Return to Boards Review Page

Wolf's Down and Dirty

Download a copy of this study guide (MS-Word)


Return to top

DISEASES

Addison's Disease primary adrenocortical deficiency
Addisonian Anemia pernicious anemia (antibodies to intrinsic factor or parietal cells ----> IF ----> Vit B12 ----> megaloblastic anemia)
Albright's Syndrome polyostotic fibrous dysplasia, precocious puberty, café au lait spots, short stature, young girls
Alport's Syndrome hereditary nephritis with nerve deafness
Alzheimer's progressive dementia
Argyll-Robertson Pupil loss of light reflex constriction (contralateral or bilateral)

"Prostitute's Eye" - accommodates but does not react

Pathognomonic for 3°Syphilis

Arnold-Chiari Malformation cerebellar tonsil herniation
Barrett's columnar metaplasia of lower esophagus (- risk of adenocarcinoma)
Bartter's Syndrome hyperreninemia
Becker's Muscular Dystrophy similar to Duchenne, but less severe (deficiency in dystrophin protein)
Bell's Palsy CNVII palsy (entire face; recall that UMN lesion only affects lower face)
Berger's Disease IgA nephropathy
Bernard-Soulier Disease defect in platelet adhesion (abnormally large platelets & lack of platelet-surface glycoprotein)
Berry Aneurysm circle of Willis (subarachnoid bleed)

often associated with ADPKD

Bowen's Disease carcinoma in situ on shaft of penis (- risk of visceral ca)
Briquet's Syndrome somatization disorder

psychological: multiple physical complaints without physical pathology

Broca's Aphasia Motor Aphasia intact comprehension
Brown-Sequard hemisection of cord (contralateral loss of pain & temp / ipsilateral loss of fine touch, UMN)
Bruton's Disease X-linked agammaglobinemia
Budd-Chiari post-hepatic venous thrombosis
Buerger's Disease acute inflammation of small, medium arteries ----> painful ischemia ----> gangrene
Burkitt's Lymphoma small noncleaved cell lymphoma EBV

8:14 translocation

Caisson Disease gas emboli
Chagas' Disease Trypansoma infection sleeping disease, cardiomegaly with apical atrophy, achlasia
Chediak-Higashi Disease Phagocyte Deficiency: neutropenia, albinism, cranial & peripheral neuropathy

repeated infections

Conn's Syndrome primary aldosteronism
Cori's Disease glycogen storage disease (debranching enzyme deficiency)
Creutzfeldt-Jakob prion infection ----> cerebellar & cerebral degeneration
Crigler-Najjar Syndrome congenital hyperbilirubinemia (unconjugated)

glucuronyl transferase deficiency

Crohn's IBD; ileocecum, transmural, skip lesions, lymphocytic infiltrate, granulomas

(contrast to UC: limited to colon, mucosa & submucosa, crypt abscesses, pseudopolyps, - colon cancer risk)

Curling's Ulcer acute gastric ulcer associated with severe burns
Cushing's Disease: hypercorticism 2° to - ACTH from pituitary (basophilic adenoma)

Syndrome: hypercorticism of all other causes (1° adrenal or ectopic)

Cushing's Ulcer acute gastric ulcer associated with CNS trauma
de Quervain's Thyroiditis self-limiting focal destruction (subacute thyroiditis)
DiGeorge's Syndrome thymic hypoplasia ----> T-cell deficiency

hypoparathyroidism

Down's Syndrome trisomy 21 or translocation
Dressler's Syndrome Post-MI Fibrinous Pericarditis autoimmune
Dubin-Johnson Syndrome congenital hyperbilirubinemia (conjugated)

striking brown-to-black discoloration of the liver

Duchenne Muscular Dystrophy deficiency of dystrophin protein ----> MD X-linked recessive
Edwards' Syndrome trisomy 18

