Wen Zhao

Graduate Student - Hagenbuch Lab
B.S. Bioinformatics, Huazhong University of Science and Technology, Wuhan, China


I came from Hubei province in China. After I got my Bachelor degree in Bioinformatics at Huazhong University of Science and Technology, I continued my graduate study and received a master degree in Biochemistry and Molecular Biology in 2010. After one year IGPBS training, I joined the laboratory of Dr. Bruno Hagenbuch in the spring of 2011 to pursue my Ph.D. degree in Pharmacology.


Research Interests

The disposition of xenobiotics is largely dependent on drug transporters. The expression of transporters differs between genders and species and therefore could potentially lead to gender- and species- dependent clearance of xenobiotics. Perfluoroalkyl substances (PFASs) are environmental contaminants that possess such a gender-, species- and chain length-dependent elimination pattern in animal models and humans. Published studies indicate that drug transporters might play a role. So I am interest in identifying and characterizing specific kidney and liver transporters involved in the renal elimination and hepatic accumulation of PFASs and hence explaining some of the observed toxicokinetic phenomena. My other project is to identify the physiological driving force of organic anion transporting polypeptide 1B3 (OATP1B3) using plasma membrane vesicles.

Last modified: Sep 07, 2013

wzhao

Contact

Wen Zhao
Graduate Student - Hagenbuch Lab

4021 HLSIC; MS1018
3901 Rainbow Blvd.
Kansas City, Kansas 66160

P: (913) 588-9189
F: (913) 588-7501
wzhao@kumc.edu

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