Graduate Student - Jaeschke Lab
Bachelor of Clinical Medicine, Zhengzhou University. Zhengzhou, China
Master of Clinical Medicine, Zhengzhou University. Zhengzhou, China
I come from Kaifeng, China and got my Bachelor and Master degree in Clinical Medicine from Zhengzhou University, During my graduate studies, I studied one year in Sweden at Goteborg University, where I focused on the inflammatory changes in neonatal brain injury. After graduation, I attended the IGPBS program of KUMC in 2014 and joined Dr. Jaeschke's lab a year later.
Acetaminophen (APAP) overdose is currently the most frequent cause of acute liver failure in USA. Nonparenchymal cells of the liver and infiltrating inflammatory cells may be involved in APAP hepatotoxicity. However, in contrast to the widely accepted contribution of inflammatory cells in the pathophysiology of hepatic ischaemia-reperfusion injury, and obstructive cholestasis, the contribution of inflammation in the mechanism of APAP-induced liver injury is highly controversial, a better understanding of the role of inflammation function during APAP hepatotoxicity will lead to novel treatment strategies.
Bi D, Qiao L, Bergelson I, Ek CJ, Duan L, Zhang X, Albertsson AM, Pettengill M, Kronforst K, Ninkovic J, Goldmann D, Janzon A, Hagberg H, Wang X, Mallard C, Levy O. Staphylococcus epidermidis Bacteremia Induces Brain Injury in Neonatal Mice via Toll-like Receptor 2-Dependent and -Independent Pathways. J Infect Dis. 2015 Apr 15. pii: jiv231.
Albertsson AM, Bi D, Duan L, Zhang X, Leavenworth JW, Qiao L, Zhu C, Cardell S, Cantor H, Hagberg H, Mallard C, Wang X. The immune response after hypoxia-ischemia in a mouse model of preterm brain injury. J Neuroinflammation. 2014 Sep 5;11:153.