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MICR801 Syllabus

REVISED Principles of Immunology (MICR 801) -  Fall, 2012

A.         Course objectives:

1.              To appreciate the cellular and molecular basis for an immune response to foreign substances

2.              To understand the nature of immune cell differentiation and activation by foreign antigens or patterns and the mechanisms of immune effector functions

3.              To be able to identify immune-based diseases and the general pathogenesis of prototype immunological diseases

4.              To appreciate experimental approaches to studying basic and applied immunology and the health-related contexts of the immune system

  

B.         Schedule of Sessions

9:00 - 10:30 AM, Tuesdays and Thursdays, except where noted below

Room 1007 Orr-Major

Please read the recommended material prior to class.

REVISED SCHEDULE

  

Day, Date

Instructor

Topic

Kuby Text *

1

Tues, Aug 21

Parmely

Immune system overview

Ch 1,2

2

Thurs, Aug 23

Parmely

Innate immunity and inflammation

Ch 3

3

Tues, Aug 28

Parmely

Antigen recognition

Ch 4,5,6

4

Thurs, Aug 30

Parmely

T cells, MHC and immune repertoires

Ch 8,9

5

Tues, Sept 4

Parmely

Lymphocyte development and activation

Ch 10,11,12

6

Thurs, Sept 6

Parmely

Immune effector mechanisms

Ch 7,13,14

7

Tues, Sept 11

Parmely

Immune tissue injury

Ch 15

8

Wed, Sept 12 1 PM

Parmely

Immune tolerance and autoimmunity

Ch 16

9

Thurs, Sept 13

Parmely

Immune responses to microbes

Ch 18,19

10

Tues, Sept 18

Karan

Transplantation immunology

Ch 17 

11

Thurs, Sept 27

--

Final written assignment due

 

                  * You should occasionally consult chapter 22 for experimental approaches that might be applicable to                  your readings.

  

C.              Evaluation

                  30% classroom participation/assignments/readiness quizzes

                  30% mid-course written assignment

                  40% final written assignment

                  Grading Scale:                     86 - 100% = A                       71 - 85% = B                          70 or below = C

  

D.        Instructors         

 

                  Michael Parmely                                                                                       Dev Karan

                  3003 Hixon, mparmely@kumc.edu                                              dkaran@kumc.edu

                  Tel: 8-7053                                                                                                    Tel: 5-6670

E.         Required textbook

Kindt TJ, RA Goldsby, BA Osborne, Kuby Immunology, 6th edition, WH Freeman, New York, 2007

  

  

F.         Classroom sessions

 

We will not have formal lectures (unless you students want to give them).  Rather, I would ask that you simply prepare a list of 5-6 overarching principles that you derived from the readings assigned for that day.  For example, after reading the first chapter, you might find that a definition of immunity would be a good general principle.

 

I will also provide you with a list of discussion points prior to each class meeting, so that you can begin to consider the significance of your readings as you are going through them.  When we meet, we will go through these points, answer questions you might have and consider some of the ways in which immunologists experimentally study the material addressed by the readings.

 

You should always be prepared for a "readiness quiz," an exercise that can count towards your grade that tests your preparation for discussing the material assigned that day. 

 

G.             Angel Learning Site

 

A site for the course will be established on Angel.  Once you have been registered as a student for this site, you will be able to find general class announcements and materials.  You will also be dropping assignments in a drop box on Angel as these become due.  

 

H.             Our First Meeting

 

As you may have noticed by the schedule, you have a reading assignment for our first meeting, which is already posted on the Angel course site.  This includes relevant discussion points we will review during this session.  Call or drop me an email if you cannot access the material on Angel.


     Last modified: Aug 22, 2012