Jared J. Grantham Symposium

"The Future of Polycystic Kidney Disease Research"

Wednesday, May 7th - Friday, May 9th, 2014
InterContinental Hotel on the Plaza, Kansas City, MO

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To honor Dr. Jared Grantham in his retirement, the Kidney Institute at the University of Kansas Medical Center will host the first Jared J. Grantham Symposium on May 7 - 9th, 2014 in Kansas City. Dr. Grantham's vision was to invite all of the Lillian Jean Kaplan award recipients to lead a forward-thinking and interactive forum that will focus on future directions and innovations in polycystic kidney disease research. We hope that you will join us in Kansas City to share your ideas with colleagues, develop new collaborations, and help shape the future of polycystic kidney disease research. We expect that this will be a unique experience for all.

The symposium's presentations and panels will be centered around three themes:

Session I : Thursday, May 8th - 8:30am - 11:45am
The Role of Polycystins and Associated Proteins
Moderator: Dr. Stephen Reeders

  • Dr. James Calvet - "Neoplastic cyst growth in PKD: Maybe so, but where's the cancer?"
  • Dr. Peter Harris - "ADPKD mutations, polycystin processing and interdependence help understand pathogenesis"
  • Dr. Stefan Somlo - "Knowing what we don't know: Polycystin function in cilia"
  • Dr. Greg Germino - "Pathogenic mechanisms in PKD: Are we finally coming out of the woods?

Session II: Thursday, May 8th - 1:15pm - 4:30pm
Disease Pathogenesis and the Role of Cilia
Moderator: Dr. Alan Yu

  • Dr. Dorien Peters - "Molecular Pathogenesis of Polycystic Kidney Disease: What can we learn from mice?"
  • Dr. Friedhelm Hildebrandt - "DNA damage response signaling in ciliopathies"
  • Dr. Jing Zhou - "PKD and cilia: What are the cilia actually doing?
  • Dr. Corinne Antignac - "Nephronophthisis and associated extra-renal ciliopathies: Insights into genetics and pathogenesis"

Session III: Friday, May 9th - 8:30am - 11:45am
Animal Models, Biomarkers and Therapies
Moderator: Dr. Ben Cowley

  • Dr. Gerd Walz - "Novel mTOR-based strategies to block cyst growth"
  • Dr. Lisa Guay-Woodford - "Genetic modifiers in recessive polycystic kidney disease: can mice teach us about human disease?" 
  • Dr. Vicente Torres - "What are next-generation PKD therapies going to target in the kidney?"
  • Dr. Jared Grantham - "Thinking about urine-and a treatment for polycystic kidney disease"

Keynote Dinner Lecture: Thursday, May 8, 7:00-8:30pm
"Pediatric Genomic Medicine"
Dr. Stephen Kingsmore

Director, Center for Pediatric Genomic Medicine
Children's Mercy Hospital

Stephen F. Kingsmore was appointed Director of the Children's Mercy Center for Pediatric Genomic Medicine in January 2011. He was named one of the best physicians of 2012 by Medscape. Previously, Dr. Kingsmore was variously the President, CEO and Chief Scientific Officer of the National Center for Genome Resources, Santa Fe, New Mexico. Prior to this, Dr. Kingsmore was Chief Operating Officer of Molecular Staging Inc., Vice President of Research of CuraGen Corp. and Assistant Professor at the University of Florida. Dr. Kingsmore received a B.Sc. in medical microbiology, degrees in medicine (M.B., Ch.B., B.A.O.) and D.Sc. in molecular genetics from the Queen's University Belfast in Northern Ireland. He completed residency in Internal Medicine and fellowship in Rheumatology at Duke. He is a Fellow of the Royal College of Pathologists (UK) and a member of the DHHS Secretary's Advisory Committee on Heritable Disorders in Newborns and Children Carrier Screening Workgroup. His research interests are genome analysis, systems surveys and individualized medicine.

Symposium Format

The format of the symposium will include a combination of didactic presentations and interactive panel discussions. Each session will feature a series of 30-minute presentations by the Kaplan awardees on a topic related to the session's central theme. Following the lectures, a moderated panel discussion will wrap up each session with lively debate focused on key questions related to the central theme. We encourage attendees to suggest key questions and discussion topics during the registration process.

In addition to the conference sessions, we hope that you'll attend the dinner keynote presentations on Wednesday and Thursday evenings in the Rooftop Ballroom at the InterContinental Hotel. Our keynote lecturers will provide unique insights into the novelties, challenges and future direction of PKD research.  The symposium registration fee includes both keynote dinners on Wednesday and Thursday evenings, in addition to all meals and snacks on Thursday and Friday.


We greatly appreciate the support of our sponsors and donors. 

If you are interested in making a donation to support the Grantham Symposium, please contact:

Lyn Harris
Administrative Director
Kidney Institute
University of Kansas Medical Center
Tel. 913.588.6075
E-mail: lharris3@kumc.edu

Last modified: May 16, 2014