Pharmacology, Toxicology & Therapeutics
School of Medicine > Pharmacology, Toxicology & Therapeutics > COBRE > Success Stories
Success Stories
Since June 2006, 11 faculty have graduated from the COBRE when they obtained their own R01 or R56 grant from NIH.
Udayan Apte, Ph.D.
R01 Title: "Mechanisms of Liver Regeneration After Acetaminophen-Induced Acute Liver Failure"
Funded by: Diabetetes & Digestive & Kidney Diseases (NIDDK)
COBRE Mentors: Bryan Copple, Ph.D., Hartmut Jaeschke, Ph.D., and Steven Weinman, M.D., Ph.D.
Bryan Copple, Ph.D.
R01 Title: “Role of Early Growth Response Factor-1 in Cholestatic Liver Injury”
Funded by: Diabetetes & Digestive & Kidney Diseases (NIDDK)
COBRE Mentors: Curtis D. Klaassen, Ph.D. & Yu-Jui Yvonne Wan, Ph.D.
Wen-Xing Ding, Ph.D.
R01 Title: “Mechanisms Regulating Autophagy in Alcohol Induced Liver Injury”
Funded by: Alcohol Abuse & Alcoholism (NIAAA)
COBRE Mentors: Hartmut Jaeschke, Ph.D.. & Yu-Jui Yvonne Wan, Ph.D.
Grace Guo, Ph.D.
R01 Title: “Tissue specific mechanism of FXR in suppressing bile-acid synthesis”
Funded by: Diabetetes & Digestive & Kidney Diseases (NIDDK)
COBRE Mentors: Beth Levant, Ph.D. & Ken Peterson Ph.D.
Bruno Hagenbuch, Ph.D.
R01 Title: “Molecular Characterization of Hepatic Organic Anion Transporting Polypeptides”
Funded by: National Institute of General Medicine Sciences (NIGMS)
COBRE Mentors: Glen Andrews, Ph.D. & Curtis Klaassen, Ph.D.
Partha Kasturi, Ph.D.
R56 Title: "Role of mitochondrial protein ABCB6 in arsenic resistance"
Funded by: National Institute of Enviornmental Health Sciences (NIEHS)
COBRE Mentors: Bruno Hagenbuch, Ph.D. & Ken Peterson, Ph.D.
Tiangang Li, Ph.D.
R01 Title: "The role of hepatic Sortlin 1 in diabetic dyslipidemia"
Funded by: Diabetetes & Digestive & Kidney Diseases (NIDDK)
Research Mentors: Wen-Xing Ding, Ph.D. & Steven Weinman, M.D., Ph.D.
James Luyendyk, Ph.D.
R01 Title: “Mechanisms of xenobiotic-induced biliary inflammation and fibrosis”
Funded by: National Institute of Enviornmental Health Sciences (NIEHS)
COBRE Mentors: Hartmut Jaeschke, Ph.D. & Bao-Ting Zhu, Ph.D.
Xiaochao Ma, Ph.D.
R01 Title: “Mechanisms of adverse effects of anti-tuberculosis drugs”
Funded by: Diabetetes & Digestive & Kidney Diseases (NIDDK)
COBRE Mentors: Grace Guo, Ph.D. & Steven Weinman, M.D., Ph.D.
Li Wang, Ph.D.
R01 Title: “SHP regulation of lipid and lipoprotein metabolism"
Funded by: Diabetetes & Digestive & Kidney Diseases (NIDDK)
COBRE Mentors: Glen Andrews, Ph.D. & Curt Hagedorn, M.D.
Xiaobo Zhong, Ph.D.
R01 Title: “Control of developmental switch of Cyp3a gene expression in mouse liver”
Funded by: National Institute of General Medicine Sciences (NIGMS)
R01 Title: “Developmental Regulation of Drug Processing Genes”
Funded by: National Institute of Enviornmental Health Sciences (NIEHS)
COBRE Mentors: Curtis D. Klaassen, Ph.D. & Yu-Jui Yvonne Wan, Ph.D.