Dong Pei, Ph.D.

Professional Background

Dr. Dong Pei is a Research Assistant Professor in the Department of Biostatistics and Data Science. Dr. Pei joined the University of Kansas Medical Center in after the completion of his doctoral training in Biology (emphasis in Bioinformatics) at New Mexico State University. His research focus on the development and application of bioinformatics tools/pipelines to analyze high-throughput 'omic data.

• BS, Aquaculture, China Agricultural University
• PhD, Biology, New Mexico State University

Research

Overview

My research interests involve the development and application of bioinformatics tools/pipelines to analyze high-throughput 'omic data, including: DNAseq, RNAseq, scRNAseq, Infinium Methylation microarray, etc. Most of my previous and ongoing research efforts have focused on studying the genetic alterations in model organisms and the application of novel bioinformatics/statistical methodologies to elucidate the molecular mechanisms underlying disease development and progression. In addition to my research activities, I also provide leadership in high-performance computing to the Department of Biostatistics and Data Science as co-Manager of the Biostatistics group that is a member of the KU Community Cluster operated by the Center for Research Computing at KU-Lawrence.

• Michaud, Dominique., S, Ruan, Mengyuan, Koestler, Devin., C, Pei, Dong, Marsit, Carmen., J, De Vivo, Immaculata, Kelsey, Karl., T. 2020. Epigenome-wide association study using prediagnostic bloods identifies new genomic regions associated with pancreatic cancer risk. JNCI Cancer Spectrum
• Michaud, Dominique., S, Ruan, Mengyuan, Koestler, Devin., C, Alonso, Lola, Molina-Montes, Esther, Pei, Dong, Marsit, Carmen., J, De Vivo, Immaculata, Malats, Nuria, Kelsey, Karl., T. 2020. DNA methylation derived immune cell profiles, CpG markers of inflammation, and pancreatic cancer risk. Cancer Epidemiology and Prevention Biomarkers
• Seng, Amara, Krausz, Kelsey., L, Pei, Dong, Koestler, Devin., C, Fischer, Ryan., T, Yankee, Thomas., M, Markiewicz, Mary., A. 2020. Coexpression of FOXP3 and a Helios isoform enhances the effectiveness of human engineered regulatory T cells. Blood advances, 4 (7), 1325--1339
• Xu, Jiannong, Pei, Dong, Nicholson, Ainsley, Lan, Yuhao, Xia, Qing. 2019. In Silico Identification of Three Types of Integrative and Conjugative Elements in Elizabethkingia anophelis Strains Isolated from around the World. mSphere, 4 (2), e00040--19
• Zaimi, Ina, Pei, Dong, Koestler, Devin., C, Marsit, Carmen., J, De Vivo, Immaculata, Tworoger, Shelley., S, Shields, Alexandra., E, Kelsey, Karl., T, Michaud, Dominique., S. 2018. Variation in DNA methylation of human blood over a 1-year period using the Illumina MethylationEPIC array. Epigenetics, 1--16
• Mudaranthakam, Dinesh., Pal, Thompson, Jeffrey, Hu, Jinxiang, Pei, Dong, Chintala, Shanthan., Reddy, Park, Michele, Fridley, Brooke., L, Gajewski, Byron, Koestler, Devin., C, Mayo, Matthew., S. 2018. A Curated Cancer Clinical Outcomes Database (C3OD) for accelerating patient recruitment in cancer clinical trials. JAMIA Open
• Cooper, Michael., A, McCoin, Colin, Pei, Dong, Thyfault, John., P, Koestler, Devin, Wright, Douglas., E. 2018. Reduced mitochondrial reactive oxygen species production in peripheral nerves of mice fed a ketogenic diet. Experimental physiology
• Hyter, Stephen, Hirst, Jeff, Pathak, Harsh, Pessetto, Ziyan., Y, Koestler, Devin., C, Raghavan, Rama, Pei, Dong, Godwin, Andrew., K. 2018. Developing a genetic signature to predict drug response in ovarian cancer. Oncotarget, 9 (19), 14828
• Pei, Dong, Nicholson, Ainsley., C, Jiang, Jinjin, Chen, Huiying, Whitney, Anne., M, Villarma, Aaron, Bell, Melissa, Humrighouse, Ben, Rowe, Lori., A, Sheth, Mili, others. 2017. Complete Circularized Genome Sequences of Four Strains of Elizabethkingia anophelis, Including Two Novel Strains Isolated from Wild-Caught Anopheles sinensis. Genome announcements, 5 (47), e01359--17