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Sensory Nerve Disorder Lab

 

high magnification photomicrograph of a cross section through a muscle spindle

A high magnification confocal photomicrograph of a sensory neuron from a mouse dorsal root ganglion. The neuron has been stained for neurofilaments (green) only contained by myelinated neurons. A second stain has been used to determine if the neuron expresses a particular transcription factor, ATF3 (red). ATF3 is only expressed by DRG neurons after the peripheral axon has been damaged. The lab is interested in the molecular and cellular responses of DRG neurons to a variety of neuropathic diseases.