Robin Maser

Clinical Laboratory Sciences – Assistant Professor
Kidney Institute – Faculty
Department of Clinical Laboratory Sciences

B.A., William Jewell College, Liberty, MO, 1980
Graduate Fellowship, National Science Foundation, 1984-87
Ph.D., University of Kansas Medical Center, Kansas City, KS, 1989
Postdoctoral Fellow, Department of Biochemistry and Molecular Biology, University of Kansas Medical Center, Kansas City, KS, 1989-93
Research Associate, Biochemistry and Molecular Biology, University of Kansas Medical Center, Kansas City, KS, 1993-1995


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Research Focus

My research interests revolve around the pathogenesis and treatment of polycystic kidney disease (PKD). In particular, my lab has focused on the structure-function relationships of polycystin-1 (PC-1), the protein product of the PKD1 gene, and the contribution of reduced antioxidant protection to the pathogenetic mechanism of PKD. These interests have resulted in five main research projects: the mechanism of membrane insertion of polycystin-1 and how this contributes to polycystin-1 cellular localization and signaling functions; the mechanism of polycystin-1 mediated antioxidant response element (ARE) gene expression; the regulation of ARE genes by fluid shear stress in renal epithelial cells; the contribution of oxidant stress to the pathogenic mechanism of PKD; and the potential effect of antioxidant-based therapies for amelioration of PKD severity

Last modified: May 02, 2013

R Maser

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Robin Maser
Clinical Laboratory Sciences – Assistant Professor
Kidney Institute – Faculty

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