rocker-bottom feet, low ears, heart disease

Ehler's-Danlos defective collagen
Eisenmenger's Complex late cyanotic shunt (R®L) pulmonary HTN & RVH 2° to long-standing VSD, ASD, or PDA
Erb-Duchenne Palsy trauma to superior trunk of brachial plexus Waiter's Tip
Ewing Sarcoma undifferentiated round cell tumor of bone
Eyrthroplasia of Queyrat carcinoma in situ on glans penis
Fanconi's Syndrome impaired proximal tubular reabsorption 2° to lead poisoning or Tetracycline (glycosuria, hyperphosphaturia, aminoaciduria, systemic acidosis)
Felty's Syndrome rheumatoid arthritis, neutropenia, splenomegaly
Gardner's Syndrome adenomatous polyps of colon plus osteomas & soft tissue tumors
Gaucher's Disease Lysosomal Storage Disease glucocerebrosidase deficiency

hepatosplenomegaly, femoral head & long bone erosion, anemia

Gilbert's Syndrome benign congenital hyperbilirubinemia (unconjugated)
Glanzmann's Thrombasthenia defective glycoproteins on platelets
Goodpasture's autoimmune: ab's to glomerular & alveolar basement membranes
Grave's Disease autoimmune hyperthyroidism (TSI)
Guillain-Barre idiopathic polyneuritis (ascending muscle weakness & paralysis; usually self-limiting)
Hamman-Rich Syndrome idiopathic pulmonary fibrosis
Hand-Schuller-Christian chronic progressive histiocytosis
Hashimoto's Thyroiditis autoimmune hypothyroidism
Hashitoxicosis initial hyperthyroidism in Hashimoto's Thyroiditis that precedes hypothyroidism
Henoch-Schonlein purpura hypersensivity vasculitis

hemmorhagic urticaria (with fever, arthralgias, GI & renal involvement)

associated with upper respiratory infections

Hirschprung's Disease aganglionic megacolon
Horner's Syndrome ptosis, miosis, anhidrosis (lesion of cervical sympathetic nerves often 2° to a Pancoast tumor)
Huntington's progressive degeneration of caudate nucleus, putamen & frontal cortex; AD
Jacksonian Seizures epileptic events originating in the primary motor cortex (area 4)
Job's Syndrome immune deficiency: neutrophils fail to respond to chemotactic stimuli
Kaposi Sarcoma malignant vascular tumor (HHV8 in homosexual men)
Kartagener's Syndrome immotile cilia 2° to defective dynein arms infection, situs inversus, sterility
Kawasaki Disease mucocutaneous lymph node syndrome (lips, oral mucosa)
Klinefelter's Syndrome 47, XXY
Kluver-Bucy bilateral lesions of amygdala (hypersexuality; oral behavior)
Krukenberg Tumor adenocarcinoma with signet-ring cells (typically originating from the stomach) metastases to the ovaries
Laennec's Cirrhosis alcoholic cirrhosis
Lesch-Nyhan HGPRT deficiency

gout, retardation, self-mutilation

Letterer-Siwe acute disseminated Langerhans' cell histiocytosis
Libman-Sacks endocarditis with small vegetations on valve leaflets

associated with SLE

Lou Gehrig's Amyotrophic Lateral Sclerosis degeneration of upper & lower motor neurons
Mallory-Weis Syndrome bleeding from esophagogastric lacerations 2° to wretching (alcoholics)
Marfan's connective tissue defect
McArdle's Disease glycogen storage disease (muscle phosphorylase deficiency)
Meckel's Diverticulum rule of 2's: 2 inches long, 2 feet from the ileocecum, in 2% of the population

embryonic duct origin; may contain ectopic tissue (gastric, pancreatic, etc.)

Meig's Syndrome Triad: ovarian fibroma, ascites, hydrothorax
Menetrier's Disease giant hypertrophic gastritis (enlarged rugae; plasma protein loss)
Monckeberg's Arteriosclerosis calcification of the media (usually radial & ulnar aa.)
Munchausen Syndrome factitious disorder (consciously creates symptoms, but doesn't know why)
Nelson's Syndrome 1° Adrenal Cushings ----> surgical removal of adrenals ----> loss of negative feedback to pituitary ® Pituitary Adenoma
Niemann-Pick Lysosomal Storage Disease sphingomyelinase deficiency

"foamy histiocytes"

