Peer reviewed publications that the ACL has contributed to:
Funk, R.S., Singh, R.K., Winefield, R.D., Kandel, S.E., Ruisinger, J.F., Moriarty, P.M., and Backes,, J.M. "Variability in Potency among Commercial Preparations of Berberine." (2017) J. Diet Suppl. doi: 10.1080/19390211
Chavan, H., Christudoss, P., Mickey, K., Tessman, R., Ni, H. M., Swerdlow, R., Krishnamurthy, P. (2017) "Arsenite effects on mitochondrial bioenergetics in human and mouse primary hepatocytes follows a non-linear dose response." Oxidative Medicine and Cellular Longevity. 2017:9251303.
Braghini, C.A., Costa, F.C., Fedosyuk, H., Neades, R.Y., Novikova, L.V., Parker, M.P., Winefield, R.D., Peterson, K.R. (2016) "Generation of non-deletional hereditary persistence of fetal hemoglobin β-globin locus yeast artificial chromosome transgenic mouse models: -175 Black HPFH and -195 Brazilian HPFH." Experimental biology and medicine (Maywood, N.J.). 241(7): 697-705
Pondugula, S. R., P. C. Flannery, U. Apte, J. R. Babu, T. Geetha, S. D. Rege, T. Chen and K. L. Abbott (2015). "Mg2+/Mn2+-dependent phosphatase 1A is involved in regulating pregnane X receptor-mediated cytochrome p450 3A4 gene expression." Drug Metab Dispos 43(3): 385-391.
Xie, Y., McGill, M.R., Cook, S.F., Sharpe, M.R., Winefield, R.D., Wilkins, D.G., Rollins, D.E., Jaeschke, H. (2015) "Time course of acetaminophen-protein adducts and acetaminophen metabolites in circulation of overdose patients" Xenobiotica 45(10): 921-929.
Winefield, R.D., Heemskerk, A.A., Kaul, S., Williams, T.D., Caspers, M.J., Prisinzano, T.E., McCance-Katz, E.F., Lunte, C.E., Faiman, M.D. (2015) "N-Acetyl-S-(N,N-diethylcarbamoyl) cysteine in rat nucleus accumbens, medial prefrontal cortex, and in rat and human plasma after disulfiram administration." Journal of Pharmaceutical and Biomedical Analysis.107: 518-525.
Bhushan, B., C. Walesky, M. Manley, T. Gallagher, P. Borude, G. Edwards, S. Du, K., C. D. Williams, M. R. McGill and H. Jaeschke (2014). "Lower susceptibility of female mice to acetaminophen hepatotoxicity: Role of mitochondrial glutathione, oxidant stress and c-jun N-terminal kinase." Toxicol Appl Pharmacol 281(1): 58-66.
Chavan, H., F. Li, R. Tessman, K. Mickey, K. Dorko, T. Schmitt, S. Kumer, S. Gunewardena, N. Gaikwad and P. Krishnamurthy (2015). "Functional coupling of ATP-binding cassette transporter Abcb6 to cytochrome P450 expression and activity in liver." J Biol Chem 290(12): 7871-7886.
Cheng, X., Y. Zhang and C. D. Klaassen (2014). "Decreased bile-acid synthesis in livers of hepatocyte-conditional NADPH-cytochrome P450 reductase-null mice results in increased bile acids in serum." J Pharmacol Exp Ther 351(1): 105-113.
Kong, B., J. Huang, Y. Zhu, G. Li, J. Williams, S. Shen, L. M. Aleksunes, J. R. Richardson, U. Apte, D. A. Rudnick and G. L. Guo (2014). "Fibroblast growth factor 15 deficiency impairs liver regeneration in mice." Am J Physiol Gastrointest Liver Physiol 306(10): G893-902.
Li, F., J. Lu and X. Ma (2014). "CPY3A4-mediated alpha-hydroxyaldehyde formation in saquinavir metabolism." Drug Metab Dispos 42(2): 213-220.
Li, J., L. Bi, M. Hulke and T. Li (2014). "Fish oil and fenofibrate prevented phosphorylation-dependent hepatic sortilin 1 degradation in Western diet-fed mice." J Biol Chem 289(32): 22437-22449.
