Participating in the PKD Biomarkers study will help researchers discover new biomarkers that:
Monitor early changes in the kidneys as cysts begin to grow and cause damage.
Monitor the effectiveness of new drugs being developed for PKD.
Finding new biomarkers are important as new therapies are being developed and tested.
Who can Participate
Children age 4 years and above
Adults age 18 to 35
Diagnosed with PKD
Sibling of diagnosed study participants may also enroll if they have been screened and do not have kidney cysts
Able to have an MRI if age 7 years or older
Able to come to study visits yearly for the next 5 years in either Kansas City or Chicago
What do you have to do?
Provide medical history, have blood pressure, weight, and height measured
If previously diagnosed with PKD, participants age 7 and above will have an MRI of the kidneys every other year
Blood and urine will be collected at each visit
Study visits will require 1 hour (without MRI) and up to 2 hours (if visit includes an MRI) and must be done while the participant is fasting
Is there compensation?
There is no cost for being in the study or for the MRI
Subjects will receive $50 per visit
Travel reimbursement and hotel lodging is provided for participants who live more than 50 miles away from Kansas City
Video
Learn more about why we are doing this research and what it means for you.
Site Directors
Kansas Site Director Darren P. Wallace, Ph.D. Professor and PKD Center Associate Director Tel. 913-588-3889 (office) Tel. 913-588-3811 (lab) e-mail: dwallace@kumc.edu
Missouri Site Director Laurel Willig, MD Pediatric Nephrologist Associate Professor of Pediatrics University of Missouri-Kansas City School of Medicine Children's Mercy Hospital 2401 Gillham Rd Kansas City, MO 6410 Tel. 816-234-3030
Chicago Site Director Arlene Chapman, MD Professor of Medicine Director, Section of Nephrology Department of Medicine Director, Clinical Research Center Institute for Translational Medicine Biological Sciences Division University of Chicago e-mail: Achapman1@medicine.bsd.uchicago.edu Tel. 773-702-8055 Fax: 773-702-5818 eFax: 773-753-8301
How Can I Participate? Contact the Study Coordinators to learn more:
University of Kansas Medical Center Study Coordinators Cathy Creed, RN Tel. 913-588-0053 Fax: 913-588-8986 e-mail: ccreed@kumc.edu