Osler-Weber-Rendu Syndrome Hereditary Hemorrhagic Telangiectasia
Paget's Disease abnormal bone architecture (thickened, numerous fractures ----> pain)
Pancoast Tumor bronchogenic tumor with superior sulcus involvement ----> Horner's Syndrome
Parkinson's dopamine depletion in nigrostriatal tracts
Peutz-Jegher's Syndrome melanin pigmentation of lips, mouth, hand, genitalia plus hamartomatous polyps of small intestine
Peyronie's Disease subcutaneous fibrosis of dorsum of penis
Pick's Disease progressive dementia similar to Alzheimer's
Plummer's Syndrome hyperthyroidism, nodular goiter, absence of eye signs (Plummer's = Grave's - eye signs)
Plummer-Vinson esophageal webs & iron-deficiency anemia, - SCCA of esophagus
Pompe's Disease glycogen storage disease ----> cardiomegaly
Pott's Disease tuberculous osteomyelitis of the vertebrae
Potter's Complex renal agenesis ----> oligohydramnios ----> hypoplastic lungs, defects in extremities
Raynaud's Disease: recurrent vasospasm in extremities

Phenomenon: 2° to underlying disease (SLE or scleroderma)

Reiter's Syndrome urethritis, conjunctivitis, arthritis non-infectious (but often follows infections), HLA-B27, polyarticular
Reye's Syndrome microvesicular fatty liver change & encephalopathy

2° to aspirin ingestion in children following viral illness

Riedel's Thyroiditis idiopathic fibrous replacement of thyroid
Rotor Syndrome congenital hyperbilirubinemia (conjugated)

similar to Dubin-Johnson, but no discoloration of the liver

Sezary Syndrome leukemic form of cutaneous T-cell lymphoma (mycosis fungoides)
Shaver's Disease aluminum inhalation ----> lung fibrosis
Sheehan's Syndrome postpartum pituitary necrosis
Shy-Drager parkinsonism with autonomic dysfunction & orthostatic hypotension
Simmond's Disease pituitary cachexia
Sipple's Syndrome MEN type IIa (pheochromocytoma, thyroid medulla, parathyroid)
Sjogren's Syndrome triad: dry eyes, dry mouth, arthritis - risk of B-cell lymphoma
Spitz Nevus juvenile melanoma (always benign)
Stein-Leventhal polycystic ovary
Stevens-Johnson Syndrome erythema multiforme, fever, malaise, mucosal ulceration (often 2° to infection or sulfa drugs)
Still's Disease juvenile rheumatoid arthritis (absence of rheumatoid factor)
Takayasu's arteritis aortic arch syndrome

loss of carotid, radial or ulnar pulses

Tay-Sachs gangliosidosis (hexosaminidase A deficiency ----> GM2 ganglioside)
Tetralogy of Fallot ÊVSD, Ëoverriding aorta, Ìpulmonary artery stenosis, Íright ventricular hypertrophy
Tourette's Syndrome involuntary actions, both motor and vocal
Turcot's Syndrome adenomatous polyps of colon plus CNS tumors
Turner's Syndrome 45, XO
Vincent's Infection "trench mouth" - acute necrotizing ulcerative gingivitis
von Gierke's Disease glycogen storage disease (G6Pase deficiency)
von Hippel-Lindau hemangioma (or hemangioblastoma)

adenomas of the viscera, especially renal cell carcinoma

von Recklinghausen's neurofibromatosis & café au lait spots
von Recklinghausen's Disease of Bone osteitis fibrosa cystica ("brown tumor") 2° to hyperparathyroidism
von Willebrand's Disease defect in platelet adhesion 2° to deficiency in vWF
Waldenstrom's macroglobinemia proliferation of IgM-producing lymphoid cells
Wallenberg's Syndrome Posterior Inferior Cerebellar Artery (PICA) thrombosis "Medullary Syndrome"

Ipsilateral: ataxia, facial pain & temp; Contralateral: body pain & temp

Waterhouse-Friderichsen catastrophic adrenal insufficiency 2° to hemorrhagic necrosis (eg, DIC)

often 2° to meningiococcemia

Weber's Syndrome Paramedian Infarct of Midbrain

Ipsilateral: mydriasis; Contralateral: UMN paralysis (lower face & body)

