Jill Jacobson, M.D.

Professor, University of Missouri-Kansas City
Pediatric Endocrinology/Diabetes

MD, 1985, University of Miami School of Medicine, Miami, FL
Postdoctoral, 1985-1987, University of Pennsylvania

I am a pediatric endocrinologist with a longstanding interest in gender differences in expression of disease.  I am the Medical Director of our multidisciplinary clinic for Disorders of Sex Development (DSD), one  of the goals of which  is to increase our diagnosis rate. Currently 62% of our 91 DSD patients have received molecular/biochemical diagnoses, in contrast to the reported 20% diagnosis rate nationwide.    My work in DSD has naturally evolved to clinical expertise in gender dysphoria. We have begun a multidisciplinary clinic entitled Gender Pathways Services (GPS). In seeking biological bases for gender dysphoria and have uncovered high rates of hyperandrogenism, the CAH carrier state, as well as several genetic abnormalities. 

Jacobson JD, Nisula BC, Steinberg AD.  1993.  Modulation of expression of murine lupus by gonadotropin-releasing hormone analogues.  Endocrinology 134:2516‑2523.

Jacobson JD, Kinealy M, Muthukrishnan V, and Ansari MA, 1999. Gender specific exacerbation of murine lupus by gonadotropin-releasing hormone: Role of Gaq/11.  Endocrinology 140: 3429-3437.

Crofford, LJ, Jacobson, JD, Young, E.  1999.  New paradigms for modeling the involvement of neurohormonal axes in autoimmune and stress-related rheumatic syndromes in women.  Journal Women's Health.  8:203-215.

Morton TL, Ansari MA, Jacobson, JD.  2003. Gender Differences and Hormonal Modulation of Gαq/11 Expression in Lymphoid Organs. Neuroendocrinology 78: 147-53.

Jacobson JD, Ansari MA. 2004. Immunomodulatory Actions of Gonadal Steroids May be Mediated by Gonadotropin-Releasing Hormone Endocrinology 145: 337-342.

Flint, J, Jacobson JD. 2013. Adrenal Hypoplasia Congenita (AHC) presenting as congenital adrenal hyperplasia  Case Reports in Endocrinology  2013:393584.

Tsai SL, Seiler KJ, Jacobson JD. 2013. Morning Cortisol Levels Affected by Sex and Pubertal Status in Children. Journal of Clinical Research in Pediatric Endocrinology 5 (2) 85-89.

Jacobson JD, Nelson, AT, Sands SA.  2013.  Allergic manifestations and cutaneous histamine responses  in McCune Albright Syndrome. World Allergy Organization Journal May 1;6(1):9.

Jacobson JD, Ellerbeck KA, Kelly KA, Fleming KK, Jamison TR, Coffey CW, Smith CM,  Reese RM, and Sands SA. 2013. Evidence for alterations in stimulatory G proteins and oxytocin levels in children with autism. Psychoneuroendocrinology 40:159-69.

Jacobson JD, Strickland J, Smith LD,   Egan AM,  Willig LK,  Farrow EG,  Saunders CJ,  Kingsmore SF, Luetjen TL, and Gatti J. 2014.  Increasing the Diagnosis Rate in Patients with Disorders of Sex Development (DSD).  (Abstract) Oral presentation Endocrine Society Chicago, IL.

Last modified: Sep 08, 2014


Jill Jacobson, M.D.
Professor, University of Missouri-Kansas City