Prachi Borude

Graduate Student - Apte Lab
B. Pharmacy, Pune University, India
M.Tech. , U.D.C.T. , Mumbai, India


I received Bachelor degree in Pharmacy from N.D.M.V.P.S' College of Pharmacy, Nashik, India (Pune University) and Master of Technology in Bioprocess Technology from U.D.C.T. Mumbai, India (Mumbai University). After completing Master I worked as a junior manager for 2 years in Dr. Reddy's lab Ltd and Wockhardt Ltd in bio-therapeutics downstream processing group. In 2010 I joined Dr. Apte's lab at KUMC as a research assistant and worked there for 2 years.


Research interest

Currently, I am pursuing my PhD in Dr. Udayan Apte's lab. My research focuses on identifying biomarkers of liver regeneration following Acetaminophen (APAP) overdose induced Acute liver failure (ALF). Liver regeneration is a major deciding factor in final outcome of APAP induced ALF so it is crucial to identify easily measurable and reliable biomarkers of liver regeneration. I am also studying role of hepatic progenitor cells in liver regeneration after APAP induced ALF.


Selected Publications

Prachi Borude*, Bharat Bhushan*, Genea Edwards, Chad Walesky, Joshua Cleveland, Feng Li, Xiaochao Ma and Udayan Apte (2013) Role of bile acids in liver injury and regeneration following acetaminophen overdose. Am. J. Pathol. (in Press)

Walesky C, Edwards G, Borude P, Gunewardena S, O'Neil M, Yoo B, Apte U. (2013) Hepatocyte nuclear factor 4 alpha deletion promotes diethylnitrosamine-induced hepatocellular carcinoma in rodents. Hepatology 2013 Jun (PMID: 23315968)

Walesky C, Gunewardena S, Terwilliger EF, Edwards G, Borude P, Apte U. (2013) Hepatocyte-specific deletion of hepatocyte nuclear factor-4α in adult mice results in increased hepatocyte proliferation.Am J Physiol Gastrointest Liver Physiol. 2013 Jan 1 (PMID: 23104559)

Borude P, Edwards G, Walesky C, Li F, Ma X, Kong B, Guo GL, Apte U. (2012) Hepatocyte-specific deletion of farnesoid X receptor delays but does not inhibit liver regeneration after partial hepatectomy in mice. Hepatology. 2012 Dec (PMID: 22730081)

Ni HM, Boggess N, McGill MR, Lebofsky M, Borude P, Apte U, Jaeschke H, Ding WX. (2012) Liver-specific loss of Atg5 causes persistent activation of Nrf2 and protects against acetaminophen-induced liver injury. Toxicol Sci. 2012 Jun (PMID: 22491424)

Valte RD, Borude PC, Hule AK, Juvekar AR. (2010) Optimization of xylanase production from Aspergillus foetidus MTCC 4898 by solid state fermentation using statistical methods. J Gen Appl Microbiol. 2010 Feb (PMID: 20339224)

Last modified: Jul 30, 2013

Prachi Borude

Contact

Prachi Borude
Graduate Student - Apte Lab

4052 HLSIC; MS 1018
3901 Rainbow Blvd.
Kansas City, Kansas 66160

P: (913) 945-6821
F: (913) 588-7501
pborude@kumc.edu

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