office has been unexpectedly thrust down an unfamiliar road. Where two weeks prior they were walking the dog, engaged at work or planning the next family vacation, today they find themselves bouncing between doctor visits, MRIs or blood draws. In these difficult circumstances, how do people regain a sense of control? They do so by understanding their diagnosis, preparing for and overcoming inevitable challenges, and having an actionable plan moving forward. Although he takes a leading role, this process is not performed in a vacuum. Close coordination with medical oncologists, radiologists, pathologists and radiation oncologists ensures access to as many experts and treatment avenues as are available.

As a specialist in musculoskeletal oncology and reconstructive surgery, he is an expert in the diagnosis and treatment of cancer involving the bones and soft tissues in patients of all ages – from infants to octogenarians. He sees patients with sarcoma, bone cancer, benign bone tumors, benign soft tissue tumors and multiple myeloma. He also treats patients with metastatic cancers that attack bone such as breast cancer, prostate cancer, kidney cancer, lung cancer and thyroid cancer. Among the many types of procedures he performs, he is experienced in radical resections of sarcoma, limb salvage, joint reconstruction, rotationplasty and various treatment modalities for metastatic bone cancer. In addition to surgical procedures for cancer, he also performs hip and knee replacements in otherwise healthy patients with arthritis and other conditions affecting their mobility and quality of life.

Education and Training
  • BS, Double Major: Human Biology and Human Physiology, Michigan State University, Michigan
  • MD, Medicine, Vanderbilt University School of Medicine, Nashville, TN
  • Residency, Orthopedics, Emory University Department of Orthopedic Surgery, Atlanta, Georgia
  • Clinical Fellowship, Musculoskeletal Oncology, University of Chicago Department of Orthopaedic Surgery, Chicago, Illinois
Licensure, Accreditations & Certifications
  • Board Certified, Orthopaedic Surgery, American Board of Orthopaedic Surgery
  • Kansas Medical License, University Of Kansas Health System
Professional Affiliations
  • Kansas Orthopaedic Society, Vice President, 2023 - Present
  • Musculoskeletal Tumor Society, Education Committee, Member, 2023 - Present
  • Patient Safety and Quality Subcommittee of the GMEC, Patient Safety and Quality Subcommittee of the GMEC, Member, 2021 - Present
  • Musculoskeletal Oncology Research Initiative , Board of Directors - Member-at-Large, 2019 - Present
  • Musculoskeletal Tumor Society, MSTS Website Committee, Member, 2019 - 2019
  • Kansas Orthopaedic Society, Member, 2018 - Present
  • Musculoskeletal Oncology Research Initiative , Member, 2018 - Present



My research is predominantly clinical and involves the perioperative care of orthopaedic oncology patients. Of special interest is the impact and efficacy of tranexamic acid on perioperative blood loss and blood transfusion rates.

Current Research and Grants
  • Local Bisphosphonate Effect on Recurrence Rate in Extremity Giant Cell Tumor of Bone: A Prospective Randomized Controlled Trial, St. Louis University, Co-I
  • Hughes, Nicole, Birlingmair, Jacob, Baker, Jordan, Grace, Sweeney, Kyle. 2022. Evaluating factors affecting length of hospital stay in patients with metastatic bone tumors. Journal of Orthopaedics, 29, 28-30.
  • Haase, Doug, Kimbrel, Brandon, Bombardier, Brendan, Mersereau, Erik, Templeton, Kimberly, Sweeney, Kyle. 2022. Tranexamic Acid Improves Early Postoperative Mobilization in Cancer Patients Undergoing Endoprosthetic Reconstruction. Journal of Surgical Oncology, 125 (8), 1318-1325
  • Haase, Douglas, Bombarbier, Brandon, Templeton, Kimberly, Rosenthal, Howard, Sweeney, Kyle. 2021. Tranexamic Acid in Cancer Patients Undergoing Endoprosthetic Reconstruction – A Cost Analysis. J Am Acad of Orthop Surg, 29 (22), 961-969
  • Bombardier, Brandon, Haase, Douglas, Friedman, Elizabeth, Tanner, Hughes, Nicole, Sweeney, Kyle. 2021. A Comparison of Necrosis Among Adjuvant Therapies Used for the Treatment of Benign Bone Tumors. J Surg Onc, 123 (5), 1299-1303