Liang, N., C. Zhang, P. Dill, G. Panasyuk, D. Pion, V. Koka, M. Gallazzini, E. N. Olson, H. Lam, E. P. Henske, Z. Dong, U. Apte, N. Pallet, R. L. Johnson, F. Terzi, D. J. Kwiatkowski, J. Y. Scoazec, G. Martignoni and M. Pende (2014). "Regulation of YAP by mTOR and autophagy reveals a therapeutic target of tuberous sclerosis complex." J Exp Med 211(11): 2249-2263.
Liu, K., F. Li, J. Lu, S. Liu, K. Dorko, W. Xie and X. Ma (2014). "Bedaquiline metabolism: enzymes and novel metabolites." Drug Metab Dispos 42(5): 863-866.
McGill, M. R., F. Li, M. R. Sharpe, C. D. Williams, S. C. Curry, X. Ma and H. Jaeschke (2014). "Circulating acylcarnitines as biomarkers of mitochondrial dysfunction after acetaminophen overdose in mice and humans." Arch Toxicol 88(2): 391-401.
Manley, S., H. M. Ni, J. A. Williams, B. Kong, L. DiTacchio, G. Guo and W. X. Ding (2014). "Farnesoid X receptor regulates forkhead Box O3a activation in ethanol-induced autophagy and hepatotoxicity." Redox Biol 2C: 991-1002.
Monga, P. and U. Apte (2014). "Pro-regenerative signaling after acetaminophen-induced acute liver injury in mice identified using a novel incremental dose model." Am J Pathol 184(11): 3013-3025.
Ni, H. M., A. Bhakta, S. Wang, Z. Li, S. Manley, H. Huang, B. Copple and W. X. Ding (2014). "Role of hypoxia inducing factor-1beta in alcohol-induced autophagy, steatosis and liver injury in mice." PLoS One 9(12): e115849.
Ohnishi, S., A. Hays and B. Hagenbuch (2014). "Cysteine scanning mutagenesis of transmembrane domain 10 in organic anion transporting polypeptide 1B1." Biochemistry 53(14): 2261-2270.
Raveendran, V. V., K. M. Kassel, D. D. Smith, J. P. Luyendyk, K. J. Williams, R. Cherian, G. A. Reed, C. A. Flynn, I. L. Csanaky, A. L. Lickteig, M. J. Pratt-Hyatt, C. D. Klaassen and K. N. Dileepan (2014). "H1-antihistamines exacerbate high-fat diet-induced hepatic steatosis in wild-type but not in apolipoprotein E knockout mice." Am J Physiol Gastrointest Liver Physiol 307(2): G219-228.
Raveendran, V. V., D. D. Smith, X. Tan, M. E. Sweeney, G. A. Reed, C. A. Flynn, O. W. Tawfik, G. Milne and K. N. Dileepan (2014). "Chronic ingestion of H1-antihistamines increase progression of atherosclerosis in apolipoprotein E-/- mice." PLoS One 9(7): e102165.
Renaud, H. J., J. Y. Cui, H. Lu and C. D. Klaassen (2014). "Effect of diet on expression of genes involved in lipid metabolism, oxidative stress, and inflammation in mouse liver-insights into mechanisms of hepatic steatosis." PLoS One 9(2): e88584.
Saha, S. K., C. A. Parachoniak, K. S. Ghanta, J. Fitamant, K. N. Ross, M. S. Najem, S. Gurumurthy, E. A. Akbay, D. Sia, H. Cornella, O. Miltiadous, C. Walesky, V. Deshpande, A. X. Zhu, A. F. Hezel, K. E. Yen, K. S. Straley, J. Travins, J. Popovici-Muller, C. Gliser, C. R. Ferrone, U. Apte, J. M. Llovet, K. K. Wong, S. Ramaswamy and N. Bardeesy (2014). "Mutant IDH inhibits HNF-4alpha to block hepatocyte differentiation and promote biliary cancer." Nature 513(7516): 110-114.
Ward, J., C. Kanchagar, I. Veksler-Lublinsky, R. C. Lee, M. R. McGill, H. Jaeschke, S. C. Curry and V. R. Ambros (2014). "Circulating microRNA profiles in human patients with acetaminophen hepatotoxicity or ischemic hepatitis." Proc Natl Acad Sci U S A 111(33): 12169-12174.
