Lexie Brown, Ph.D.

Professional Background

I have worked collaboratively with KUMC research teams in project development, database design, data monitoring, data management, and statistical analyses for a variety of multisite randomized controlled trials. I successfully helped implement large, multisite trials, many funded by PCORI (Patient Centered Outcomes Research Institute), and applied a variety of statistical methods including Bayesian adaptive designs for comparative effectiveness research (PAIN-CONTRoLS, CER-1306-02496), a phase III trial (ADORE, 1R01HD083292), as well as a cluster randomized trial for weight loss (REPOWER, OB-1402-09413). Along with colleagues in the KUMC Department of Biostatistics & Data Science, I have formed trusted relationships with many PIs and research teams. Some of my time has also included expanding my research to statistics education, where I developed and instruct statistics-related courses to graduate students. This teaching experience has augmented my ability to discuss and communicate key statistical and methodological concepts to those whose background is not in statistics or data management. I work with and provide statistical expertise for many graduate student research projects. .

• BS, Statistics, University of Missouri-Kansas City, Kansas City, Missouri
• MS, Biostatistics, University of Kansas Medical Center, Kansas City, Kansas
• PhD, Biostatistics, University of Kansas Medical Center, Kansas City, Kansas

• SAS

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• Brown, Alexandra., R, Gajewski, Byron., J, Mudaranthakam, Dinesh, Pasnoor, Mamatha, Dimachkie, Mazen, Jawdat, Omar, Herbelin, Laura, Mayo, Matthew., S, Barohn, Richard., J. 2023. Conducting a Bayesian Multi-Armed Trial with Response Adaptive Randomization for Comparative Effectiveness of Medications for CSPN. Contemp Clin Trials Commun, 36, 101220. https://www.ncbi.nlm.nih.gov/pubmed/37965484/
• Brown, A., R, Gajewski, B., J, Aaronson, L., S, Mudaranthakam, D., P, Hunt, S., L, Berry, S., M, Quintana, M, Pasnoor, M, Dimachkie, M., M, Jawdat, O, Herbelin, L, Barohn, R., J. 2016. A Bayesian comparative effectiveness trial in action: developing a platform for multisite study adaptive randomization.. Trials, 17 (1), 428. https://www.ncbi.nlm.nih.gov/pubmed/27577191/
• Leavens ELS, Mayo, M., S, Brown, A., R, Cox, L., S, Ellerbeck, E., F, Ahluwalia, J., S, Nollen, N., L. 2023. Early Treatment Response in Black Smokers Undergoing Pharmacotherapy for Smoking Cessation: A Secondary Analysis of a Randomized Clinical Trial.. JAMA Netw Open, 6 (9), e2334695. https://www.ncbi.nlm.nih.gov/pubmed/37728930/
• Lambart, Leah, Nollen, Nicole., L., Mayo, Matthew., S., Funk, Olivia, Leavens, Eleanor, Cruvinel, Erica, Brown, Alexandra, Ahluwalia, Jasjit., S., Sanderson Cox, Lisa. 2024. The impact of blunt use on smoking abstinence among Black adults: Secondary analysis from randomized controlled smoking cessation clinical trial. Addictive Behaviors, 148, 107877. https://doi.org/10.1016/j.addbeh.2023.107877
• Gajewski, B., J, Carlson, S., E, Brown, A., R, Mudaranthakam, D., P, Kerling, E., H, Valentine, C., J. 2022. The value of a two-armed Bayesian response adaptive randomization trial.. J Biopharm Stat, 33 (1), 43-52. https://www.ncbi.nlm.nih.gov/pubmed/36411742/
• Desouza, Cyrus., V., Johnson‐Rabbett, Brianna., E., Gajewski, Byron, Brown, Alexandra, Ellerbeck, Edward., F., VanWormer, Jeffrey., J., Befort, Christie. 2022. The effect of nonpharmaceutical weight‐loss interventions in rural patients with diabetes: RE‐POWER Diabetes. Obesity, 30 (4), 884-892. https://doi.org/10.1002/oby.23392
• Gustafson, K., M, Christifano, D., N, Hoyer, D, Schmidt, A, Carlson, S., E, Colombo, J, Mathis, N., B, Sands, S., A, Chollet-Hinton, L, Brown, A., R, Mudaranthakam, D., P, Gajewski, B., J. 2021. Prenatal docosahexaenoic acid effect on maternal-infant DHA-equilibrium and fetal neurodevelopment: a randomized clinical trial.. Pediatr Res, 14 (16). https://www.ncbi.nlm.nih.gov/pubmed/34552200/
• Rubenstein, D, Aston, E., R, Nollen, N., L, Mayo, M., S, Brown, A., R, Ahluwalia, J., S. 2020. Factors Associated With Cannabis Use Among African American Nondaily Smokers.. J Addict Med, 14 (5), e170-e174. https://www.ncbi.nlm.nih.gov/pubmed/32187115/
• Carlson, S., E, Gajewski, B., J, Valentine, C., J, Sands, S., A, Brown, A., R, Kerling, E., H, Crawford, S., A, Buhimschi, C., S, Weiner, C., P, Cackovic, M, DeFranco, E., A, Mudaranthakam, D., P, Rogers, L., K. 2023. Early and late preterm birth rates in participants adherent to randomly assigned high dose docosahexaenoic acid (DHA) supplementation in pregnancy . Clin Nutr, 42 (2), 235-243. https://www.ncbi.nlm.nih.gov/pubmed/36680919/
• Carlson, S., E, Gajewski, B., J, Valentine, C., J, Kerling, E., H, Weiner, C., P, Cackovic, M, Buhimschi, C., S, Rogers, L., K, Sands, S., A, Brown, A., R, Mudaranthakam, D., P, Crawford, S., A, DeFranco, E., A. 2021. Higher dose docosahexaenoic acid supplementation during pregnancy and early preterm birth: A randomised, double-blind, adaptive-design superiority trial.. EClinicalMedicine, 36, 100905