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Amanda E. Brinker, PhD

Amanda Brinker portrait
Research Assistant Professor, Cancer Biology
abrinker2@kumc.edu

Professional Background

Research Assistant Professor
Director, Lead Development andamp; Optimization Shared Resource, University of Kansas
Deputy Director, Institute for Advancing Medical Innovation, University of Kansas

Assistant Director of Translational Sciences, University of Kansas
Cancer Biology
Ph.D. University of Kansas Medical Center, 2017


Research

Overview

Research InterestsDr. Brinker's research interests span the gamut of translational research from early small molecule screening through to IND-Enabling studies and facilitating public private partnerships for promising new therapeutics. Dr. Brinker's research focuses on developing therapeutics for cancers across the lifespan as well as rare diseases.
Academic RolesDr. Brinker is currently the Deputy Director of a unique drug discovery-based group called the Institute for Advancing Medical Innovation (IAMI) as well as the Assistant Director of Translational Sciences at the University of Kansas Cancer Center. She direct product development focused translational research within our NCI designated Cancer Center, as well as with our external for-profit and not-for-profit partners. IAMI recruits multi-disciplinary teams of bench scientists, clinical researchers, and statisticians to evaluate and advance promising therapeutics from early concept to clinical trials, ie: bench-to-bedside. In concert with these roles, Dr. Brinker serves as the Director for the Lead Development and Optimization Shared Resource which provides our researchers with high throughput screening, medicinal chemistry, as well as pharmacodynamics / pharmacokinetics, drug delivery and formulation, and bioanalytical chemistry expertise. Utilizing the three arms of the LDOSR (1 - High Throughput Screening Group, 2 - Medicinal Chemistry Group, 3 - Biotechnology Innovation andamp; Optimization Center), our researchers have an industry standard pipeline system which efficiently advances new discoveries to clinical proof-of-concept. Additionally, Dr. Brinker co-chairs the Drug Discovery and Development Steering Committee which provides a forum for faculty to vet their discovery projects and grants with a team of experts across the development and translational spectrum, while facilitating collaborations and access to shared resources.