Williams, C. D., M. R. McGill, M. Lebofsky, M. L. Bajt and H. Jaeschke (2014). "Protection against acetaminophen-induced liver injury by allopurinol is dependent on aldehyde oxidase-mediated liver preconditioning." Toxicol Appl Pharmacol 274(3): 417-424.
Woolbright, B. L., F. Li, Y. Xie, A. Farhood, P. Fickert, M. Trauner and H. Jaeschke (2014). "Lithocholic acid feeding results in direct hepato-toxicity independent of neutrophil function in mice." Toxicol Lett 228(1): 56-66.
Woolbright, B. L., M. R. McGill, V. S. Staggs, R. D. Winefield, P. Gholami, M. Olyaee, M. R. Sharpe, S. C. Curry, W. M. Lee, H. Jaeschke and G. Acute Liver Failure Study (2014). "Glycodeoxycholic acid levels as prognostic biomarker in acetaminophen-induced acute liver failure patients." Toxicol Sci 142(2): 436-444.
Zhang, Y., P. B. Limaye, H. J. Renaud and C. D. Klaassen (2014). "Effect of various antibiotics on modulation of intestinal microbiota and bile acid profile in mice." Toxicol Appl Pharmacol 277(2): 138-145.
Yang, M., A. Ramachandran, H. M. Yan, B. L. Woolbright, B. L. Copple, P. Fickert, M. Trauner and H. Jaeschke (2014). "Osteopontin is an initial mediator of inflammation and liver injury during obstructive cholestasis after bile duct ligation in mice." Toxicol Lett 224(2): 186-195.
Bhushan, B., P. Borude, G. Edwards, C. Walesky, J. Cleveland, F. Li, X. Ma and U. Apte (2013). "Role of bile acids in liver injury and regeneration following acetaminophen overdose." Am J Pathol 183(5): 1518-1526.
Bi, L., J. Y. Chiang, W. X. Ding, W. Dunn, B. Roberts and T. Li (2013). "Saturated fatty acids activate ERK signaling to downregulate hepatic sortilin 1 in obese and diabetic mice." J Lipid Res54(10): 2754-2762.
Fukui, M., K. S. Kang, K. Okada and B. T. Zhu (2013). "EPA, an omega-3 fatty acid, induces apoptosis in human pancreatic cancer cells: role of ROS accumulation, caspase-8 activation, and autophagy induction." J Cell Biochem114(1): 192-203.
Liu, J., Y. F. Lu, Y. Zhang, K. C. Wu, F. Fan and C. D. Klaassen (2013). "Oleanolic acid alters bile acid metabolism and produces cholestatic liver injury in mice." Toxicol Appl Pharmacol272(3): 816-824.
Li, F., J. Lu, J. Cheng, L. Wang, T. Matsubara, I. L. Csanaky, C. D. Klaassen, F. J. Gonzalez and X. Ma (2013). "Human PXR modulates hepatotoxicity associated with rifampicin and isoniazid co-therapy." Nat Med19(4): 418-420.
Ramachandran, A., M. R. McGill, Y. Xie, H. M. Ni, W. X. Ding and H. Jaeschke (2013). "Receptor interacting protein kinase 3 is a critical early mediator of acetaminophen-induced hepatocyte necrosis in mice." Hepatology58(6): 2099-2108.
Jiang, X. R., P. Wang, C. L. Smith and B. T. Zhu (2013). "Synthesis of novel estrogen receptor antagonists using metal-catalyzed coupling reactions and characterization of their biological activity." J Med Chem56(7): 2779-2790.
Walesky, C., S. Gunewardena, E. F. Terwilliger, G. Edwards, P. Borude and U. Apte (2013). "Hepatocyte-specific deletion of hepatocyte nuclear factor-4alpha in adult mice results in increased hepatocyte proliferation." Am J Physiol Gastrointest Liver Physiol304(1): G26-37.