Wegener's Granulomatosis necrotizing granulomatous vasculitis of paranasal sinuses, lungs, kidneys, etc.
Weil's Disease leptospirosis
Wermer's Syndrome MEN type I (thyroid, parathyroid, adrenal cortex, pancreatic islets, pituitary)
Wernicke's Aphasia Sensory Aphasia impaired comprehension
Wernicke-Korsakoff Syndrome thiamine deficiency in alcoholics; bilateral mamillary bodies (confusion, ataxia, ophthalmoplegia)
Whipple's Disease malabsorption syndrome (with bacteria-laden macrophages) & polyarthritis
Wilson's Disease hepatolenticular degeneration (copper accumulation & decrease in ceruloplasmin)
Wiskott-Aldrich Syndrome immunodeficiency: combined B- &T-cell deficiency (thrombocytopenia & eczema)
Wolff-Chaikoff Effect high iodine level (--)'s thyroid hormone synthesis
Zenker's Diverticulum esophageal; cricopharyngeal muscles above UES
Zollinger-Ellison gastrin-secreting tumor of pancreas (or intestine) ----> - acid ----> intractable ulcers


Return to top

HALLMARK FINDINGS

Albumino-Cytologic Dissociation Guillain-Barre (markedly increased protein in CSF with only modest increase in cell count)
Antiplatelet Antibodies idiopathic thrombocytopenic purpura
Arachnodactyly Marfan's
Aschoff Bodies rheumatic fever
Auer Rods acute promyelocytic leukemia (AML type M3)
Autosplenectomy sickle cell anemia
Babinski UMN lesion
Basophilic Stippling of RBCs lead poisoning
Bence Jones Protein multiple myeloma free light chains (either kappa or lambda)

Waldenstrom's macroglobinemia

Birbeck Granules histiocytosis X (eosinophilic granuloma)
Blue Bloater Chronic Bronchitis
Boot-Shaped Heart Tetralogy of Fallot
Bouchard's Nodes osteoarthritis (PIP)
Boutonniere's Deformity rheumatoid arthritis
Brown Tumor hyperparathyroidism
Brushfield Spots Down's
Call-Exner Bodies granulosa cell tumor
Cardiomegaly with Apical Atrophy Chagas' Disease
Chancre 1° Syphilis
Chancroid Haemophilus ducreyi
Charcot Triad multiple sclerosis (nystagmus, intention tremor, scanning speech)
Charcot-Leyden Crystals bronchial asthma
Cheyne-Stokes Breathing cerebral lesion
Chocolate Cysts endometriosis
Chvostek's Sign Hypocalcemia facial spasm in tetany
Clue Cells Gardnerella vaginitis
Codman's Triangle osteosarcoma
Cold Agglutinins Mycoplasma pneumoniae

infectious mononucleosis

Condyloma Lata 2° Syphilis

new coffee flavor at Bagel & Bagel

Cotton Wool Spots HTN
Councilman Bodies dying hepatocytes
Crescents In Bowman's Capsule rapidly progressive (crescentic glomerulonephritis)
Currant-Jelly Sputum Klebsiella
Curschmann's Spirals bronchial asthma
Depigmentation Of Substantia Nigra Parkinson's
Donovan Bodies granuloma inguinale (STD)
Eburnation osteoarthritis (polished, ivory-like appearance of bone)
Ectopia Lentis Marfan's
Erythema Chronicum Migrans Lyme Disease
Fatty Liver Alcoholism
Ferruginous Bodies asbestosis
Ghon Focus / Complex Tuberculosis (1° & 2°, respectively)
Gower's Maneuver Duchenne's MD use of arms to stand
Heberden's Nodes Osteoarthritis (DIP)
Heinz Bodies G6PDH Deficiency
Hemorrhagic Urticaria Henoch-Schonlein
Heterophil Antibodies infectious mononucleosis (EBV)
Hirano Bodies Alzheimer's
Hypersegmented PMNs Megaloblastic anemia
Hypochromic Microcytic RBCs iron-deficiency anemia
Jarisch-Herxheimer Reaction Syphilis over-aggressive treatment of an asymptomatic pt. that causes symptoms 2° to rapid lysis
Joint Mice osteoarthritis (fractured osteophytes)
Kaussmaul Breathing acidosis
Keratin Pearls SCCA
Keyser-Fleischer Ring Wilson's
Kimmelstiel-Wilson Nodules diabetic nephropathy
Koilocytes HPV
Koplik Spots measles
Lewy Bodies Parkinson's (eosinophilic inclusions in damaged substantia nigra cells)
Lines of Zahn arterial thrombus
Lisch Nodules neurofibromatosis (von Recklinhausen's disease)
Lumpy-Bumpy IF Glomeruli poststreptococcal glomerulonephritis
McBurney's Sign appendicitis (McBurney's Point is 2/3 of the way from the umbilicus to anterior superior iliac spine)
Michealis-Gutmann Bodies Malakoplakia
Monoclonal Antibody Spike multiple myeloma this is called the M protein (usually IgG or IgA)

