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Neurobiology Research Laboratory

The Neurobiology Research Laboratory (NBRL) of the Departments of Neurology and Pharmacology (Toxicology and Therapeutics), University of Kansas Medical Center (KUMC), was established at the Kansas City Veterans Affairs Medical Center, now part of the Heartland Veterans Integrated Service Network (VISN15), in 1976. Barry W. Festoff, M.D., the founding Director, NBRL, is Professor of Neurology and Pharmacology, KUMC. For almost thirty years, the NBRL has pursued approaches equally divided between clinical neurology and neurobiology in a research and academic environment. The guiding theme, or thread, of the research studies of the NBRL is that development, plasticity after injury, and disease of the nervous system all involve similar mechanisms in a relatively simple repertoire of means with which this system can react.

Spinal Cord Injury (SCI)

Recent estimates are that in the United States alone approximately 400,000 people live with some form of SCI or disorder that significantly affects their life activities. About 12,000 more sustain these injuries each year. Spinal cord injury result in loss of motor function which is associated with secondary cell death of neurons. Motor neurons undergo a programmed cell death termed apoptosis which peaks within three days after the injury. Our goal is to find a way to inhibit this cell death process and enable to improve post-injury recovery.

Last modified: Sep 28, 2018
Our location

Kansas City VA Medical Center
4801 Linwood Blvd.
Kansas City, MO 64128-2295

Located in the Research Wing

Room 208A: Administrative Office

2nd floor: Offices, Main Laboratories

4th, 5th floors: Laboratories

Subbasement: In situ facilities


mri of contusion spinal cord injury
MRI image of contusion Spinal Cord injury in mouse. Sagittal view with an arrow pointing to T10 laminectomy and cord lesion. [courtesy: Dr. Bilgen]