Williams, C. D., M. R. McGill, A. Farhood and H. Jaeschke (2013). "Fas receptor-deficient lpr mice are protected against acetaminophen hepatotoxicity due to higher glutathione synthesis and enhanced detoxification of oxidant stress." Food Chem Toxicol58: 228-235.
Zhang, Y., I. L. Csanaky, F. P. Selwyn, L. D. Lehman-McKeeman and C. D. Klaassen (2013). "Organic anion-transporting polypeptide 1a4 (Oatp1a4) is important for secondary bile acid metabolism." Biochem Pharmacol86(3): 437-445.
Borude, P., G. Edwards, C. Walesky, F. Li, X. Ma, B. Kong, G. L. Guo and U. Apte (2012). "Hepatocyte-specific deletion of farnesoid X receptor delays but does not inhibit liver regeneration after partial hepatectomy in mice." Hepatology 56(6): 2344-2352.
Chavan, H. and P. Krishnamurthy (2012). "Polycyclic aromatic hydrocarbons (PAHs) mediate transcriptional activation of the ATP binding cassette transporter ABCB6 gene via the aryl hydrocarbon receptor (AhR)." J Biol Chem 287(38): 32054-32068.
Cui, J. Y., L. M. Aleksunes, Y. Tanaka, Z. D. Fu, Y. Guo, G. L. Guo, H. Lu, X. B. Zhong and C. D. Klaassen (2012). "Bile acids via FXR initiate the expression of major transporters involved in the enterohepatic circulation of bile acids in newborn mice." Am J Physiol Gastrointest Liver Physiol 302(9): G979-996.
Kong, B., I. L. Csanaky, L. M. Aleksunes, M. Patni, Q. Chen, X. Ma, H. Jaeschke, S. Weir, M. Broward, C. D. Klaassen and G. L. Guo (2012). "Gender-specific reduction of hepatic Mrp2 expression by high-fat diet protects female mice from ANIT toxicity." Toxicol Appl Pharmacol 261(2): 189-195.
Li, F., J. Lu and X. Ma (2012). "CYP3A4-mediated lopinavir bioactivation and its inhibition by ritonavir." Drug Metab Dispos 40(1): 18-24.
Li, H., A. Wolfe, S. Septer, G. Edwards, X. Zhong, A. B. Abdulkarim, S. Ranganathan and U. Apte (2012). "Deregulation of Hippo kinase signalling in human hepatic malignancies." Liver Int 32(1): 38-47.
Polireddy, K., M. M. Khan, H. Chavan, S. Young, X. Ma, A. Waller, M. Garcia, D. Perez, S. Chavez, J. J. Strouse, M. K. Haynes, C. G. Bologa, T. I. Oprea, G. P. Tegos, L. A. Sklar and P. Krishnamurthy (2012). "A novel flow cytometric HTS assay reveals functional modulators of ATP binding cassette transporter ABCB6." PLoS One 7(7): e40005.
Septer, S., G. Edwards, S. Gunewardena, A. Wolfe, H. Li, J. Daniel and U. Apte (2012). "Yes-associated protein is involved in proliferation and differentiation during postnatal liver development." Am J Physiol Gastrointest Liver Physiol 302(5): G493-503.
Zhang, Y., I. L. Csanaky, X. Cheng, L. D. Lehman-McKeeman and C. D. Klaassen (2012). "Organic anion transporting polypeptide 1a1 null mice are sensitive to cholestatic liver injury." Toxicol Sci 127(2): 451-462.
Zhang, Y., J. Y. Hong, C. E. Rockwell, B. L. Copple, H. Jaeschke and C. D. Klaassen (2012). "Effect of bile duct ligation on bile acid composition in mouse serum and liver." Liver Int 32(1): 58-69.
Zhang, Y., P. B. Limaye, L. D. Lehman-McKeeman and C. D. Klaassen (2012). "Dysfunction of organic anion transporting polypeptide 1a1 alters intestinal bacteria and bile acid metabolism in mice." PLoS One 7(4): e34522.
Allen, K., H. Jaeschke and B. L. Copple (2011). "Bile acids induce inflammatory genes in hepatocytes: a novel mechanism of inflammation during obstructive cholestasis." Am J Pathol 178(1): 175-186.
