Ben Woolbright

Graduate Student - Jaeschke Lab
B.S. in Biology, University of Kansas, 2006


Born in Arkansas, but raised in Kansas, I graduated from the University of Kansas with a B.S. in Biology in 2006. I started my research career as a Ph.D. candidate in the Department of Pathology at Virginia Commonwealth University in the labs of Dr. Matthew Beckman, and subsequently Dr. Rakesh Kukreja, studying stem cell biology with the hope of enhancing the efficacy of stem cell transplantation therapy. I recently moved back to Kansas City to continue my education in the lab of Dr. Hartmut Jaeschke, pursuing a degree in Toxicology.

Research Interests

My interests scientifically are typically whatever I am doing in the moment. I enjoy Science more because of the process and the pursuit rather than for any one single interest. My hope is to be able to make a significant contribution to the field in some area that will directly impact quality of life for mankind.

Currently I am involved in a number of projects in the Jaeschke lab, however my main interest lies in the role of the neutrophil in cholestatic injury. Cholestasis is a part of multiple different pathologies including obstruction of the common bile duct, primary biliary cirrhosis, primary sclerosing cholangitis and intrahepatic familial cholestasis, and arises from different etiologies depending on which disease process is involved. While our lab has firmly established the neutrophil as a key mediator of cholestatic injury in extrahepatic cholestasis, we are currently trying to better define the role of the neutrophil in other models of cholestasis, as well as define new therapeutic targets for prevention of neutrophil mediated hepatic injury without complete immune suppression. To this end we employ multiple models of neutrophilic injury in the mouse, including surgical and nonsurgical models of cholestasis.

Publications

Benjamin L. Woolbright
, Youcai Zhang, Peter Fickert, Michael Trauner, Curtis D. Klaassen and Hartmut Jaeschke. Role of Neutrophils in Lithocholic Acid Induced Liver Injury in Mice. (To be submitted)

Jaeschke H and Woolbright BL. Current Strategies to Minimize Hepatic Ischemia-Reperfusion Injury by Targeting Reactive Oxygen Species. Transplantation Reviews. (Submitted)

Bajwa A, Forster MN, Maiti A, Woolbright BL, Beckman MJ. Specific Regulation of Cyp27B1and VDR in Proximal Versus Distal Renal Kidney Cells. Arch Biochem Biophys. 2008 Sep 1; 477(1):33-42

Last modified: Dec 04, 2012

bwoolbright

Contact

Ben Woolbright
Graduate Student - Jaeschke Lab

4020 HLSIC; MS 1018
3901 Rainbow Blvd.
Kansas City, Kansas 66160

P: (913) 588-9183
F: (913) 588-7501
bwoolbright@kumc.edu

ID=x9975