Department of Mechanical Engineering - Kansas University School of Engineering
Ph.D., Duke University, 2005
Dr. Kieweg is an Assistant Professor in Mechanical Engineering, at the Lawrence campus of the University of Kansas. She has held a courtesy position in Obstetrics & Gynecology at the KU School of Medicine since 2007. Dr. Kieweg conducts research in non-Newtonian fluid mechanics with applications in biomechanics, primarily to improve the drug delivery of anti-HIV microbicides. Her research also has applications in women's health including instrument design, soft tissue mechanics of the female pelvic floor, and the biomechanics of delivery.
Dr. Kieweg was an NIH K12 Building Interdisciplinary Research Careers in Women's Health (BIRCWH) Scholar (2007 - 2011) at KUMC and is the PI of a 5-year NIH phased R21/R33 award, funded through the NIH Microbicide Innovation Program. As co-PI on a Major Research Instrumentation grant from the National Science Foundation, she is conducting high performance computational simulations of thin film flow of non-Newtonian fluids to enable the rational design of microbicide delivery vehicles. Other projects include the development of mathematical models of relevant transport phenomena to design nanomedicines for microbicide drug delivery. Additional funding includes a Kauffman Foundation/Institute for Advancing Medical Innovation proof-of-concept award for a device that will automatically vitrify reproductive cells and tissue to preserve fertility in cancer patients. Her IRHRM collaborators include Dr. David Albertini, Dr. S. Samuel Kim, and Dr. Carl Weiner.
Singh V, Misra A, Marangos O, Park J, Ye Q, Kieweg SL, Spencer P. Viscoelastic and fatigue properties of model methacrylate-based dentin adhesives. J Biomed Mater Res B Appl Biomater. 2010 Nov;95(2):283-90.
Muffly TM, Boyce J, Kieweg SL, Bonham AJ. Tensile strength of a surgeon's or a square knot. J Surg Educ. 2010 Jul-Aug;67(4):222-6.
Park J, Ye Q, Topp EM, Misra A, Kieweg SL, Spencer P. Effect of photoinitiator system and water content on dynamic mechanical properties of a light-cured bisGMA/HEMA dental resin. J Biomed Mater Res A. 2010 Jun 15;93(4):1245-51.
Kieweg SL, Katz DF. Interpreting properties of microbicide drug delivery gels: analyzing deployment kinetics due to squeezing. J Pharm Sci. 2007 Apr;96(4):835-50.
Owen DH, Peters JJ, Kieweg SL, Geonnotti AR, Schnaare RL, Katz DF. Biophysical analysis of prototype microbicidal gels. J Pharm Sci. 2007 Mar;96(3):661-9.
Kieweg SL, Katz DF. Squeezing flows of vaginal gel formulations relevant to microbicide drug delivery. J Biomech Eng. 2006 Aug;128(4):540-53.
Kieweg SL, Geonnotti AR, Katz DF. Gravity-induced coating flows of vaginal gel formulations: in vitro experimental analysis. J Pharm Sci. 2004 Dec;93(12):2941-52.
Sarah L. Kieweg, Ph.D.