The Center for Epigenetics and Stem Cell Biology

stem cell

Director: Kenneth R. Peterson, Ph.D., Vice Chair of Biochemistry and Molecular Biology

Members of the Center for Epigenetics and Stem Cell Biology investigate how cells become specialized in their function. This process is referred to as cell differentiation. Cell differentiation is a hallmark of embryogenesis. During embryonic development, cells increase in number, become specialized, and organize into tissues. Some examples of cell specialization include the formation of red blood cells, which transport oxygen; muscle cells, which produce movement; and neurons, which allow us to reason. The developmental fate of an undifferentiated cell, also referred to as a stem cell, is dictated by the cell's genetic program and its interactions with its environment. Acquisition of a specific cell fate is associated with the systematic modulation of regulatory processes controlling the function of genes and proteins. Abnormalities in cell differentiation cause birth defects and lead to adult disease. Understanding molecular mechanisms controlling cell differentiation will result in the development of new strategies for the treatment of disease. These approaches will include the generation of unique drug- and cell-based therapies. The applications of these new therapeutic tools will be numerous and include potential treatments for infertility and a diverse range of debilitative diseases, such as, cancer, diabetes, liver fibrosis, stroke, heart disease, vascular and blood diseases, Alzheimer's and Parkinson's diseases, and spinal cord injury, in addition to many others.

Members 

Aljitawi, Omar

Apte, Udayan

Behbod, Fariba

Blumenstiel, Justin

Bortolato, Marco

Butler, Merlin

Cheng, Nikki

Damjanov, Ivan

Dawn, Buddhadeb

Detamore, Michael

Dhar, Animesh

DiTacchio, Luciano

Fields, Patrick

Fields, Tim

Fontes, Joseph

Iwakuma, Tomoo

Johnson, Rajasingh

 Krieg, Adam

 Lampe, Jed

 Lewis-Wambi, Joan

Li, Benyi

Li, Xiaogang

 Macdonald, Stuart

 Manzardo, Ann

 Paul, Arghya

 Paul, Arindam

 Paul, Soumen

Peterson, Kenneth

 Rumi, Mohammad

Saadi, Irfan 

Slawson, Chad

Swenson-Fields, Katherine

Swerdlow, Russell

Vivian, Jay

Wang, Jinxi

Weiss, Mark

Yankee, Thomas

Yu, Alan

 Zhu, Hao

 


 

Last modified: Nov 26, 2014
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