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Rural Engagement in Primary Care for Optimizing Weight Reduction (RE-POWER)

Christie Befort (PI): OB-1402-09413, 01/01/2015 - 12/31/2019

· PCORI/Patient-Centered Outcomes Research Institute
Our long term objective in this 3-state study is to develop an evidence-based and sustainable model for the treatment of obesity in primary care among rural residents who suffer disproportionately from obesity and obesity-related illnesses, including diabetes, heart disease, and arthritis.  Doctors and researchers from the University of Kansas Medical Center, University of Nebraska Medical Center and Marshfield Clinic in Wisconsin are teaming up to test three types of weight management programs in primary care offices throughout the rural Midwest.  Our scientific mission is to enhance access to effective weight loss programs and lifestyle interventions by discovering optimal ways for implementing them into healthcare settings.  Our clinical mission is to empower people to improve their health and well-being through scientifically driven and patient-centered programs that promote healthy eating, physical activity, and successful long-term weight control.

KUMC Collaborators:

  • Ann Davis, Behavioral Pediatrics
  • Edward Ellerbeck, Preventive Medicine
  • Byron Gajewski, Biostatistics
  • Allen Greiner, Family Medicine
  • Kim Kimminau, Family Medicine
  • Nikki Nollen, Preventive Medicine

Outside Collaborators:

  • Cyrus Desouza, University of Nebraska
  • Andjela Drincic, University of Nebraska
  • Leslie Eiland, University of Nebraska
  • Terry Huang, University of Nebraksa
  • Ram Pathak, Marshfield Clinic
  • Michael Perri, Univeristy of Florida
  • Jeff VanWormer, Marshfield Clinic

Group Phone-Based Weight Control among Rural Breast Cancer Survivors

Christie Befort (PI): R01 CA155014, 08/01/11 - 05/31/16
• NIH/National Cancer Institute
This behavioral RCT will compare the impact of group phone-based lifestyle intervention to mail-only intervention on weight loss maintenance, quality of life, and breast cancer biomarkers among rural breast cancer survivors.

KUMC Collaborators:

  • Carol Fabian, Breast Cancer Prevention Center
  • Jennifer Klemp, Breast Cancer Prevention Center
  • Francisco Diaz, Biostatistics
  • Theresa Shireman, Preventive Medicine
  • Debra Sullivan, Dietetics and Nutrition

Outside Collaborators:

  • Michael Perri, University of Florida
  • Katie Schmitz, University of Pennsylvania

Studies of Reward Processing in Nicotine Addiction and Obesity

• Laura Martin (PI): R00 DA025153, 09/15/10 - 07/31/14
• NIH/National Institute on Drug Abuse
Our goal is to examine neural responses during impulsive decision-making in nicotine addicted, obese and healthy groups using functional magnetic resonance imaging (fMRI).

Impacting Diet and Sedentary Behaviors in Adolescents through Handheld Computers

• Nikki Nollen (PI): K23 HL090496, 08/01/09 - 07/31/14
This study will test the feasibility and acceptability of a three-month intervention delivered to adolescents via handheld computer and explore three- and six-month changes in body mass index, fruit and vegetable consumption, TV/screen time, and sugar-sweetened beverages.

KUMC Collaborators:

  • Susan Carlson, Dietetics and Nutrition
  • Edward Ellerbeck, Preventive Medicine
  • Michael Rapoff, Pediatrics

Institutional Clinical and Translational Science Award, Pilot and Collaborative Studies Funding Program

• Richard Barohn (PI): UL1TR000001/TR000119/, 06/01/11 - 02/29/16

Reducing Sedentary Behavior to Prevent Weight Regain among Breast Cancer Survivors
• Christie Befort (PI), 03/01/13 - 02/28/14
Pilot RCT comparing standard weight loss maintenance intervention to the same intervention plus an additional sedentary behavior change component with device-based real time feedback on weight and insulin changes among breast cancer survivors.

The Impact of Exercise on Brain Responses to Smoking Cues
• Laura Martin (PI), 03/01/13 - 02/28/14 
The goal of this project is to identify brain responses to smoking cues in light smokers. Achieving this objective will provide an understanding of smoking reward among light smokers. We will test the working hypothesis that light smokers are more responsive to smoking cues than non-smoking cues.

Moderate Intensity Exercise as an Adjunct to Smoking Cessation Treatment for African American Women
• Nikki Nollen (PI), 03/01/13 - 02/28/14
The objective of this project is to develop and pilot a moderate intensity exercise program (150 min/week) that obtains high rates of exercise adherence and facilitates quitting when delivered as an adjunct to our standard 7-week smoking cessation intervention (bupropion and behavioral counseling) for AA women.

Rural Lifestyle Eating and Activity Program

• Michael Perri (PI, University of Florida), R18 HL112720, 08/15/13 - 04/30/18
We propose to conduct a single-blind, randomized controlled "effectiveness" trial in obese adults (N=540) to evaluate the effects of extended-care programs delivered via individual or group telephone counseling, compared to a health education control (CTRL) condition, on long-term (22-month) changes in body weight.

  • Department Role: Christie Befort, PI of subaward

Neuroimaging Studies of Reward, Impulsivity, and Adherence to an Exercise Program

• Cary Savage (PI, KUMC - Center for Health Behavior Neuroscience): R01 DK085605, 04/01/10 - 01/31/15
Prospective study to identify impulsivity characteristics and related brain activation as predictors of adherence to a supervised exercise intervention among obese adults.

  • Department Role: Christie Befort, Co-Investigator; Laura Martin, Co-Investigator

Promoting Walking in African Americans with Peripheral Arterial Disease

• Tracie Collins (PI, KUMC - Wichita Preventive Medicine): R01 HL098909, 05/01/10 - 04/30/15
The overall objective of this application is to determine the efficacy of our PACE protocol, enhanced by adding motivational interviewing and culturally sensitive print material, to improve lower limb function in African Americans with peripheral arterial disease.

  • Department Role: Nikki Nollen, Co-Investigator
Last modified: Jun 30, 2019