MGUS

Myxedema hypothyroidism
Negri Bodies rabies
Neuritic Plaques Alzheimer's
Neurofibrillary Tangles Alzheimer's
Non-pitting Edema Myxedema

Anthrax Toxin

Notching of Ribs Coarctation of Aorta
Nutmeg Liver CHF
Painless Jaundice pancreatic CA (head)
Pannus rheumatoid arthritis
Pautrier's Microabscesses mycosis fungoides (cutaneous T-cell lymphoma)
Philadelphia Chromosome CML

ALL

Pick Bodies Pick's Disease
Pink Puffer Emphysema Centroacinar ­ smoking Panacinar - a1-antitrypsin deficiency
Podagra gout (MP joint of hallux)
Port-Wine Stain Hemangioma
Posterior Anterior Drawer Sign tearing of the ACL
Psammoma Bodies Papillary adenocarcinoma of the thyroid

Serous papillary cystadenocarcinoma of the ovary

Meningioma

Mesothelioma

Pseudohypertrophy Duchenne muscular dystrophy
Punched-Out Bone Lesions multiple myeloma
Rash on Palms & Soles 2° Syphilis

RMSF

Red Morning Urine paroxysmal nocturnal hemoglobinuria
Reed-Sternberg Cells Hodgkin's Disease
Reid Index Increased chronic bronchitis
Reinke Crystals Leydig cell tumor
Rouleaux Formation multiple myeloma RBC's stacked as poker chips
S3 Heart Sound L®R Shunt (VSD, PDA)

Mitral Regurg

LV Failure

S4 Heart Sound Pulmonary Stenosis

Pulmonary HTN

Schwartzman Reaction Neisseria meningitidis impressive rash with bugs
Simian Crease Down's
Smith Antigen SLE (also anti-dsDNA)
Soap Bubble on X-Ray giant cell tumor of bone
Spike & Dome Glomeruli membranous glomerulonephritis
String Sign on X-ray Crohn's bowel wall thickening
Target Cells Thalassemia
Tendinous Xanthomas Familial Hypercholesterolemia
Thyroidization of Kidney chronic pyelonephritis
Tophi gout
Tram-Track Glomeruli membranoproliferative glomerulonephritis
Trousseau's Sign visceral ca, classically pancreatic (migratory thrombophlebitis)

hypocalcemia (carpal spasm)

These are two entirely different disease processes and different signs, but they unfortunately have the same name.

Virchow's Node supraclavicular node enlargement by metastatic carcinoma of the stomach
Warthin-Finkeldey Giant Cells Measles
WBC Casts pyelonephritis
Wire Loop Glomeruli lupus nephropathy, type IV
- AFP in amniotic fluid or mother's serum Spina Bifida

Anencephaly

- Uric Acid Gout

Lesch Nyhan

Myeloproliferative Disorders

Diuretics (Loop & Thiazides)

