Ethan Alexander, M.D.

Professional Background

Dr. Ethan Alexander is an endocrinologist and clinical lipidologist at The University of Kansas Medical Center. Originally from the Kansas City area, he attended the University of Kansas School of Medicine for both for medical school and internal medicine residency. Getting involved in lipoprotein research and the metabolic management of cardiovascular disease in residency, he then went on to complete a fellowship in Endocrinology, Metabolism, and Diabetes at the University of Kansas.
His clinical and research focus is on cardiometabolic health and improving outcomes for patients with genetic dyslipidemia, premature cardiovascular disease, and diabetes. He is involved in multiple research efforts ranging from basic science to clinical trials in the world of lipidology and cardiometabolic health and is heavily involved in medical student, resident, and fellow teaching.

• BA, Biology, MidAmerica Nazarene University, Olathe, Kansas
• MD, Medicine , University of Kansas School of Medicine, Kansas City, Kansas
• Internship, Internal Medicine, University of Kansas School of Medicine, Kansas City, Kansas
• Residency, Internal Medicine, University of Kansas , Kansas City, Kansas
• Clinical Fellowship, Endocrinology, Metabolism, and Diabetes, University of Kansas School of Medicine, Kansas City, Kansas

• Endocrine Society, Member, 2020 - Present
• National Lipid Association, Member, 2020 - Present
• International Society for Apheresis, Member, 2019 - Present

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Research

Overview

Dr. Alexander is involved in multiple research efforts ranging from basic science to clinical trials in the world of lipidology and cardiometabolic health and is heavily involved in medical student, resident, and fellow teaching.

• A Double-Blind, Randomized, Placebo-controlled, Multicenter Study Assessing the Impact of Olpasiran on Major Cardiovascular Events in Patients with Atherosclerotic Cardiovascular Disease and Elevated Lipoprotein(a)- OCEAN(a), Amgen
• A Phase 3 Randomized, Placebo-Controlled Clinical Study to Evaluate the Efficacy and Safety of MK-0616 in Reducing Major Adverse Cardiovascular Events in Participants in High Cardiovascular Risk., Merck
• A randomized double-blind, placebo-controlled, multicenter trial assessing the impact of lipoprotein(a) lowering with TQJ230 on major cardiovascular events in patients with established cardiovascular disease, Novartis
• A Randomized, Double-Blind, Placebo-Controlled, Phase 3 Study if AKCEA-APOCIII-LRX Administered Subcutaneously to Patients with Familial Chylomicronemia Syndrome (FCS), Ionic
• A Randomized, Double-Blind, Placebo-Controlled, Phase 3 Study of ISIS 678354 Administered Subcutaneously to Patients with Severe Hypertriglyceridemia, ISIS
• A Randomized, Double-Blind, Placebo-Controlled, Phase 3 Study of Olezarsen (ISIS 678354) in Patents with Hypertriglyceridemia and Atherosclerotic Cardiovascular Disease (Established or at Increased Risk for), or with Severe Hypertriglyceridemia., ISIS
• An Open-Label Extension Study of AKCEA-APOCIII-LRx Administered Subcutaneously to Patients with Familial Chylomicronemia Syndrome (FCS), ISIS
• An Open-Label Extension study of Olezarsen (ISIS 678354) Administered Subcutaneously to Patients with Severe Hypertriglyceridemia (SHTG), ISIS

• Alexander, Ethan , Cristiano, Elizabeth, Miles, John . 2022. Diabetic Dyslipidemia: a Major and Treatable Contributor to Cardiovascular Disease in Type 2 Diabetes
• Alexander, Ethan, Moriarty, Patrick., M., Wilk, Barry, Eliaz, Isaac. 2021. Establishing low‐density lipoprotein apheresis tolerability in patients with prior anaphylactoid reactions to lipoprotein apheresis using magnesium sulfate. Journal of Clinical Apheresis, 36 (3), 437-442. https://doi.org/10.1002/jca.21884
• Quick, Benjamin, Alexander, Ethan, Ramm, Bethany, Rachford, Wallace, Quinlan, Janelle, Broxterman, Jane. 2020. Multidisciplinary approach to maximise continuity in an academic internal medicine resident clinic. BMJ Open Quality, 9 (2), e000841. https://doi.org/10.1136/bmjoq-2019-000841
• Alexander, Ethan, Cristiano, Elizabeth, Miles, John., M.. 2022. Precision Medicine for Diabetes and Dyslipidemia, 65-87. https://doi.org/10.1007/978-3-030-98927-9_3
• Shaukat, Arslan, Waheed, Salman, Alexander, Ethan, Washko, Daniel, Dawn, Buddhadeb, Olyaee, Mojtaba, Gupta, Kamal. 2018. Etiology of gastrointestinal bleeding in patients on dual antiplatelet therapy. Journal of Digestive Diseases, 19 (2), 66-73. https://doi.org/10.1111/1751-2980.12575
• Sreedhara, Padmini, Czerwinski, Vincent, Alexander, Ethan, Choudhary, Chitra. 2023. T-cell Lymphoblastic Lymphoma Presenting as a Pituitary Mass. JCEM Case Reports, 1 (5). https://doi.org/10.1210/jcemcr/luad097