MICR801 Syllabus

Principles of Immunology (MICR 801) -  Fall, 2013

A.         Course objectives:

 1.              To apply an understanding of the cellular and molecular basis for an immune response to a variety of biomedical research problems

2.              To understand the nature of immune cell differentiation and activation by foreign antigens or patterns and the mechanisms of immune effector functions

3.              To be able to identify immune-based diseases and the general pathogenesis of prototype immunological diseases

4.              To appreciate experimental approaches to studying basic and applied immunology and the health-related contexts of the immune system

 

B.         Schedule of Sessions

9:00 - 10:30 AM, Tuesdays and Thursdays, except where noted below

Room 1007 Orr-Major

We follow the principles of the flipped classroom in this course.  Please read the recommended material prior to class.

  

Day, Date

Instructor

Topic

Kuby Text *

1

Tues, Aug 27

Parmely

Immune system overview

Ch 1,2

2

Thurs, Aug 29

Parmely

Innate immunity and inflammation

Ch 3

3

Tues, Sept 3

Parmely

Antigen recognition

Ch 4,5,6

4

Thurs, Sept 5

Parmely

T cells, MHC and immune repertoires

Ch 8,9

5

Tues, Sept 10, 10:30 AM

Parmely

Lymphocyte development and activation

Ch 10,11,12

6

Thurs, Sept 12

Parmely

Immune effector mechanisms

Ch 7,13,14

7

Tues, Sept 17

Parmely

Immune tissue injury

Ch 15

8

Wed, Sept 19 

Parmely

Immune tolerance and autoimmunity

Ch 16

9

Thurs, Sept 24

Parmely

Transplantation immunology

Ch 17

10

Tues, Sept 26

Parmely

Immune responses to microbes

Ch 18,19 

11

Tues, Oct 1

Parmely

Experimental applications

Ch 22

 

Mon, Oct 7, 5 PM

--

Final written assignment due

 

* You should occasionally consult chapter 22 for experimental approaches that might be applicable to your readings.

  

C.              Evaluation

                  30% classroom participation/assignments/readiness quizzes

                  30% mid-course written assignment

                  40% final written assignment

                  Grading Scale:                     86 - 100% = A                       71 - 85% = B                          70 or below = C

  

  

  

  

D.        Instructor            

 

                  Michael Parmely                                                                    

                  3003 Hixon, mparmely@kumc.edu                                            

                  Tel: 8-7053         

 

E.         Required textbook

Kindt TJ, RA Goldsby, BA Osborne, Kuby Immunology, 6th edition, WH Freeman, New York, 2007

  

F.         Classroom sessions

 

We will not have formal lectures (unless you students want to give them).  Rather, I would ask that you simply prepare a list of 5-6 overarching principles that you derived from the readings assigned for that day.  For example, after reading the first chapter, you might find that a definition of immunity would be a good general principle.

 

I will also provide you with a list of discussion points prior to each class meeting, so that you can begin to consider the significance of your readings as you are going through them.  When we meet, we will go through these points, answer questions you might have and consider some of the ways in which immunologists experimentally study the material addressed by the readings.

 

You should always be prepared for a "readiness quiz," an exercise that may count towards your grade that tests your preparation for discussing the material assigned that day. 

 

G.             Angel Learning Site

 

A site for the course will be established on Blackboard.  Once you have been registered as a student for this site, you will be able to find general class announcements and materials.  You will also be dropping assignments in a drop box on Blackboard as these become due.  

 

H.             Our First Meeting

 

As you may have noticed by the schedule, you have a reading assignment for our first meeting, which is already posted on the Blackboard course site.  This includes relevant discussion points we will review during this session.  Call or drop me an email if you cannot access the material on Blackboard.

Last modified: Aug 15, 2013
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