Andrei B. Belousov, Ph.D.

Associate Professor
Moscow State University, Russia, 1992


Research Focus

Patch-clamp electrophysiology, calcium digital imaging, immunocytochemistry, multiple molecular biology techniques, confocal microscopy, primary cell cultures, acute brain slices, transgenic animals.

Research Focus

Patch-clamp electrophysiology, calcium digital imaging, immunocytochemistry, multiple molecular biology techniques, confocal microscopy, primary cell cultures, acute brain slices, transgenic animals.

Research Interests

We are interested in the mechanisms of regulation of neuronal gap junctions (electrical synapses) during development and neuronal injury. We also study the role of neuronal gap junctions in death of neurons in the developing nervous system and in the secondary, glutamate-dependent neuronal death following ischemic stroke, traumatic brain injury and epilepsy. As a result of these studies, a novel model of the mechanisms of glutamate-dependent neuronal death has been proposed, where neuronal gap junctions play a critical role.

Selected Publications

Arumugam H., Liu X., Colombo P.J., Corriveau R.A., Belousov A.B. NMDA receptors regulate developmental gap junction uncoupling via CREB signaling. Nature Neuroscience, 8 (12): 1720-1726, 2005. Abstract.
NEWS AND VIEWS: Nature Neuroscience, 8 (12): 1633-1634, 2005. Abstract.
IN THE NEWS: Nature Reviews Neuroscience, 7 (1): 8-9, 2006. Abstract.

deRivero Vaccari J.C., Corriveau R.A., Belousov A.B. Gap junctions are required for NMDA receptor-dependent cell death in developing neurons. Journal of Neurophysiology, 98 (5): 2878-2886, 2007. Abstract.

Wang Y., Denisova J.V., Kang K.S., Fontes J.D., Zhu B.T., Belousov A.B. Neuronal gap junctions are required for NMDA receptor-mediated excitotoxicity: implications in ischemic stroke. Journal of Neurophysiology, 104 (6): 3551-3556, 2010. Abstract.

Park W.-M., Wang Y., Park S., Denisova J.V., Fontes J.D., Belousov A.B. Interplay of chemical neurotransmitters regulates developmental increase in electrical synapses. The Journal of Neuroscience, 31 (16): 5909-5920, 2011. Abstract.

THIS WEEK IN THE JOURNAL: The Journal of Neuroscience, 31(16): i-i, 2011. Abstract.

Belousov A.B. The regulation and role of neuronal gap junctions during development. Communicative & Integrative Biology, 4 (5): 579-581, 2011. Abstract.

Wang Y., Song J.-H., Denisova J.V., Park W.-M., Fontes J.D., Belousov A.B. Neuronal gap junction coupling is regulated by glutamate and plays critical role in cell death during neuronal injury. The Journal of Neuroscience, 32 (2): 713-725, 2012. Abstract.
THIS WEEK IN THE JOURNAL: The Journal of Neuroscience, 32 (2): i, 2012. Abstract.

Belousov A.B. The regulation and role of neuronal gap junctions during neuronal injury. Channels, 6 (5): 390-392, 2012. Abstract.

Belousov A.B., Wang Y., Song J.-H., Denisova J.V., Berman N.E., Fontes J.D. Neuronal gap junctions play a role in the secondary neuronal death following controlled cortical impact. Neuroscience Letters, 524 (1): 16-19, 2012. Abstract.  

Last modified: Oct 07, 2014

Contact

Andrei B. Belousov, Ph.D.
Associate Professor

2095 HLSIC
3901 Rainbow Blvd.
Kansas City, KS 66160

P: 913-588-9968
F: 913-588-5677
abelousov@kumc.edu

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