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Jephte Akakpo

Graduate Student - Jaeschke Lab


My name is Jephte Akakpo and I completed a MSc degree in biological engineering.  Since August 2016, I am a graduate student in toxicology in the Department of Pharmacology, Toxicology and Therapeutics at the University of Kansas Medical Center. My goal is to become a translational toxicologist in the field of drug hepatotoxicity and acute liver failure.

Research interest
My research interest focuses on understanding the molecular and cellular mechanisms of acetaminophen (APAP) hepatotoxicity, which is the main cause of acute liver failure in western countries. My thesis work, which is supported by an F31 grant from NIH, involves both basic mechanistic studies of the role of mitochondrial biogenesis in APAP-induced liver injury and translational efforts to repurpose existing drugs for clinical use in APAP overdose. Currently I am working on 4-methylpyrazole, an FDA approved drug for methanol and ethylene glycol poisoning as a complement to the standard of care, N-acetyl cysteine.  


Bibliography

https://www.ncbi.nlm.nih.gov/myncbi/browse/collection/54946897/?sort=date&direction=ascending

Last modified: Mar 22, 2019

Jephte Akakpo

Contact

Jephte Akakpo
Graduate Student - Jaeschke Lab

4018 HLSIC; MS 1018
3901 Rainbow Blvd.
Kansas City, Kansas 66160

P: (913) 588-9184
jakakpo@kumc.edu

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