Clinical Research

Research Team

KU OTOLARYNGOLOGY CLINICAL RESEARCH LEADS: Dr. Kevin Sykes, PhD, MPH and Bryan Humphrey, RRT-NPS

The Department of Otolaryngology's commitment of resources to clinical and basic science research promises to keep the University of Kansas at the forefront of advancement for the specialty.  The department conducts ongoing, critical review of the care we provide to our patients. Retrospective studies, including multicenter projects, serve to analyze the patterns and outcomes for patients with the aim of improving the evidence base for our treatment options and generating hypotheses for future research. Utilizing large national administrative datasets allows for health services research that examines similar questions on a national scale looking for trends and opportunities for improvements in care related to otolaryngology as it is performed in the United States.

We provide our patients access to the most advanced therapies available by supporting clinical research. Kevin Sykes, PhD, MPH leads this division of the department as the Director of Clinical Research and has been in this role since 2005. This is a team effort and critical to our success is the experience and effort of our Clinical Research Coordinator, Bryan Humphrey, RRT-NPS. Since 2010, we have offered full-time or part-time research assistant positions for students interested in medical school. In 2016, we began a Research Fellowship, currently held by Chelsea Hamill, MD, that provides recent medical school graduates with a year of research experience.

As one of the leading neurotology sites in the United States for hearing and balance related research and clinical trials, we attract patients from across the country interested in advancing science and receiving care that is only offered at select institutions. This research includes a first of its kind Phase I clinical trial testing the safety and tolerability of an inner ear infusion of CGF166, a gene therapy aiming to treat severe to profound hearing loss. We also routinely offer clinical trials in head and neck oncology, pediatric otolaryngology, and rhinology. We are currently enrolling in the clinical trials listed below, and one of our clinical research team members would be happy to help you learn more about these trials.

To register as a clinical trial volunteer, go to the KUMC website for volunteers.

To confirm your eligibility to participate in a clinical trial, contact our clinical research office by emailing entresearch@kumc.edu or by dialing (913) 588-3759. 

 

 Active Clinical Research Trials in the Department of Otolaryngology-Head and Neck Surgery


Otology

A three-part, multicenter, open label, single dose study to assess the safety, tolerability, and efficacy of intra-labyrinthine (IL) CGF166 in patients with severe hearing loss.
Principal Investigator: Hinrich Staecker, MD, PhD  

Long-term Safety and Efficacy Follow-up Study of CGF166-Treated Patients                
Principal Investigator: Hinrich Staecker, MD, PhD 

The HEARRING Registry, Quality of Life Assessment, and Genetic Sub-Studies - A Collaborative Effort for Global Outcomes with MED-EL Hearing Implants
Principal Investigator: Hinrich Staecker, MD, PhD   

Efficacy and Safety of AM-III as Acute Sudden Sensorineural Hearing Loss Treatment (ASSENT)
Principal Investigator: Hinrich Staecker, MD, PhD   

Electric-Acoustic Stimulation Extended Follow-up Post-Approval Study
Principal Investigator: Hinrich Staecker, MD, PhD   


General Otolaryngology

Prospective, Non-Randomized Registry for the Evaluation of Sialendoscopy in the Diagnosis and Management of Sialolithiasis and Chronic Sialadenitis
Principal Investigator: Christopher Larsen, MD  

PROSPECTIVE Monitoring Juvenile Onset Recurrent Respiratory Papillomatosis - A Multicenter CDC Sponsored Registry                
Principal Investigator: Daniel Bruegger, MD  

RETROSPECTIVE Monitoring Juvenile Onset Recurrent Respiratory Papillomatosis - A Multicenter CDC Sponsored Registry                
Principal Investigator: Daniel Bruegger, MD  

AAO-HNS Simulation as a Tool for Education Innovation: The Simtube Project                
Principal Investigator: Keith Sale, MD    


Head and Neck Oncology

Patient Education and Satisfaction in Free Flap Surgery                
Principal Investigator: Kiran Kakarala, MD

Last modified: Jul 11, 2017
ID=x6129