Chavan, H., M. Oruganti and P. Krishnamurthy (2011). "The ATP-binding cassette transporter ABCB6 is induced by arsenic and protects against arsenic cytotoxicity." Toxicol Sci 120(2): 519-528.
Choi, H. J., K. S. Kang, M. Fukui and B. T. Zhu (2011). "Critical role of the JNK-p53-GADD45alpha apoptotic cascade in mediating oxidative cytotoxicity in hippocampal neurons." Br J Pharmacol 162(1): 175-192.
Csanaky, I. L., H. Lu, Y. Zhang, K. Ogura, S. Choudhuri and C. D. Klaassen (2011). "Organic anion-transporting polypeptide 1b2 (Oatp1b2) is important for the hepatic uptake of unconjugated bile acids: Studies in Oatp1b2-null mice." Hepatology 53(1): 272-281.
Flynn, C. A., Y. Alnouti and G. A. Reed (2011). "Quantification of the transporter substrate fexofenadine in cell lysates by liquid chromatography/tandem mass spectrometry." Rapid Commun Mass Spectrom 25(16): 2361-2366.
Fu, X. M., P. Wang and B. T. Zhu (2011). "Characterization of the estradiol-binding site structure of human pancreas-specific protein disulfide isomerase: indispensable role of the hydrogen bond between His278 and the estradiol 3-hydroxyl group." Biochemistry 50(1): 106-115.
Gor, P., Y. Alnouti and G. A. Reed (2011). "Buspirone, fexofenadine, and omeprazole: quantification of probe drugs and their metabolites in human plasma." J Pharm Biomed Anal 55(5): 1127-1135.
Kassel, K. M., A. P. Owens, 3rd, C. E. Rockwell, B. P. Sullivan, R. Wang, O. Tawfik, G. Li, G. L. Guo, N. Mackman and J. P. Luyendyk (2011). "Protease-activated receptor 1 and hematopoietic cell tissue factor are required for hepatic steatosis in mice fed a Western diet." Am J Pathol 179(5): 2278-2289.
Levant, B., T. J. Zarcone, P. F. Davis, M. K. Ozias and S. C. Fowler (2011). "Differences in methylphenidate dose response between periadolescent and adult rats in the familiar arena-novel alcove task." J Pharmacol Exp Ther 337(1): 83-91.
Li, F., J. Lu, L. Wang and X. Ma (2011). "CYP3A-mediated generation of aldehyde and hydrazine in atazanavir metabolism." Drug Metab Dispos 39(3): 394-401.
Li, F., Y. Miao, L. Zhang, S. A. Neuenswander, J. T. Douglas and X. Ma (2011). "Metabolomic analysis reveals novel isoniazid metabolites and hydrazones in human urine." Drug Metab Pharmacokinet 26(6): 569-576.
Li, F., J. Lu and X. Ma (2011). "Metabolomic screening and identification of the bioactivation pathways of ritonavir." Chem Res Toxicol 24(12): 2109-2114.
Li, F., J. Lu and X. Ma (2011). "Profiling the reactive metabolites of xenobiotics using metabolomic technologies." Chem Res Toxicol 24(5): 744-751.
Luyendyk, J. P., K. C. Flanagan, C. D. Williams, H. Jaeschke, J. G. Slusser, N. Mackman and G. H. Cantor (2011). "Tissue factor contributes to neutrophil CD11b expression in alpha-naphthylisothiocyanate-treated mice." Toxicol Appl Pharmacol 250(3): 256-262.
McGill, M. R., H. M. Yan, A. Ramachandran, G. J. Murray, D. E. Rollins and H. Jaeschke (2011). "HepaRG cells: a human model to study mechanisms of acetaminophen hepatotoxicity." Hepatology 53(3): 974-982.
Obaidat, A., J. Weiss, B. Wahlgren, R. R. Manam, V. R. Macherla, K. McArthur, T. H. Chao, M. A. Palladino, G. K. Lloyd, B. C. Potts, S. J. Enna, S. T. Neuteboom and B. Hagenbuch (2011). "Proteasome regulator marizomib (NPI-0052) exhibits prolonged inhibition, attenuated efflux, and greater cytotoxicity than its reversible analogs." J Pharmacol Exp Ther 337(2): 479-486.
