M.A. Karim Rumi, M.B.B.S., M.S., Ph.D.

Research Associate Professor
Dept. of Pathology and Laboratory Medicine
Member, Center for Epigenetics and Stem Cell Biology

M.B.B.S., Dhaka Medical College, Dhaka University, Bangladesh, 1988
M.S., Instit. of Molecular Biology and Biotechnology, VUB, Belgium, 1993
Ph.D., Shimane Medical University, Japan, 2004
Postdoctoral, UT MD Anderson Cancer Center, Texas, 2006
Postdoctoral, University of Kansas Medical Center, Kansas, 2007


mrumi@kumc.edu
Soares Lab Website

Our laboratory is interested in the regulation of cell differentiation, especially as related to trophoblast stem cells, and signaling pathways controlling their developmental fate. We are also interested in species-specific reproductive adaptations to physiological stressors and signaling events involved in the establishment and maintenance of pregnancy; including investigations on the prolactin gene family, intrauterine inflammatory and immune cells, uterine vasculature, decidual cells, and the invasive trophoblast cell lineage.

Selected Publications

Asanoma K, Rumi MA, Kent LN, Chakraborty D, Renaud SJ, Wake N, Lee DS, Kubota K, Soares MJ. FGF4-dependent stem cells derived from rat blastocysts differentiate along the trophoblast lineage. Dev Biol. 2011 Mar 1; 351(1):110-9.

Konno T, Graham AR, Rempel LA, Ho-Chen JK, Alam SM, Bu P, Rumi MA, Soares MJ. Subfertility linked to combined luteal insufficiency and uterine progesterone resistance. Endocrinology. 2010 Sep; 151(9):4537-50.

Alam SM, Konno T, Rumi MA, Dong Y, Weiner CP, Soares MJ. Prolactin family of the guinea pig, Cavia porcellus. Endocrinology. 2010 Aug; 151(8):3918-28.

Lee DS, Rumi MA, Konno T, Soares MJ. In vivo genetic manipulation of the rat trophoblast cell lineage using lentiviral vector delivery. Genesis. 2009 Jul; 47(7):433-9.

Ray S, Dutta D, Rumi MA, Kent LN, Soares MJ, Paul S. Context-dependent function of regulatory elements and a switch in chromatin occupancy between GATA3 and GATA2 regulate Gata2 transcription during trophoblast differentiation. J Biol Chem. 2009 Feb 20; 284(8):4978-88.

Last modified: Feb 24, 2014

M.A. Karim Rumi, M.B.B.S., M.S., Ph.D.

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M.A. Karim Rumi, M.B.B.S., M.S., Ph.D.
Research Associate Professor
Dept. of Pathology and Laboratory Medicine

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