FEV1/FVC COPD


Return to top

MOST COMMON

1° Tumor arising from bone in adults Multiple Myeloma
Adrenal Medullary Tumor ­ Adults Pheochromocytoma
Adrenal Medullary Tumor ­ Children Neuroblastoma
Bacterial Meningitis ­ adults Neisseria meningitidis
Bacterial Meningitis ­ elderly Strep pneumoniae
Bacterial Meningitis ­ newborns E. coli
Bacterial Meningitis ­ toddlers Hib
Bone Tumors Metasteses from Breast & Prostate
Brain Tumor ­ Child Medulloblastoma (cerebellum)
Brain Tumor ­Adult Astrocytoma (including Glioblastoma Multiforme) then: mets, meningioma, Schwannoma
Breast Carcinoma Invasive Duct Carcinoma
Breast Mass Fibrocystic Change (Carcinoma is the most common is post-menopausal women)
Bug in Acute Endocarditis Staph aureus
Bug in debilitated, hospitalized pneumonia pt Klebsiella
Bug in Epiglottitis Hib
Bug in GI Tract Bacteroides (2nd ­ E. coli)
Bug in IV drug user bacteremia / pneumonia Staph aureus
Bug in PID N. Gonnorrhoeae
Bug in Subacute Endocarditis Strep Viridans
Cardiac 1° Tumor ­ Adults Myxoma "Ball Valve"
Cardiac 1° Tumor ­ Child Rhabdomyoma
Cardiac Tumor ­ Adults Metasteses
Cardiomyopathy Dilated (Congestive) Cardiomyopathy
Cause of 2° HTN Renal Disease
Cause of Addison's Autoimmune (2nd ­ infection)
Cause of Congenital Adrenal Hyperplasia 21-Hydroxylase Deficiency (then, 11-)
Cause of Cushings Exogenous Steroid Therapy (then, 1° - ACTH, Adrenal Adenoma, Ectopic ACTH)
Cause of death in Alzheimer pts Pneumonia
Cause of death in Diabetics MI
Cause of Death in SLE pts. Lupus Nephropathy Type IV (Diffuse Proliferative)
Cause of Dementia Alzheimer's
Cause of Dementia (2nd most common) Multi-Infarct Dementia
Cause of food poisoning Staph aureus
Cause of mental retardation Down's
Cause of mental retardation (2nd most common) Fragile X
Cause of preventable blindness Chlamydia
Cause of Pulmonary HTN COPD
Cause of SIADH Small Cell Carcinoma of the Lung
Chromosomal disorder Down's
Congenital cardiac anomaly VSD (membranous > muscular)
Congenital early cyanosis Tetralogy of Fallot
Coronary Artery thrombosis LAD
Demyelinating Disease Multiple Sclerosis
Dietary Deficiency Iron
Disseminated opportunistic infection in AIDS CMV (Pneumocystis carinii is most common overall)
Esophageal cancer SCCA
Fatal genetic defect in Caucasians Cystic Fibrosis
Female Tumor Leimyoma
Form of Amyloidosis Immunologic (Bence Jones protein in multiple myeloma is also called the Amyloid Light Chain)
Form of Tularemia Ulceroglandular
Gynecologic malignancy Endometrial Carcinoma
Heart Murmur Mitral Valve Prolapse
Heart Valve in bacterial endocarditis Mitral
Heart Valve in bacterial endocarditis in IV drug users Tricuspid
Heart Valve involved in Rheumatic Fever Mitral then Aortic
Hereditary Bleeding Disorder Von Willebrand's Disease
Liver 1° Tumor Hepatoma
Liver Disease Alcoholic Liver Disease
Location of Adult brain tumors Above Tentorium
Location of Childhood brain tumors Below Tentorium
Lysosomal Storage Disease Gaucher's
Motor Neuron Disease ALS
Neoplasm ­ Child Leukemia
Neoplasm ­ Child (2nd most common) Medulloblastoma of brain (cerebellum)
Nephrotic Syndrome Membranous Glomerulonephritis
Opportunistic infection in AIDS PCP
Ovarian Malignancy Serous Cystadenoma
Ovarian Tumor Hamartoma
Pancreatic Tumor Adeno (usually in the head)
Patient with ALL / CLL / AML / CML ALL - Child / CLL - Adult over 60 / AML - Adult over 60 / CML - Adult 35-50
Patient with Goodpasture's Young male
Patient with Reiter's Male
Pituitary Tumor Prolactinoma (2nd ­ Somatotropic "Acidophilic" Adenoma)
Primary Hyperparathyroidism Adenomas (followed by: hyperplasia, then carcinoma)
Pt. With Hodgkin's Young Male (except Nodular Sclerosis type ­ Female)
Pt. With Minimal Change Disease Young Child
Secondary Hyperparathyroidism Hypocalcemia of Chronic Renal Failure
Sexually transmitted disease Chlamydia
Site of Diverticula Sigmoid Colon
Site of metastasis Regional Lymph Nodes
Site of metastasis (2nd most common) Liver
Sites of atherosclerosis Abdominal aorta > coronary > popliteal > carotid
Skin Cancer Basal Cell Carcinoma
Stomach cancer Adeno
Testicular Tumor Seminoma
Thyroid Cancer Papillary Carcinoma
Tracheoesophageal Fistula Lower esophagus joins trachea / upper esophagus ­ blind pouch
Tumor of Infancy Hemangioma
Type of Hodkin's Mixed Cellularity (versus: lymphocytic predominance, lymphocytic depletion, nodular sclerosis)
Type of Non-Hodgkin's Follicular, small cleaved
Vasculitis (of medium & small arteries) Temporal Arteritis
Viral Encephalitis HSV
Worm infection in US Pinworm (2nd ­ Ascaris)