Polireddy, K., H. Chavan, B. A. Abdulkarim and P. Krishnamurthy (2011). "Functional significance of the ATP-binding cassette transporter B6 in hepatocellular carcinoma." Mol Oncol 5(5): 410-425.
Roth, M., B. N. Timmermann and B. Hagenbuch (2011). "Interactions of green tea catechins with organic anion-transporting polypeptides." Drug Metab Dispos 39(5): 920-926.
Song, P., Y. Zhang and C. D. Klaassen (2011). "Dose-response of five bile acids on serum and liver bile Acid concentrations and hepatotoxicty in mice." Toxicol Sci 123(2): 359-367.
Williams, C. D., D. J. Antoine, P. J. Shaw, C. Benson, A. Farhood, D. P. Williams, T. D. Kanneganti, B. K. Park and H. Jaeschke (2011). "Role of the Nalp3 inflammasome in acetaminophen-induced sterile inflammation and liver injury." Toxicol Appl Pharmacol 252(3): 289-297.
Wolfe, A., A. Thomas, G. Edwards, R. Jaseja, G. L. Guo and U. Apte (2011). "Increased activation of the Wnt/beta-catenin pathway in spontaneous hepatocellular carcinoma observed in farnesoid X receptor knockout mice." J Pharmacol Exp Ther 338(1): 12-21.
Zhang, Y., I. L. Csanaky, L. D. Lehman-McKeeman and C. D. Klaassen (2011). "Loss of organic anion transporting polypeptide 1a1 increases deoxycholic acid absorption in mice by increasing intestinal permeability." Toxicol Sci 124(2): 251-260.
Zhang, Y. K., G. L. Guo and C. D. Klaassen (2011). "Diurnal variations of mouse plasma and hepatic bile acid concentrations as well as expression of biosynthetic enzymes and transporters." PLoS One 6(2): e16683.
Zhang, E. Y., J. Xiong, B. L. Parker, A. Y. Chen, P. E. Fields, X. Ma, J. Qiu and T. M. Yankee (2011). "Depletion and recovery of lymphoid subsets following morphine administration." Br J Pharmacol 164(7): 1829-1844.
Fukui, M., N. Yamabe, K. S. Kang and B. T. Zhu (2010). "Growth-stimulatory effect of resveratrol in human cancer cells." Mol Carcinog 49(8): 750-759.
Li, F., L. Wang, G. L. Guo and X. Ma (2010). "Metabolism-mediated drug interactions associated with ritonavir-boosted tipranavir in mice." Drug Metab Dispos 38(5): 871-878.
Luyendyk, J. P., B. P. Sullivan, G. L. Guo and R. Wang (2010). "Tissue factor-deficiency and protease activated receptor-1-deficiency reduce inflammation elicited by diet-induced steatohepatitis in mice." Am J Pathol 176(1): 177-186.
Niu, S., F. Li, D. X. Tan, L. Zhang, J. R. Idle, F. J. Gonzalez and X. Ma (2010). "Analysis of N1-acetyl-N2-formyl-5-methoxykynuramine/N1-acetyl-5-methoxy-kynuramine formation from melatonin in mice." J Pineal Res 49(2): 106-114.
Saito, C., J. J. Lemasters and H. Jaeschke (2010). "c-Jun N-terminal kinase modulates oxidant stress and peroxynitrite formation independent of inducible nitric oxide synthase in acetaminophen hepatotoxicity." Toxicol Appl Pharmacol 246(1-2): 8-17.
Saito, C., H. M. Yan, A. Artigues, M. T. Villar, A. Farhood and H. Jaeschke (2010). "Mechanism of protection by metallothionein against acetaminophen hepatotoxicity." Toxicol Appl Pharmacol 242(2): 182-190.
Wang, L., F. Li, J. Lu, G. Li, D. Li, X. B. Zhong, G. L. Guo and X. Ma (2010). "The Chinese herbal medicine Sophora flavescens activates pregnane X receptor." Drug Metab Dispos 38(12): 2226-2231.
