REVISED Principles of Immunology (MICR 801) - Fall, 2012
A. Course objectives:
1. To appreciate the cellular and molecular basis for an immune response to foreign substances
2. To understand the nature of immune cell differentiation and activation by foreign antigens or patterns and the mechanisms of immune effector functions
3. To be able to identify immune-based diseases and the general pathogenesis of prototype immunological diseases
4. To appreciate experimental approaches to studying basic and applied immunology and the health-related contexts of the immune system
B. Schedule of Sessions
9:00 - 10:30 AM, Tuesdays and Thursdays, except where noted below
Room 1007 Orr-Major
Please read the recommended material prior to class.
REVISED SCHEDULE
|
|
Day, Date |
Instructor |
Topic |
Kuby Text * |
|
1 |
Tues, Aug 21 |
Parmely |
Immune system overview |
Ch 1,2 |
|
2 |
Thurs, Aug 23 |
Parmely |
Innate immunity and inflammation |
Ch 3 |
|
3 |
Tues, Aug 28 |
Parmely |
Antigen recognition |
Ch 4,5,6 |
|
4 |
Thurs, Aug 30 |
Parmely |
T cells, MHC and immune repertoires |
Ch 8,9 |
|
5 |
Tues, Sept 4 |
Parmely |
Lymphocyte development and activation |
Ch 10,11,12 |
|
6 |
Thurs, Sept 6 |
Parmely |
Immune effector mechanisms |
Ch 7,13,14 |
|
7 |
Tues, Sept 11 |
Parmely |
Immune tissue injury |
Ch 15 |
|
8 |
Wed, Sept 12 1 PM |
Parmely |
Immune tolerance and autoimmunity |
Ch 16 |
|
9 |
Thurs, Sept 13 |
Parmely |
Immune responses to microbes |
Ch 18,19 |
|
10 |
Tues, Sept 18 |
Karan |
Transplantation immunology |
Ch 17 |
|
11 |
Thurs, Sept 27 |
-- |
Final written assignment due |
|
* You should occasionally consult chapter 22 for experimental approaches that might be applicable to your readings.
C. Evaluation
30% classroom participation/assignments/readiness quizzes
30% mid-course written assignment
40% final written assignment
Grading Scale: 86 - 100% = A 71 - 85% = B 70 or below = C
D. Instructors
Michael Parmely Dev Karan
3003 Hixon, mparmely@kumc.edu dkaran@kumc.edu
Tel: 8-7053 Tel: 5-6670
E. Required textbook
Kindt TJ, RA Goldsby, BA Osborne, Kuby Immunology, 6th edition, WH Freeman, New York, 2007
F. Classroom sessions
We will not have formal lectures (unless you students want to give them). Rather, I would ask that you simply prepare a list of 5-6 overarching principles that you derived from the readings assigned for that day. For example, after reading the first chapter, you might find that a definition of immunity would be a good general principle.
I will also provide you with a list of discussion points prior to each class meeting, so that you can begin to consider the significance of your readings as you are going through them. When we meet, we will go through these points, answer questions you might have and consider some of the ways in which immunologists experimentally study the material addressed by the readings.
You should always be prepared for a "readiness quiz," an exercise that can count towards your grade that tests your preparation for discussing the material assigned that day.
G. Angel Learning Site
A site for the course will be established on Angel. Once you have been registered as a student for this site, you will be able to find general class announcements and materials. You will also be dropping assignments in a drop box on Angel as these become due.
H. Our First Meeting
As you may have noticed by the schedule, you have a reading assignment for our first meeting, which is already posted on the Angel course site. This includes relevant discussion points we will review during this session. Call or drop me an email if you cannot access the material on Angel.