Dinesh Pal I. Mudaranthakam, PhD, MBA

Professional Background

As an Assistant Professor and Director of Research Information Technology, I oversee and provide expertise in designing and implementing research databases and data warehouses. Cancer Curated Clinical Outcomes Database (C3OD) is an example of a data warehouse. C3OD is an intuitive user interface utilized by our physicians and research staff to perform feasibility analysis and trial recruitment. I have 12+ years of experience with database development and maintenance to execute multi-center clinical trials through various phases – study start-up, participant identification, recruitment, data collection, curation, quality analysis, data dissemination, and manuscript publication. Our team has gone through the rigorous validation process to get our Clinical Research Information System (CRIS) 21 CFR Part 11 compliant (prescribed by FDA).

• PhD, Health Policy & Management, University of Kansas Medical Center, Kansas City, Ks
• MBA, Leadership and Manangement, University of Kansas, Lawrance, Kansas
• MS, Computer Science, Kansas State University, Manhattan, Kansas
• Other, Computer Science, Jawaharlal Nehru Technology University, Hyderabad, Telengana

• Tableau, Tableau

• Rural Health Center- Data and Informatics Committee, Data and Informatics Committee, Chair, 2023 - Present
• AcademyHealth, Member, 2021 - Present

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Research

Overview

Research interests: Population health, epidemiology, electronic health records, administrative claims data, observational study design, categorical data analysis, survival analysis, longitudinal data, System integration, Informatics Eco-system

Current research areas include Financial Toxicity among Cancer Patients, Rural/Racial disparities, Informatics System integration, Clinical trial optimization. Our team has built an Informatics Eco-System combined with constructed in-house and 3rd party owned tools. Each system within the ecosystem helps expedite the research process and facilities that an individual research team performs on an extensive scheme of things. The crucial element has been integrated to avoid data discrepancy and the elimination of double data entry.

• Mudaranthakam, D., P, Thompson, J, Hu, J, Pei, D, Chintala, S., R, Park, M, Fridley, B., L, Gajewski, B, Koestler, D., C, Mayo, M., S. 2018. A Curated Cancer Clinical Outcomes Database (C3OD) for accelerating patient recruitment in cancer clinical trials.. JAMIA open, 1 (2), 166-171
• Mudaranthakam, Dinesh., Pal, Phadnis, Milind., A., Krebill, Ron, Clark, Lauren, Wick, Jo., A., Thompson, Jeffrey, Keighley, John, Gajewski, Byron., J., Koestler, Devin., C., Mayo, Matthew., S.. 2020. Improving the efficiency of clinical trials by standardizing processes for Investigator Initiated Trials. CONTEMPORARY CLINICAL TRIALS COMMUNICATIONS, 18
• Mudaranthakam, Dinesh., Pal, Harlan-Williams, Lisa., M., Jensen, Roy., A., Kuo, Hanluen, Garimella, Vandita, Chen, Ronald., C., Mayo, Matthew., S., Krebill, Hope. 2020. OPTIK: a database for understanding catchment areas to guide mobilization of cancer center assets. DATABASE-THE JOURNAL OF BIOLOGICAL DATABASES AND CURATION
• Mudaranthakam, Dinesh., Pal, Cernik, Colin, Curtis, Leslie, Griffith, Blake, Hu, Jinxiang, Wick, Jo, Thompson, Jeffrey, Gajewski, Byron, Koestler, Devin, Jensen, Roy., A., Mayo, Matthew., S.. 2020. Utilization of Technology to Improve Efficiency in Investigational Drug Management Processes. JOURNAL OF PHARMACY TECHNOLOGY, 36 (2), 84-90
• Fabian, C., J, Mudaranthakam, D., P. 2023. Reduced-Frequency Endocrine Therapy and Challenges of Noninferiority Study Designs.. JAMA oncology. https://jamanetwork.com/journals/jamaoncology/fullarticle/2802830
• Mudaranthakam, Dinesh., Pal, Shergina, Elena, Park, Michele, Thompson, Jeffrey, Streeter, David, Hu, Jinxiang, Wick, Jo, Gajewski, Byron, Koestler, Devin., C., Godwin, Andrew., K., Jensen, Roy., A., Mayo, Matthew., S.. 2019. Optimizing Retrieval of Biospecimens Using the Curated Cancer Clinical Outcomes Database (C3OD). CANCER INFORMATICS, 18
• Barohn, R., J, Gajewski, B, Pasnoor, M, Brown, A, Herbelin, L., L, Kimminau, K., S, Mudaranthakam, D., P, Jawdat, O, Dimachkie, M., M, Iyadurai, S, Stino, A, Kissel, J, Pascuzzi, R, Brannagan, T, Wicklund, M, Ahmed, A, Walk, D, Smith, G, Quan, D, Heitzman, D, Tobon, A, Ladha, S, Wolfe, G, Pulley, M, Hayat, G, Li , Y, Thaisetthawatkul, P, Lewis, R, Biliciler, S, Sharma, K, Salajegheh, K, Trivedi, J, Mallonee, W, Burns, T, Jacoby, M, Bril, V, Vu, T, Ramchandren, S, Bazant, M, Austin, S, Karam, C, Hussain, Y, Kutz, C, Twydell, P, Scelsa, S, Kushlaf, H, Wymer, J, Hehir, M, Kolb, N, Ralph, J, Barboi, A, Verma, N, Ahmed, M, Memon, A, Saperstein, D, Lou, J., S, Swenson, A, Cash, T. 2021. Patient Assisted Intervention for Neuropathy: Comparison of Treatment in Real Life Situations (PAIN-CONTRoLS): Bayesian Adaptive Comparative Effectiveness Randomized Trial.. JAMA neurology, 78 (1), 68-76
• Sharma, P, Kimler, B., F, O'Dea, A., P, Nye, L, Wang, Y., Y, Yoder, R, Staley, J., M, Prochaska, L, Wagner, J, Amin, A., L, Larson, K, Balanoff, C, Elia, M, Crane, G, Madhusudhana, S, Hoffmann, M, Sheehan, M, Rodriguez, R, Finke, K, Shah, R., H, Satelli, D, Shrestha, A, Beck, L, McKittrick, R, Pluenneke, R, Raja, V, Beeki, V, Corum, L, Heldstab, J, LaFaver, S, Prager, M, Phadnis, M, Mudaranthakam, D., P, Jensen, R., A, Godwin, A., K, Salgado, R, Mehta, K, Khan, Q., J. 2020. Randomized phase II trial of anthracycline-free and anthracycline-containing neoadjuvant carboplatin chemotherapy regimens in stage I-III triple-negative breast cancer (NeoSTOP).. Clinical cancer research : an official journal of the American Association for Cancer Research
• Cernik, Colin, Fife, John, Thompson, Jeffrey, Harlan-Williams, Lisa, Mudaranthakam, Dinesh., Pal. 2020. Publications search optimization: Comparison of a homegrown-API approach versus manual publication searches at an NCI designated cancer center. HEALTH INFORMATICS JOURNAL, 26 (4), 3066-3071
• Milling, T., J, Warach, S, Johnston, S., C, Gajewski, B., J, Costantini, T, Price, M, Wick, J, Roward, S, Mudaranthakam, D, Dula, A., N, King, B, Muddiman, A, Lip, G. 2021. Restart TICrH Trial Design: an adaptive randomized trial of time intervals to restart direct oral anticoagulants after traumatic intracranial hemorrhage.. Journal of neurotrauma