Weaver, B. P., Y. Zhang, S. Hiscox, G. L. Guo, U. Apte, K. M. Taylor, C. T. Sheline, L. Wang and G. K. Andrews (2010). "Zip4 (Slc39a4) expression is activated in hepatocellular carcinomas and functions to repress apoptosis, enhance cell cycle and increase migration." PLoS One 5(10).
Weaver, Y. M., D. J. Ehresman, J. L. Butenhoff and B. Hagenbuch (2010). "Roles of rat renal organic anion transporters in transporting perfluorinated carboxylates with different chain lengths." Toxicol Sci 113(2): 305-314.
Williams, C. D., M. L. Bajt, A. Farhood and H. Jaeschke (2010). "Acetaminophen-induced hepatic neutrophil accumulation and inflammatory liver injury in CD18-deficient mice." Liver Int 30(9): 1280-1292.
Williams, C. D., A. Farhood and H. Jaeschke (2010). "Role of caspase-1 and interleukin-1beta in acetaminophen-induced hepatic inflammation and liver injury." Toxicol Appl Pharmacol 247(3): 169-178.
Zhang, Y. and C. D. Klaassen (2010). "Effects of feeding bile acids and a bile acid sequestrant on hepatic bile acid composition in mice." J Lipid Res 51(11): 3230-3242.
Baker, A. K., R. Wang, N. Mackman and J. P. Luyendyk (2009). "Rapamycin enhances LPS induction of tissue factor and tumor necrosis factor-alpha expression in macrophages by reducing IL-10 expression." Mol Immunol 46(11-12): 2249-2255.
Luyendyk, J. P., G. H. Cantor, D. Kirchhofer, N. Mackman, B. L. Copple and R. Wang (2009). "Tissue factor-dependent coagulation contributes to alpha-naphthylisothiocyanate-induced cholestatic liver injury in mice." Am J Physiol Gastrointest Liver Physiol 296(4): G840-849.
Zhu, B. T., P. Wang, M. Nagai, Y. Wen and H. W. Bai (2009). "Inhibition of human catechol-O-methyltransferase (COMT)-mediated O-methylation of catechol estrogens by major polyphenolic components present in coffee." J Steroid Biochem Mol Biol 113(1-2): 65-74.
Bai, H. W. and B. T. Zhu (2008). "Strong activation of cyclooxygenase I and II catalytic activity by dietary bioflavonoids." J Lipid Res 49(12): 2557-2570.
Reed, G. A., J. M. Sunega, D. K. Sullivan, J. C. Gray, M. S. Mayo, J. A. Crowell and A. Hurwitz (2008). "Single-dose pharmacokinetics and tolerability of absorption-enhanced 3,3'-diindolylmethane in healthy subjects." Cancer Epidemiol Biomarkers Prev 17(10): 2619-2624.
Zhu, B. T. (2008). "Is it necessary to control the level of estrogen receptor alpha and beta activation in postmenopausal hormone replacement therapy in order to achieve the optimal outcome? (Review)." Mol Med Rep 1(1): 15-20.
Alnouti, Y. M., M. K. Shelby, C. Chen and C. D. Klaassen (2007). "Influence of phenobarbital on morphine metabolism and disposition: LC-MS/MS determination of morphine (M) and morphine-3-glucuronide (M3G) in Wistar-Kyoto rat serum, bile, and urine." Curr Drug Metab 8(1): 79-89.
Chen, A. Y., A. J. Lee, X. R. Jiang and B. T. Zhu (2007). "Chemical synthesis of six novel 17beta-estradiol and estrone dimers and study of their formation catalyzed by human cytochrome P450 isoforms." J Med Chem 50(22): 5372-5381.
Dai, G., L. He, N. Chou and Y. J. Wan (2006). "Acetaminophen metabolism does not contribute to gender difference in its hepatotoxicity in mouse." Toxicol Sci 92(1): 33-41.
Reed, G. A., D. W. Arneson, W. C. Putnam, H. J. Smith, J. C. Gray, D. K. Sullivan, M. S. Mayo, J. A. Crowell and A. Hurwitz (2006). "Single-dose and multiple-dose administration of indole-3-carbinol to women: pharmacokinetics based on 3,3'-diindolylmethane." Cancer Epidemiol Biomarkers Prev 15(12): 2477-2481.