Return to top

SIGNATURE DRUG TOXICITIES

Agranulocytosis Clozapine
Aplastic Anemia Chloramphenicol

NSAIDs

Benzene

Atropine-like Side Effects Tricyclics
Cardiotoxicity Doxorubicin

Daunorubicin

Cartilage Damage in children Fluoroquinolones (Ciprofloxacin & Norfloxacin)
Cinchonism Quinidine
Cough ACE Inhibitors
Diabetes Insipidus Lithium
Disulfiram-like effect Metronidazole

Sulfonylureas (1st generation)

Extrapyramidal Side Effects Antipsychotics (Thioridazine, Haloperidol, Chlorpromazine)
Fanconi's Syndrome Tetracycline
Fatal Hepatotoxicity (necrosis) Valproic Acid

Halothane

Acetaminophen

Gingical Hyperplasia Phenytoin
Gray Baby Syndrome Chloramphenicol
Gynecomastia Cimetidine

Azoles

Spironolactone

Digitalis

Hemolytic Anemia in G6PD-deficiency Sulfonamides

Isoniazid

Aspirin

Ibuprofen

Primaquine

Hepatitis Isoniazid
Hot Flashes, Flushing Niacin

Tamoxifen

Ca++ Channel Blockers

Induce CP450 Barbiturates

Phenytoin

Carbamazepine

Rifampin

Inhibit CP450 Cimetidine

Ketoconazole

Interstitial Nephritis Methicillin

NSAIDs (except Aspirin)

Furosemide

Sulfonamides

Monday Disease Nitroglycerin Industrial exposure ----> tolerance during week ----> loss of tolerance during weekend ----> headache, tach, dizziness upon re-exposure
Orange Body Fluids Rifampin
Osteoporosis Heparin

Corticosteroids

Positive Coombs' Test Methyldopa
Pulmonary Fibrosis Bleomycin

Amiodarone

Red Man Syndrome Vancomycin
Severe HTN with Tyramine MAOIs
SLE-like Syndrome Procainamide

Hydralazine

Tardive Dyskinesia Antipsychotics (Thioridazine, Haloperidol, Chlorpromazine)
Tinnitus Aspirin

Quinidine


Return to top

MISCELLANEOUS

Fastest growing tumor ­ Burkitt's

PE's are found in half of all autopsies

Courvoisier's Law: tumors that obstruct the common bile duct cause enlarged gallbladders, but obstructing gallstones do not (too much scarring).

Only DNA virus to replicate in cytoplasm: Pox

Only RNA virus to replicate in nucleus: Influenza

Bacillus anthracis has the only protein capsule

Bordetella pertussis (Whooping Cough) elicits lymphocytosis rather than granulocytosis

Bronchioalveolar carcinomas grow without destroying the normal architecture of the lung

Cryptococcus neoformans often lacks a capsule and, when stained with GMS, looks just like Pneumycistis carinii, except that Cryptococcus lacks the prominent nucleoli.


Return to top